(Q64130726)

English

Benzo[a]pyrene-induced cell cycle progression is through ERKs/cyclin D1 pathway and requires the activation of JNKs and p38 mapk in human diploid lung fibroblasts

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scholarly article

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Benzo[a]pyrene-induced cell cycle progression is through ERKs/cyclin D1 pathway and requires the activation of JNKs and p38 mapk in human diploid lung fibroblasts (English)

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author name string

Hong Ju Du

1

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Ning Tang

2

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Bing Ci Liu

3

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Bao Rong You

4

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Fu Hai Shen

5

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Meng Ye

6

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Ai Gao

7

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Chuan shu Huang

8

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language of work or name

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publication date

July 2006

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Molecular and Cellular Biochemistry

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287

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1-2

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79-89

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c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress-induced apoptosis is mediated by ERK1/2 phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of dibenzo[a,1]pyrene and benzo[a]pyrene on human diploid lung fibroblasts: the induction of DNA adducts, expression of p53 and p21(WAF1) proteins and cell cycle distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated Protein Kinases and Activator Protein 1 Are Required for Proliferation and Cardiomyocyte Differentiation of P19 Embryonal Carcinoma Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperexpression of mitogen-activated protein kinase in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carcinogen biomarkers related to smoking and upper aerodigestive tract cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle control in normal and neoplastic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction through MAP kinase cascades

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p38 signal transduction pathway: activation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoplastic transformation of human lung fibroblast MRC-5 SV2 cells induced by benzo[a]pyrene and confluence culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malignant transformation of human fibroblast cell strain MSU-1.1 by (+-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo [a]pyrene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian MAP kinase signalling cascades

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G1 phase progression: cycling on cue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of cyclins D1 and E is frequent in bronchial preneoplasia and precedes squamous cell carcinoma development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian G1 cyclins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G1-specific cyclins: in search of an S-phase-promoting factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian G1- and S-phase checkpoints in response to DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 protein expression and function in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and amplification of cyclin genes in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parallel signal processing among mammalian MAPKs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic and benzo[a]pyrene differentially alter the capacity for differentiation and growth properties of primary human epidermal keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM) on human diploid lung fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Recombination and identification of sense and antisense cyclinD1 eukaryotic expression vectors].

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanded analysis of benzo[a]pyrene-DNA adducts formed in vitro and in mouse skin: their significance in tumor initiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple ras effector pathways contribute to G(1) cell cycle progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diverse chemical carcinogens fail to induce G(1) arrest in MCF-7 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G1 events and regulation of cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta stimulates articular chondrocyte cell growth through p44/42 MAP kinase (ERK) activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of cyclin D1 and CDK4 gene in carcinoma of uterine cervix

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced proliferation of human MRC-5 cells by nitrogen oxides via direct and indirect activation of MEKK1, JNK, and p38 signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dominant role for the c-Jun NH2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Over-expression of cyclin D1 regulates Cdk4 protein synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osmotic stress regulates the stability of cyclin D1 in a p38SAPK2-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Principles of CDK regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression of cyclin D1 and CDK4 genes in ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of defective mitogenic signaling by D-type cyclins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16699726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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