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HLA-B locus in Caucasian patients with carbamazepine hypersensitivity

21 January 2018

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HLA-A 31:01 and HLA-B 15:02 as genetic markers for carbamazepine hypersensitivity in children.

21 January 2018

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Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital

21 January 2018

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Towards the safer use of medicines

21 January 2018

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21 January 2018

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Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group

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The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group

21 January 2018

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Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury

21 January 2018

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HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients

21 January 2018

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Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan

21 January 2018

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Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

21 January 2018

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Medical genetics: a marker for Stevens-Johnson syndrome

21 January 2018

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Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality.

21 January 2018

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Genetic association studies in drug-induced liver injury

21 January 2018

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HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

21 January 2018

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Cutaneous adverse drug reactions seen in a tertiary hospital in Johor, Malaysia.

21 January 2018

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21 January 2018

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A screening study of drug-drug interactions in cerivastatin users: an adverse effect of clopidogrel

21 January 2018

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Statistical design of personalized medicine interventions: the Clarification of Optimal Anticoagulation through Genetics (COAG) trial

21 January 2018

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Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

21 January 2018

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Updated consensus statement on tumour necrosis factor blocking agents for the treatment of rheumatoid arthritis (May 2000)

21 January 2018

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Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions

21 January 2018

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Adverse drug reactions causing admission to a paediatric hospital

21 January 2018

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Danger signals: SOS to the immune system

21 January 2018

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P-glycoprotein--a mediator of multidrug resistance in tumour cells

21 January 2018

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Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity

21 January 2018

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Glutathione S-transferase mu genotype (GSTM1*0) in Alzheimer's patients with tacrine transaminitis

21 January 2018

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Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms.

21 January 2018

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HLA association of amoxicillin-clavulanate--induced hepatitis

21 January 2018

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Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir

21 January 2018

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Genetic variations in HLA-B region and hypersensitivity reactions to abacavir

21 January 2018

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Ticlopidine-induced hepatotoxicity is associated with specific human leukocyte antigen genomic subtypes in Japanese patients: a preliminary case-control study

21 January 2018

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Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations

21 January 2018

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Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

21 January 2018

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Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example

21 January 2018

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HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

21 January 2018

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Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

21 January 2018

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HLA class I markers in Japanese patients with carbamazepine-induced cutaneous adverse reactions

21 January 2018

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21 January 2018

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Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment

21 January 2018

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Estimation of the warfarin dose with clinical and pharmacogenetic data

21 January 2018

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HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis

21 January 2018

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Economic efficiency of genetic screening to inform the use of abacavir sulfate in the treatment of HIV.

21 January 2018

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High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients

21 January 2018

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The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria

21 January 2018

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Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in Koreans

21 January 2018

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Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase

21 January 2018

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Glutathione deficiency in alcoholics: risk factor for paracetamol hepatotoxicity

21 January 2018

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Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

21 January 2018

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Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts

21 January 2018

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HLA-Cw*04 allele associated with nevirapine-induced rash in HIV-infected Thai patients

21 January 2018

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HLA-dependent hypersensitivity to nevirapine in Sardinian HIV patients.

21 January 2018

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Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population.

21 January 2018

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A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs

21 January 2018

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Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

21 January 2018

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HLA-B*5701 screening for hypersensitivity to abacavir

21 January 2018

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Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese

21 January 2018

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Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts

21 January 2018

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Tolerance, danger, and the extended family

21 January 2018

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HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans

21 January 2018

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Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

21 January 2018

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Association of HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians

21 January 2018

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Drug interactions with cisapride: clinical implications

21 January 2018

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An electrophile responsive element (EpRE) regulates beta-naphthoflavone induction of the human gamma-glutamylcysteine synthetase regulatory subunit gene. Constitutive expression is mediated by an adjacent AP-1 site

21 January 2018

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Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element

21 January 2018

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Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment

21 January 2018

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Plasma cysteine deficiency and decreased reduction of nitrososulfamethoxazole with HIV infection

21 January 2018

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Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T cell clones

21 January 2018

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Molecular mechanisms of the hepatotoxicity caused by acetaminophen

21 January 2018

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Cost-effectiveness analysis of HLA-B*5701 typing in the prevention of hypersensitivity to abacavir in HIV+ patients in Spain.

21 January 2018

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Co-amoxiclav jaundice: clinical and histological features and HLA class II association.

21 January 2018

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Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population

21 January 2018

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Fixed drug eruption induced by trimethoprim-sulfamethoxazole: evidence for a link to HLA-A30 B13 Cw6 haplotype

21 January 2018

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What do we know about the genetics of aspirin intolerance?

21 January 2018

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Mechanisms of MHC class I--restricted antigen processing

21 January 2018

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Idiosyncratic drug reactions: a mechanistic evaluation of risk factors

21 January 2018

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The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity

21 January 2018

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Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

21 January 2018

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Metabolic activation in drug allergies.

21 January 2018

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The role of metabolic activation in drug-induced hepatotoxicity

21 January 2018

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Acute and chronic drug-induced hepatitis

21 January 2018

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Frequency of major complications of aspirin, warfarin, and intravenous heparin for secondary stroke prevention. A population-based study

21 January 2018

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Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response

21 January 2018

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Allergic reactions to drugs: involvement of T cells

21 January 2018

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Drug-grapefruit juice interactions

21 January 2018

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The pharmacogenomics of HIV therapy.

21 January 2018

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Genetic susceptibility to adverse drug reactions

21 January 2018

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Idiosyncratic reactions to antidepressants: A review of the possible mechanisms and predisposing factors

21 January 2018

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The Role of Active Metabolites in Drug Toxicity

21 January 2018

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Idiosyncratic drug reactions. Metabolic bioactivation as a pathogenic mechanism

21 January 2018

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21 January 2018

Adverse drug reactions

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Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity

21 January 2018

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Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

21 January 2018

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The immunologic and metabolic basis of drug hypersensitivities

21 January 2018

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Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study

21 January 2018

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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

21 January 2018

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Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

21 January 2018

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21 January 2018

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Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes

21 January 2018

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Pharmacogenetics and the practice of medicine

21 January 2018

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Risk of Stevens-Johnson syndrome and toxic epider mal necrolysis during first weeks of antiepileptic therapy: a case-control study

21 January 2018

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High sensitivity of human leukocyte antigen-b*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients

21 January 2018

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CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis

21 January 2018

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Hypertensive crisis and cheese

21 January 2018

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The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV.

21 January 2018

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Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones

21 January 2018

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The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

21 January 2018

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Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

21 January 2018

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A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

21 January 2018

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HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer

21 January 2018

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21 January 2018

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Human herpesvirus 6 infection as a risk factor for the development of severe drug-induced hypersensitivity syndrome

21 January 2018

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Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population

21 January 2018

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Association between HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in a Thai population

21 January 2018

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UDP-glucuronosyltransferases: a family of detoxifying enzymes

21 January 2018

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Complete sequence and gene map of a human major histocompatibility complex. The MHC sequencing consortium

21 January 2018

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New concepts in immunology relevant to idiosyncratic drug reactions: the "danger hypothesis" and innate immune system

21 January 2018

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Adverse reactions to co-trimoxazole in HIV infection

21 January 2018

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Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design

21 January 2018

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HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz

21 January 2018

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Common VKORC1 and GGCX polymorphisms associated with warfarin dose

21 January 2018

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A randomized trial of N-acetylcysteine for prevention of trimethoprim-sulfamethoxazole hypersensitivity reactions in Pneumocystis carinii pneumonia prophylaxis (CTN 057). Canadian HIV Trials Network 057 Study Group

21 January 2018

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Polymorphisms at position 245 of HIV reverse transcriptase do not accurately predict the presence of human leukocyte antigen B*5701.

21 January 2018

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Basic concepts in drug metabolism: Part I.

21 January 2018

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HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic review

21 January 2018

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HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes.

21 January 2018

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Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis

21 January 2018

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Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure

21 January 2018

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