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Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases
scientific article published on 26 September 2018
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Europe PubMed Central
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6375686
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24 April 2020
title
Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases
(English)
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Europe PubMed Central
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6375686
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30258241%20AND%20SRC:MED&resulttype=core&format=json
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24 April 2020
author
Mathias Jucker
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1
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Europe PubMed Central
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6375686
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24 April 2020
author name string
Lary C Walker
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2
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Europe PubMed Central
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6375686
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24 April 2020
publication date
26 September 2018
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Europe PubMed Central
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6375686
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24 April 2020
published in
Nature Neuroscience
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Europe PubMed Central
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6375686
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24 April 2020
volume
21
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6375686
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30258241%20AND%20SRC:MED&resulttype=core&format=json
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24 April 2020
issue
10
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Europe PubMed Central
PMCID
6375686
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30258241%20AND%20SRC:MED&resulttype=core&format=json
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24 April 2020
page(s)
1341-1349
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Europe PubMed Central
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6375686
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24 April 2020
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23 February 2021
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
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23 February 2021
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease
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PubMed Central
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23 February 2021
Neurodegenerative diseases: expanding the prion concept
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23 February 2021
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23 February 2021
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23 February 2021
Rapidly progressive Alzheimer's disease features distinct structures of amyloid-β.
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23 February 2021
Progression of Seed-Induced Aβ Deposition within the Limbic Connectome
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23 February 2021
A new prion disease: relationship with central and peripheral amyloidoses
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23 February 2021
Spreading of pathology in neurodegenerative diseases: a focus on human studies
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23 February 2021
Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brains
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23 February 2021
Conformation determines the seeding potencies of native and recombinant Tau aggregates
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23 February 2021
Formaldehyde-fixed brain tissue from spontaneously ill α-synuclein transgenic mice induces fatal α-synucleinopathy in transgenic hosts.
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23 February 2021
Experimental transmissibility of mutant SOD1 motor neuron disease
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23 February 2021
Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid
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PubMed Central
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23 February 2021
Aβ seeds resist inactivation by formaldehyde
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PubMed Central
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23 February 2021
Pathological alpha-synuclein propagates through neural networks
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PubMed Central
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23 February 2021
Multiple factors contribute to the peripheral induction of cerebral β-amyloidosis.
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23 February 2021
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
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PubMed Central
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23 February 2021
Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients
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23 February 2021
Synthesis of high titer infectious prions with cofactor molecules
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Distinct tau prion strains propagate in cells and mice and define different tauopathies
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Mutant huntingtin is present in neuronal grafts in Huntington disease patients
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23 February 2021
Neuronal activity regulates extracellular tau in vivo
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Biology and genetics of prions causing neurodegeneration
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Distinct α-synuclein strains differentially promote tau inclusions in neurons
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Brain homogenates from human tauopathies induce tau inclusions in mouse brain
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Tau pathology and neurodegeneration
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23 February 2021
Prion-like spreading of pathological α-synuclein in brain
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Evaluation of potential infectivity of Alzheimer and Parkinson disease proteins in recipients of cadaver-derived human growth hormone
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
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23 February 2021
The spectrum of disease in chronic traumatic encephalopathy
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23 February 2021
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
100 years of Lewy pathology.
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23 February 2021
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C).
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23 February 2021
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions
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23 February 2021
Iatrogenic Creutzfeldt-Jakob disease, final assessment
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23 February 2021
Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease
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23 February 2021
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
The amyloid state of proteins in human diseases
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23 February 2021
Propagation of tau pathology in a model of early Alzheimer's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Trans-synaptic spread of tau pathology in vivo
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23 February 2021
An overview of human prion diseases
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23 February 2021
The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain
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23 February 2021
An overview of animal prion diseases
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23 February 2021
Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition
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23 February 2021
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23 February 2021
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23 February 2021
Neuronal activity regulates the regional vulnerability to amyloid-β deposition
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23 February 2021
Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis
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23 February 2021
Darwinian evolution of prions in cell culture
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23 February 2021
Prions: protein aggregation and infectious diseases
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23 February 2021
Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation
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23 February 2021
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6375686
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23 February 2021
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
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23 February 2021
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23 February 2021
Induction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic mice
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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6375686
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30258241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
PMCID
6375686
1 reference
stated in
Europe PubMed Central
PMCID
6375686
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30258241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
PubMed ID
30258241
1 reference
stated in
Europe PubMed Central
PMCID
6375686
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30258241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
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