(Q88964560)

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29 March 2020

title

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR (English)

1 reference

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29 March 2020

author name string

Zandra E Walton

1

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29 March 2020

Chirag H Patel

2

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29 March 2020

Rebekah C Brooks

3

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29 March 2020

Yongjun Yu

4

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29 March 2020

Arig Ibrahim-Hashim

5

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29 March 2020

Malini Riddle

6

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29 March 2020

Alessandra Porcu

7

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29 March 2020

Tianying Jiang

8

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29 March 2020

Brett L Ecker

9

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29 March 2020

Feven Tameire

10

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29 March 2020

Constantinos Koumenis

11

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29 March 2020

Ashani T Weeraratna

12

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29 March 2020

David K Welsh

13

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29 March 2020

Robert Gillies

14

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29 March 2020

James C Alwine

15

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29 March 2020

Lin Zhang

16

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29 March 2020

Jonathan D Powell

17

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29 March 2020

Chi V Dang

18

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29 March 2020

publication date

31 May 2018

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29 March 2020

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29 March 2020

volume

174

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29 March 2020

issue

1

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29 March 2020

page(s)

72-87.e32

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Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH

29 March 2020

cites work

1 reference

12 December 2020

Intracellular pH controls growth factor-induced ribosomal protein S6 phosphorylation and protein synthesis in the G0----G1 transition of fibroblasts

1 reference

12 December 2020

Cytoplasmic pH, a key determinant of growth factor-induced DNA synthesis in quiescent fibroblasts

1 reference

12 December 2020

Enhancement of chemotherapy by manipulation of tumour pH.

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12 December 2020

Circadian clock regulation of pH in the rabbit retina.

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12 December 2020

MRI of the tumor microenvironment.

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12 December 2020

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

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12 December 2020

Real-time luminescence reporting of circadian gene expression in mammals.

1 reference

12 December 2020

Identification of novel single amino acid changes that result in hyperactivation of the unique GTPase, Rheb, in fission yeast

1 reference

12 December 2020

Hypoxia and circadian patterns

1 reference

12 December 2020

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

1 reference

12 December 2020

Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin

1 reference

12 December 2020

A genome-wide RNAi screen for modifiers of the circadian clock in human cells

1 reference

12 December 2020

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling

1 reference

12 December 2020

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

1 reference

12 December 2020

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

1 reference

12 December 2020

Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock

1 reference

12 December 2020

Analyzing circadian expression data by harmonic regression based on autoregressive spectral estimation

1 reference

12 December 2020

AKT and TOR signaling set the pace of the circadian pacemaker

1 reference

12 December 2020

Lysosomal positioning coordinates cellular nutrient responses.

1 reference

12 December 2020

Human cytomegalovirus infection maintains mTOR activity and its perinuclear localization during amino acid deprivation

1 reference

12 December 2020

Regulation of mTORC1 signaling by pH

1 reference

12 December 2020

Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling

1 reference

12 December 2020

Dynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cells

1 reference

12 December 2020

Histone acetylation regulates intracellular pH.

1 reference

12 December 2020

Acidity generated by the tumor microenvironment drives local invasion

1 reference

12 December 2020

The circadian clock coordinates ribosome biogenesis

1 reference

12 December 2020

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.

1 reference

12 December 2020

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

1 reference

12 December 2020

Genome-scale CRISPR-Cas9 knockout screening in human cells

1 reference

12 December 2020

Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome

1 reference

12 December 2020

Circadian timing of metabolism in animal models and humans

1 reference

12 December 2020

Ligand-Occupied Integrin Internalization Links Nutrient Signaling to Invasive Migration

1 reference

12 December 2020

Molecular Mechanism for the Control of Eukaryotic Elongation Factor 2 Kinase by pH: Role in Cancer Cell Survival

1 reference

12 December 2020

mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation

1 reference

12 December 2020

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation

1 reference

12 December 2020

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

1 reference

12 December 2020

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

1 reference

12 December 2020

A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation.

1 reference

12 December 2020

The position of lysosomes within the cell determines their luminal pH

1 reference

12 December 2020

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

1 reference

12 December 2020

MetaCycle: an integrated R package to evaluate periodicity in large scale data

1 reference

12 December 2020

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

1 reference

12 December 2020

Dynamics of mTORC1 activation in response to amino acids.

1 reference

12 December 2020

Rhythmic Oxygen Levels Reset Circadian Clocks through HIF1α.

1 reference

12 December 2020

Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle.

1 reference

12 December 2020

Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals.

1 reference

12 December 2020

Transcriptional architecture of the mammalian circadian clock

1 reference

12 December 2020

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

1 reference

12 December 2020

Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution.

1 reference

12 December 2020

mTOR Signaling in Growth, Metabolism, and Disease.

1 reference

12 December 2020

The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway

1 reference

12 December 2020

10.1016/J.CELL.2018.05.009

Identifiers

DOI

1 reference

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29 March 2020

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29 March 2020

PubMed publication ID

29861175

1 reference