(Q79767255)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17297463%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2 (English)

1 reference

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25 December 2019

1 reference

D L F Chang

1

1 reference

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25 December 2019

W Qiu

2

1 reference

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25 December 2019

H Ying

3

1 reference

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25 December 2019

Y Zhang

4

1 reference

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25 December 2019

C-Y Chen

5

1 reference

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25 December 2019

Z-X J Xiao

6

1 reference

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25 December 2019

publication date

5 February 2007

1 reference

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25 December 2019

1 reference

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25 December 2019

volume

26

1 reference

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25 December 2019

issue

32

1 reference

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25 December 2019

page(s)

4627-4634

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210254

25 December 2019

exact match

0 references

cites work

Defining the molecular basis of Arf and Hdm2 interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Acetylation control of the retinoblastoma tumour-suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Alterations and hypermethylation of the p14(ARF) gene in gastric cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Acetylation regulates the differentiation-specific functions of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

P19ARF inhibits the functions of the HPV16 E7 oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

A melanoma-associated germline mutation in exon 1beta inactivates p14ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The INK4a/ARF locus in murine tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The INK4a/ARF network in tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

c-Abl neutralizes the inhibitory effect of Mdm2 on p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Yin Yang 1 is a negative regulator of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

ARF mutation accelerates pituitary tumor development in Rb+/- mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Selective deletion of p14(ARF) exon 1beta of the INK4a locus in oral squamous cell carcinomas of Indians

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

p53-independent functions of the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Targeting retinoblastoma protein for degradation by proteasomes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210254

7 January 2021