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Rho GTPases in cancer: friend or foe?
scientific article published on 19 August 2019
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Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
review article
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Europe PubMed Central
title
Rho GTPases in cancer: friend or foe?
(English)
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Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
author name string
Julius H Svensmark
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1
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Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
Cord Brakebusch
series ordinal
2
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Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
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1 May 2020
publication date
19 August 2019
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Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
published in
Oncogene
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Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
volume
38
1 reference
stated in
Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
issue
50
1 reference
stated in
Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
page(s)
7447-7456
1 reference
stated in
Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
cites work
Rho GTPases: biochemistry and biology
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GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
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7 January 2021
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Rho GTPase function in development: how in vivo models change our view
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7 January 2021
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Regulating Rho GTPases and their regulators
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Crossref
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7 January 2021
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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
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Crossref
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7 January 2021
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GEFs and GAPs: critical elements in the control of small G proteins
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7 January 2021
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The 'invisible hand': regulation of RHO GTPases by RHOGDIs
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Crossref
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7 January 2021
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Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships
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Crossref
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7 January 2021
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Rho GTPases and cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPase signaling complexes in cell migration and invasion
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
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A novel Cdc42Hs mutant induces cellular transformation
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
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Deregulation of Rho GTPases in cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Rac GTPase in Cancer: From Old Concepts to New Paradigms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases as therapeutic targets in cancer (Review).
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
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Rho GTPases: Anti- or pro-neoplastic targets?
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
RHO GTPases in cancer: known facts, open questions, and therapeutic challenges
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
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Crossref
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7 January 2021
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Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
RhoA, RhoB and RhoC have different roles in cancer cell migration
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB.
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The RhoB small GTPase in physiology and disease
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comprehensive molecular characterization of gastric adenocarcinoma
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery and saturation analysis of cancer genes across 21 tumour types
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
ARHGAP18 Downregulation by miR-200b Suppresses Metastasis of Triple-Negative Breast Cancer by Enhancing Activation of RhoA.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic RHOA mutation in angioimmunoblastic T cell lymphoma.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variegated RHOA mutations in adult T-cell leukemia/lymphoma.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
RecurrentRHOAmutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoB: Team Oncogene or Team Tumor Suppressor?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A landscape of driver mutations in melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAC1P29S is a spontaneously activating cancer-associated GTPase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Rac1 in a K-ras induced lung cancer in the mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P21 activated kinase signaling in cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 nucleocytoplasmic shuttling drives nuclear shape changes and tumor invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toward understanding RhoGTPase specificity: structure, function and local activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteomics. Tissue-based map of the human proteome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41388-019-0963-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/S41388-019-0963-7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
PubMed publication ID
31427738
1 reference
stated in
Europe PubMed Central
PubMed publication ID
31427738
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31427738%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 May 2020
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