(Q84315401)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30849247%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

title

Broad-spectrum coronavirus antiviral drug discovery (English)

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28 April 2020

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1

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28 April 2020

2

Sina Bavari

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30849247%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

publication date

8 March 2019

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Expert Opinion on Drug Discovery

28 April 2020

published in

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28 April 2020

volume

14

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28 April 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30849247%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

page(s)

397-412

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Strategy for systematic assembly of large RNA and DNA genomes: transmissible gastroenteritis virus model

28 April 2020

cites work

1 reference

12 December 2020

Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59.

1 reference

12 December 2020

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

1 reference

12 December 2020

A novel coronavirus associated with severe acute respiratory syndrome

1 reference

12 December 2020

Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome.

1 reference

12 December 2020

Short term outcome and risk factors for adverse clinical outcomes in adults with severe acute respiratory syndrome (SARS)

1 reference

12 December 2020

Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.

1 reference

12 December 2020

Treatment of SARS with human interferons

1 reference

12 December 2020

Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China

1 reference

12 December 2020

Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus

1 reference

12 December 2020

Virology: SARS virus infection of cats and ferrets

1 reference

12 December 2020

Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques.

1 reference

12 December 2020

Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings.

1 reference

12 December 2020

Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha

1 reference

12 December 2020

Identification of a new human coronavirus

1 reference

12 December 2020

Small molecules targeting severe acute respiratory syndrome human coronavirus

1 reference

12 December 2020

Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice

1 reference

12 December 2020

Macaque model for severe acute respiratory syndrome

1 reference

12 December 2020

Symptoms of infection caused by SARS coronavirus in laboratory mice and guinea pigs.

1 reference

12 December 2020

Replication of SARS coronavirus administered into the respiratory tract of African Green, rhesus and cynomolgus monkeys.

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters

1 reference

12 December 2020

Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human

1 reference

12 December 2020

Pneumonitis and multi-organ system disease in common marmosets (Callithrix jacchus) infected with the severe acute respiratory syndrome-associated coronavirus

1 reference

12 December 2020

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs

1 reference

12 December 2020

SARS-associated coronavirus replication in cell lines

1 reference

12 December 2020

Cynomolgus macaque as an animal model for severe acute respiratory syndrome

1 reference

12 December 2020

Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin.

1 reference

12 December 2020

Molecular diversity of coronaviruses in bats.

1 reference

12 December 2020

SARS: systematic review of treatment effects

1 reference

12 December 2020

SARS coronavirus accessory ORFs encode luxury functions

1 reference

12 December 2020

A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo

1 reference

12 December 2020

Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features

1 reference

12 December 2020

Development and validation of a high-throughput screen for inhibitors of SARS CoV and its application in screening of a 100,000-compound library

1 reference

12 December 2020

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

1 reference

12 December 2020

Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice

1 reference

12 December 2020

Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies

1 reference

12 December 2020

Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium

1 reference

12 December 2020

Pathways of cross-species transmission of synthetically reconstructed zoonotic severe acute respiratory syndrome coronavirus

1 reference

12 December 2020

High-throughput assay using a GFP-expressing replicon for SARS-CoV drug discovery

1 reference

12 December 2020

Human airway epithelial cell culture to identify new respiratory viruses: coronavirus NL63 as a model

1 reference

12 December 2020

Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice

1 reference

12 December 2020

Titration of human coronaviruses, HcoV-229E and HCoV-OC43, by an indirect immunoperoxidase assay.

1 reference

12 December 2020

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

1 reference

12 December 2020

Exacerbated innate host response to SARS-CoV in aged non-human primates

1 reference

12 December 2020

Severe Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological Evaluation

1 reference

12 December 2020

Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures

1 reference

12 December 2020

Estimates of deaths associated with seasonal influenza --- United States, 1976-2007.

