(Q92125880)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

review article

1 reference

title

Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

0 references

0 references

evasion of host immune response

1 reference

based on heuristic

inferred from title

author

Jose Pedro Friedmann Angeli

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

Dmitri V Krysko

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

Marcus Conrad

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

publication date

1 July 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

page(s)

405-414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

Regulated necrosis: disease relevance and therapeutic opportunities

27 April 2020

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Ferroptosis: an iron-dependent form of nonapoptotic cell death

9 October 2020

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

9 October 2020

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Regulation of ferroptotic cancer cell death by GPX4

9 October 2020

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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.

9 October 2020

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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

9 October 2020

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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

9 October 2020

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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

9 October 2020

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Identification of ACSL4 as a biomarker and contributor of ferroptosis

9 October 2020

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Ferroptosis: The Greasy Side of Cell Death

9 October 2020

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Quantitative Profiling of Protein Carbonylations in Ferroptosis by an Aniline-Derived Probe.

9 October 2020

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The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production

9 October 2020

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Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

9 October 2020

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Glutaminolysis and Transferrin Regulate Ferroptosis

9 October 2020

1 reference

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Ferroptosis is an autophagic cell death process

9 October 2020

1 reference

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Autophagy promotes ferroptosis by degradation of ferritin

9 October 2020

1 reference

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An essential role for functional lysosomes in ferroptosis of cancer cells.

9 October 2020

1 reference

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Regulation of lipid peroxidation and ferroptosis in diverse species.

9 October 2020

1 reference

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The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

9 October 2020

1 reference

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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

9 October 2020

1 reference

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Ferroptosis as a p53-mediated activity during tumour suppression

9 October 2020

1 reference

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Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress.

9 October 2020

1 reference

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PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers

9 October 2020

1 reference

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9 October 2020

Glutathione peroxidases

1 reference

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Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Translating p53 into the clinic.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Role of NOX2-Derived Reactive Oxygen Species in NK Cell-Mediated Control of Murine Melanoma Metastasis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

9 October 2020

1 reference

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The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity.

9 October 2020

1 reference

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9 October 2020

1 reference

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BAP1 links metabolic regulation of ferroptosis to tumour suppression

9 October 2020

1 reference

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NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

EGLN1/c-Myc Induced Lymphoid-Specific Helicase Inhibits Ferroptosis through Lipid Metabolic Gene Expression Changes

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

ZEB1-mediated melanoma cell plasticity enhances resistance to MAPK inhibitors

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Immunosuppression associated with chronic inflammation in the tumor microenvironment

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Mutant p53 reprograms TNF signaling in cancer cells through interaction with the tumor suppressor DAB2IP.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The basics of epithelial-mesenchymal transition

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Eicosanoid and Specialized Proresolving Mediator Regulation of Lymphoid Cells

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Inhibition of arachidonate metabolism in human epidermoid carcinoma a431 cells overexpressing phospholipid hydroperoxide glutathione peroxidase

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Regulation of cyclooxygenase and 12-lipoxygenase catalysis by phospholipid hydroperoxide glutathione peroxidase in A431 cells.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Inhibitory effect of phospholipid hydroperoxide glutathione peroxidase on the activity of lipoxygenases and cyclooxygenases

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Depletion of phospholipid hydroperoxide glutathione peroxidase up-regulates arachidonate metabolism by 12S-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The eicosanoids, redox regulated lipid mediators in immunometabolic disorders

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Membrane redox state and apoptosis: death by peroxide

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The isoprostanes--25 years later

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Circulating levels of inflammatory cytokines and risk of colorectal adenomas

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Oxidatively truncated phospholipids are required agents of tumor necrosis factor α (TNFα)-induced apoptosis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The Dynamics of Apoptotic Cell Clearance

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Three cell deaths and a funeral: macrophage clearance of cells undergoing distinct modes of cell death

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

9 October 2020

Eicosanoids and cancer

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Ferroptosis: Oxidized PEs trigger death.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Oxidatively modified phosphatidylserines on the surface of apoptotic cells are essential phagocytic 'eat-me' signals: cleavage and inhibition of phagocytosis by Lp-PLA2

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Oxidized lipids block antigen cross-presentation by dendritic cells in cancer

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The release and activity of HMGB1 in ferroptosis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Synchronized renal tubular cell death involves ferroptosis.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

The Role of Prostaglandin E(2) in Tumor-Associated Immunosuppression

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Regulation of immune responses by prostaglandin E2

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Oxidized Phospholipids Negatively Regulate Dendritic Cell Maturation Induced by TLRs and CD40

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Salinomycin kills cancer stem cells by sequestering iron in lysosomes.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Ferroptosis: A Novel Anti-Tumor Action for Cisplatin.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Ferroptosis as a target for protection against cardiomyopathy

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Multifunctional nanoplatform for photoacoustic imaging-guided combined therapy enhanced by CO induced ferroptosis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Regulation of protein tyrosine phosphatases by reversible oxidation

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Phospholipid hydroperoxide glutathione peroxidase induces a delay in G1 of the cell cycle.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

TWEAK and RIPK1 mediate a second wave of cell death during AKI.

9 October 2020

1 reference

https://api.crossref.org/works/10.1038/S41568-019-0149-1

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

9 October 2020

1 reference

https://api.crossref.org/works/10.1038%2FS41568-019-0149-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41568-019-0149-1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31101865%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

1 reference