(Q79185010)

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Hepatocyte growth factor signaling regulates transactivation of genes belonging to the plasminogen activation system via hypoxia inducible factor-1

scientific article published on 01 November 2003

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20 December 2019

Hepatocyte growth factor signaling regulates transactivation of genes belonging to the plasminogen activation system via hypoxia inducible factor-1 (English)

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20 December 2019

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Lorenza Tacchini

1

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20 December 2019

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Emanuela Matteucci

2

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20 December 2019

Cristina De Ponti

3

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20 December 2019

Maria Alfonsina Desiderio

4

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20 December 2019

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1 November 2003

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20 December 2019

Experimental Cell Research

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20 December 2019

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20 December 2019

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20 December 2019

391-401

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20 December 2019

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HGF/scatter factor selectively promotes cell invasion by increasing integrin avidity

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The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis

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Integrin signaling revisited

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Urokinase receptor: a molecular organizer in cellular communication.

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The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies

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7 January 2021

Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells

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7 January 2021

Signal transduction to hypoxia-inducible factor 1

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7 January 2021

The subtle side to hypoxia inducible factor (HIFalpha) regulation

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HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

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Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms

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7 January 2021

Increased Sp1 phosphorylation as a mechanism of hepatocyte growth factor (HGF/SF)-induced vascular endothelial growth factor (VEGF/VPF) transcription

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7 January 2021

Activation mechanisms of the urokinase-type plasminogen activator promoter by hepatocyte growth factor/scatter factor

1 reference

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7 January 2021

Binding of Sp1 to the proximal promoter links constitutive expression of the human uPA gene and invasive potential of PC3 cells.

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7 January 2021

Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia

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7 January 2021

Purification and characterization of hypoxia-inducible factor 1

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7 January 2021

The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair

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7 January 2021

Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways

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7 January 2021

Hepatocyte growth factor induces apoptosis through the extrinsic pathway in hepatoma cells: favouring role of hypoxia-inducible factor-1 deficiency

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7 January 2021

Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

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A cytoplasmic inhibitor of the JNK signal transduction pathway

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c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription.

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7 January 2021

Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1.

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7 January 2021

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

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7 January 2021

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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7 January 2021

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

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7 January 2021

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

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7 January 2021

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

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7 January 2021

Hepatocyte growth factor induces pro-apoptotic genes in HepG2 hepatoma but not in B16-F1 melanoma cells

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7 January 2021

Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation

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7 January 2021

HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation

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7 January 2021

Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription

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Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.

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Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

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Identifiers

10.1016/S0014-4827(03)00348-3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567996%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567996%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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