(Q59356620)

2

0 references

Anurupa Dev

3

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Saba Roghiyh Aliyari

4

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Shivam A Zaver

5

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Hoda Gerami

6

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Maxime Chapon

7

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Amir A Ghaffari

8

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Anant Dhingra

9

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Genhong Cheng

Creative Commons Attribution 4.0 International

10

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language of work or name

English

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publication date

17 July 2018

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published in

Nature Communications

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volume

9

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issue

1

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page(s)

2770

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copyright license

start time

17 July 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6050272/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s41467-018-05168-7

0 references

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Immune sensing of DNA

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Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

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Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

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IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

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7 January 2021

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

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7 January 2021

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

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7 January 2021

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

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7 January 2021

Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity.

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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

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The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

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Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

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ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

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7 January 2021

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

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PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation

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7 January 2021

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

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The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling

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Targeting signaling factors for degradation, an emerging mechanism for TRAF functions

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Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

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STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease

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7 January 2021

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

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7 January 2021

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

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7 January 2021

TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING

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TRIM29 promotes DNA virus infections by inhibiting innate immune response

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7 January 2021

iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.

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7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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7 January 2021

Non-canonical NF-κB signaling activation and regulation: principles and perspectives

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7 January 2021

Identification and characterization of an IkappaB kinase

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7 January 2021

The noncanonical NF-κB pathway

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7 January 2021

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

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7 January 2021

Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization

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7 January 2021

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

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The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

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7 January 2021

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

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7 January 2021

Unclogging sickle cell anaemia

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7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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7 January 2021

Crystal structure and mechanism of activation of TANK-binding kinase 1

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7 January 2021

Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

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7 January 2021

Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation

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7 January 2021

Triggering the interferon antiviral response through an IKK-related pathway

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7 January 2021

Molecular determinants of NF-kappaB-inducing kinase action

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7 January 2021

The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.

1 reference

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7 January 2021

iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Filament assemblies in foreign nucleic acid sensors

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways

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7 January 2021

Translating nucleic acid-sensing pathways into therapies

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https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Cytokine determinants of viral tropism.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Rescue of TRAF3-null mice by p100 NF-kappa B deficiency

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases

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https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Fiji: an open-source platform for biological-image analysis

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https://api.crossref.org/works/10.1038%2FS41467-018-05168-7

7 January 2021

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30018345

12 December 2020

inferred from PubMed ID database lookup

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30018345

12 December 2020