(Q59356541)

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Kazuya Shirato

object named as

Kazuya Shirato

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author name string

Miyuki Kawase

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Yutaka Terada

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Kengo Kawachi

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Wataru Kamitani

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

7

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language of work or name

English

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publication date

1 October 2018

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published in

Journal of Virology

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volume

92

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issue

19

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cites work

1 reference

12 December 2020

A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

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12 December 2020

Furin at the cutting edge: from protein traffic to embryogenesis and disease

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12 December 2020

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

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12 December 2020

Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion

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12 December 2020

Inhibitors of proprotein convertases

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12 December 2020

A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness

1 reference

12 December 2020

Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide

1 reference

12 December 2020

Efficient multiplication of human metapneumovirus in Vero cells expressing the transmembrane serine protease TMPRSS2.

1 reference

12 December 2020

Entry from the cell surface of severe acute respiratory syndrome coronavirus with cleaved S protein as revealed by pseudotype virus bearing cleaved S protein.

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12 December 2020

Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites

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12 December 2020

Inhibition of furin/proprotein convertase-catalyzed surface and intracellular processing by small molecules

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12 December 2020

Two-step conformational changes in a coronavirus envelope glycoprotein mediated by receptor binding and proteolysis

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12 December 2020

On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications

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12 December 2020

Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases

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12 December 2020

Ready, set, fuse! The coronavirus spike protein and acquisition of fusion competence

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12 December 2020

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

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12 December 2020

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

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12 December 2020

Bilateral entry and release of Middle East respiratory syndrome coronavirus induces profound apoptosis of human bronchial epithelial cells

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12 December 2020

Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.

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12 December 2020

Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection

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12 December 2020

Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.

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12 December 2020

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

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12 December 2020

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

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12 December 2020

Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

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12 December 2020

Inability of rat DPP4 to allow MERS-CoV infection revealed by using a VSV pseudotype bearing truncated MERS-CoV spike protein

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12 December 2020

Fusion of Enveloped Viruses in Endosomes

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12 December 2020

Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay.

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12 December 2020

Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism

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12 December 2020

Proprotein convertase inhibition: Paralyzing the cell's master switches

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12 December 2020

Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.

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12 December 2020

MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA.

1 reference

12 December 2020