(Q22242369)

2

Anastasios

Georgakopoulos

1 reference

28 March 2023

Pankaj Mehta

3

Pankaj

Mehta

1 reference

28 March 2023

Zen Kouchi

4

Zen

Kouchi

1 reference

28 March 2023

Claudia M. Litterst

5

Claudia M

Litterst

1 reference

28 March 2023

Lia Baki

6

Lia

Baki

1 reference

28 March 2023

Nikolaos K. Robakis

7

Nikolaos K

Journal of Neurochemistry

Robakis

1 reference

28 March 2023

language of work or name

English

0 references

publication date

17 November 2006

0 references

published in

0 references

volume

101

0 references

issue

3

0 references

page(s)

674-681

0 references

cites work

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

Quantification of sub-femtomole amounts of Alzheimer amyloid beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

An Alzheimer's disease hypothesis based on transcriptional dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

A novel presenilin 1 mutation associated with Pick's disease but not beta-amyloid plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Improved electrophoretic separation and immunoblotting of beta-amyloid (A beta) peptides 1-40, 1-42, and 1-43.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Neuropathological stageing of Alzheimer-related changes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Correlations of synaptic and pathological markers with cognition of the elderly

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Modeling clinically heterogeneous presenilin mutations with transgenic Drosophila

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Mean age of onset in familial Alzheimer's disease is determined by amyloid beta 42.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Alzheimer's disease: its proteins and genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Alzheimer's disease: a re-examination of the amyloid hypothesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Twenty-nine missense mutations linked with familial Alzheimer's disease alter the processing of presenilin 1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Enhancement of amyloid beta 42 secretion by 28 different presenilin 1 mutations of familial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Neurobiology: double trouble for neurons

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Alzheimer neuropathologic alterations in aged cognitively normal subjects.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of A beta precursors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Dementia with prominent frontotemporal features associated with L113P presenilin 1 mutation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021

Deletion of presenilin 1 hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04391.X

7 January 2021