1 reference

12 December 2020

Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus

1 reference

12 December 2020

Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species

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12 December 2020

A diverse range of gene products are effectors of the type I interferon antiviral response

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12 December 2020

Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques

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12 December 2020

A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge

1 reference

12 December 2020

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

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12 December 2020

Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections

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12 December 2020

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

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12 December 2020

Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism

1 reference

12 December 2020

Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation

1 reference

12 December 2020

Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin

1 reference

12 December 2020

The Middle East respiratory syndrome coronavirus (MERS-CoV) does not replicate in Syrian hamsters

1 reference

12 December 2020

Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury

1 reference

12 December 2020

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques

1 reference

12 December 2020

Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques

1 reference

12 December 2020

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

1 reference

12 December 2020

Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS.

1 reference

12 December 2020

Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus in bats, Saudi Arabia

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12 December 2020

Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses

1 reference

12 December 2020

Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus

1 reference

12 December 2020

Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays

1 reference

12 December 2020

Atlas of coronavirus replicase structure.

1 reference

12 December 2020

Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay

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12 December 2020

Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia

1 reference

12 December 2020

Rapid generation of a mouse model for Middle East respiratory syndrome

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12 December 2020

A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant

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12 December 2020

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

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12 December 2020

Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection

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12 December 2020

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

1 reference

12 December 2020

Infection with MERS-CoV causes lethal pneumonia in the common marmoset

1 reference

12 December 2020

Tropism and replication of Middle East respiratory syndrome coronavirus from dromedary camels in the human respiratory tract: an in-vitro and ex-vivo study.

1 reference

12 December 2020

Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26

1 reference

12 December 2020

Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness

1 reference

12 December 2020

Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

1 reference

12 December 2020

Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease

1 reference

12 December 2020

Protease inhibitors targeting coronavirus and filovirus entry

1 reference

12 December 2020

Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus

1 reference

12 December 2020

Asymptomatic Middle East respiratory syndrome coronavirus infection in rabbits

1 reference

12 December 2020

Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study

1 reference

12 December 2020

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

1 reference

12 December 2020

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

1 reference

12 December 2020

Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease

1 reference

12 December 2020

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

1 reference

12 December 2020

Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea, 2015.

1 reference

12 December 2020

Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4.

1 reference

12 December 2020

Combination therapy with lopinavir/ritonavir, ribavirin and interferon-α for Middle East respiratory syndrome

1 reference

12 December 2020

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

1 reference

12 December 2020

An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels

1 reference

12 December 2020

Environmental Contamination and Viral Shedding in MERS Patients During MERS-CoV Outbreak in South Korea

1 reference

12 December 2020

MERS coronavirus: diagnostics, epidemiology and transmission

1 reference

12 December 2020

3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012

1 reference

12 December 2020

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

1 reference

12 December 2020

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

1 reference

12 December 2020

Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).

1 reference

12 December 2020

SARS-like WIV1-CoV poised for human emergence

1 reference

12 December 2020

Taking forward a ‘ONE HEALTH’ approach for turning the tide against The Middle East Respiratory Syndrome Coronavirus and other zoonotic pathogens with epidemic potential

1 reference

12 December 2020

Safe and Sensitive Antiviral Screening Platform Based on Recombinant Human Coronavirus OC43 Expressing the Luciferase Reporter Gene

1 reference

12 December 2020

Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model

1 reference

12 December 2020

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

1 reference

12 December 2020

First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease

1 reference

12 December 2020

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses

1 reference

12 December 2020

Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice

1 reference

12 December 2020

Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus

1 reference

12 December 2020

Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses

1 reference

12 December 2020

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

1 reference

12 December 2020

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

1 reference

12 December 2020

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.

1 reference

12 December 2020

Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial

1 reference

12 December 2020

Advanced Microengineered Lung Models for Translational Drug Discovery

1 reference

12 December 2020

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

1 reference

12 December 2020

Hosts and Sources of Endemic Human Coronaviruses.

1 reference

12 December 2020

Human Coronaviruses and other Respiratory Infections in Young Adults on a University Campus: Prevalence, Symptoms, and Shedding.

1 reference

12 December 2020

Clinical outcomes of current medical approaches for Middle East respiratory syndrome: A systematic review and meta-analysis.

1 reference

12 December 2020

Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice

1 reference

12 December 2020

10.1080/17460441.2019.1581171

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30849247%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30849247%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

1 reference