(Q93012784)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

title

Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

0 references

0 references

1 reference

2

1 reference

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3 May 2020

Emanuel Gonçalves

4

1 reference

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3 May 2020

Giorgia Migliardi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Francesco Sassi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Marika Pinnelli

10

1 reference

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3 May 2020

Piers Wilkinson

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Livio Trusolino

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Julio Saez-Rodriguez

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

20

Andrea Bertotti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

author name string

Fiona M Behan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Gabriele Picco

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Charlotte M Beaver

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Rita Santos

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Yanhua Rao

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Rizwan Ansari

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Sarah Harper

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

David Adam Jackson

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Rebecca McRae

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Rachel Pooley

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Dieudonne van der Meer

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

David Dow

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Carolyn Buser-Doepner

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Euan A Stronach

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Kosuke Yusa

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Mathew J Garnett

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

language of work or name

English

0 references

publication date

10 April 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

volume

568

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

page(s)

511-516

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

issue

7753

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 May 2020

1 reference

Genomics-driven oncology: framework for an emerging paradigm

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Clinical development success rates for investigational drugs

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Cell Model Passports-a hub for clinical, genetic and functional datasets of preclinical cancer models

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

A landscape of pharmacogenomic interactions in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Genetic screens in human cells using the CRISPR-Cas9 system

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

PI3K inhibitors as new cancer therapeutics: implications for clinical trial design

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Approaches to target tractability assessment - a practical perspective

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

RecQ helicases: multifunctional genome caretakers

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

A molecular portrait of microsatellite instability across multiple cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Genetic Instability Caused by Loss of MutS Homologue 3 in Human Colorectal Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

WRN helicase is a synthetic lethal target in microsatellite unstable cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Defining a Cancer Dependency Map.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

AuPairWise: A Method to Estimate RNA-Seq Replicability through Co-expression

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

BAGEL: a computational framework for identifying essential genes from pooled library screens.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

The human ribosomal protein genes: sequencing and comparative analysis of 73 genes

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Differential expression analysis for sequence count data

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Pathway Commons, a web resource for biological pathway data

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Pathway-based dissection of the genomic heterogeneity of cancer hallmarks' acquisition with SLAPenrich.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

The Genotype-Tissue Expression (GTEx) project

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

GDSCTools for Mining Pharmacogenomic Interactions in Cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Statistical significance for genomewide studies

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

Transcription factor activities enhance markers of drug sensitivity in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

limma powers differential expression analyses for RNA-sequencing and microarray studies

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

LAS: a software platform to support oncological data management

1 reference

https://api.crossref.org/works/10.1038%2FS41586-019-1103-9

7 January 2021

10.1038/S41586-019-1103-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30971826%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference