(Q26830075)

author name string

Carmelo Antonio Caserta

series ordinal

3

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language of work or name

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15 September 2014

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International Journal of Cancer

published in

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volume

135

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issue

6

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page(s)

1265-76

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cites work

The Hallmarks of Cancer

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Intra-tumour heterogeneity: a looking glass for cancer?

21 January 2018

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EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

21 January 2018

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Epithelial-mesenchymal transitions in development and disease

21 January 2018

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Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

21 January 2018

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The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

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Generation of breast cancer stem cells through epithelial-mesenchymal transition

21 January 2018

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Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness

21 January 2018

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Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential

21 January 2018

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TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer

21 January 2018

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Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton

21 January 2018

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Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases.

21 January 2018

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Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis

21 January 2018

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TGFbeta-induced EMT requires focal adhesion kinase (FAK) signaling.

21 January 2018

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Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis

21 January 2018

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21 January 2018

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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

21 January 2018

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Interstitial fluid pressure and associated lymph node metastasis revealed in tumors by dynamic contrast-enhanced MRI.

21 January 2018

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Mechanical compression drives cancer cells toward invasive phenotype

21 January 2018

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Regulation of Epithelial-Mesenchymal Transition by Transmission of Mechanical Stress through Epithelial Tissues

21 January 2018

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Solid stress facilitates spheroid formation: potential involvement of hyaluronan.

21 January 2018

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Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules

21 January 2018

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Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

21 January 2018

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Matrix elasticity directs stem cell lineage specification

21 January 2018

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Gene expression profiles in 3D tumor analogs indicate compressive strain differentially enhances metastatic potential

21 January 2018

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Tensional homeostasis and the malignant phenotype

21 January 2018

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A tense situation: forcing tumour progression

21 January 2018

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Independent regulation of tumor cell migration by matrix stiffness and confinement.

21 January 2018

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Type I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1

21 January 2018

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Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling

21 January 2018

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Cytokines and Growth Factors Stimulate Hyaluronan Production: Role of Hyaluronan in Epithelial to Mesenchymal-Like Transition in Non-Small Cell Lung Cancer

21 January 2018

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Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemothera

21 January 2018

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Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.

21 January 2018

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HIF-1alpha determines the metastatic potential of gastric cancer cells

21 January 2018

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Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells

21 January 2018

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A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer.

21 January 2018

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Hypoxia-induced genetic instability--a calculated mechanism underlying tumor progression

21 January 2018

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Acidity generated by the tumor microenvironment drives local invasion

21 January 2018

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Acidic pH enhances the invasive behavior of human melanoma cells

21 January 2018

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Proton dynamics in cancer

21 January 2018

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Cisplatin treatment induces a transient increase in tumorigenic potential associated with high interleukin-6 expression in head and neck squamous cell carcinoma.

21 January 2018

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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

21 January 2018

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Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance

21 January 2018

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A CXCL1 paracrine network links cancer chemoresistance and metastasis

21 January 2018

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Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes

21 January 2018

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Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

21 January 2018

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Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

21 January 2018

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Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

21 January 2018

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Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

21 January 2018

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Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

21 January 2018

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Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype.

21 January 2018

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Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling

21 January 2018

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TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer

21 January 2018

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Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

21 January 2018

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Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

21 January 2018

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Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling

21 January 2018

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Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse

21 January 2018

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Interstitial flow in a 3D microenvironment increases glioma invasion by a CXCR4-dependent mechanism

21 January 2018

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How to improve exposure of tumor cells to drugs: promoter drugs increase tumor uptake and penetration of effector drugs.

21 January 2018

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Improving drug penetration to curb tumor drug resistance.

21 January 2018

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Approaches to improve tumor accumulation and interactions between monoclonal antibodies and immune cells

21 January 2018

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Collagen density promotes mammary tumor initiation and progression

21 January 2018

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Signaling pathways involved in collagen-induced disruption of the E-cadherin complex during epithelial-mesenchymal transition

21 January 2018

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Hyaluronan substratum induces multidrug resistance in human mesenchymal stem cells via CD44 signaling.

21 January 2018

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Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis

21 January 2018

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The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths

21 January 2018

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Regulation of cancer cell metabolism

21 January 2018

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Nox4 mediates renal cell carcinoma cell invasion through hypoxia-induced interleukin 6- and 8- production

21 January 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

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Targeting hypoxia in cancer therapy

21 January 2018

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Normalization of the vasculature for treatment of cancer and other diseases

21 January 2018

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Molecular mechanisms and clinical applications of angiogenesis

21 January 2018

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Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival

21 January 2018

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Targeting HIF-1 for cancer therapy

21 January 2018

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Hypoxia-inducible factors as key regulators of tumor inflammation

21 January 2018

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Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features

21 January 2018

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Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

21 January 2018

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Inhibition of p38 MAPK suppresses inflammatory cytokine induction by etoposide, 5-fluorouracil, and doxorubicin without affecting tumoricidal activity

21 January 2018

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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

21 January 2018

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

21 January 2018

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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

21 January 2018

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DAMPs, PAMPs and alarmins: all we need to know about danger

21 January 2018

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Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma

21 January 2018

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Three-dimensional context regulation of metastasis

21 January 2018

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IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway

21 January 2018

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Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

21 January 2018

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Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells

21 January 2018

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Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

21 January 2018

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Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

21 January 2018

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TGF-β-induced epithelial-mesenchymal transition of A549 lung adenocarcinoma cells is enhanced by pro-inflammatory cytokines derived from RAW 264.7 macrophage cells

21 January 2018

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Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase.

21 January 2018

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Hypoxia, gene expression, and metastasis

21 January 2018

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VEGF exerts an angiogenesis-independent function in cancer cells to promote their malignant progression

21 January 2018

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Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

21 January 2018

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Increased furin activity enhances the malignant phenotype of human head and neck cancer cells

21 January 2018

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Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

21 January 2018

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Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta

21 January 2018

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Environment-mediated drug resistance: a major contributor to minimal residual disease

21 January 2018

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The effects and mechanisms of blockage of STAT3 signaling pathway on IL-6 inducing EMT in human pancreatic cancer cells in vitro

21 January 2018

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Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1

21 January 2018

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NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

21 January 2018

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Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses.

21 January 2018

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Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators.

21 January 2018

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Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

21 January 2018

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Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1.

21 January 2018

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S100A8/A9 activate key genes and pathways in colon tumor progression

21 January 2018

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The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

21 January 2018

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Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells.

21 January 2018

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Chemotherapeutic drugs and human tumor cells cytokine network

21 January 2018

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Modulation of myoepithelial-associated alpha6beta4 integrin in a breast cancer cell line alters invasive potential

21 January 2018

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Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer.

21 January 2018

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Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

21 January 2018

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Matrix crosslinking forces tumor progression by enhancing integrin signaling

21 January 2018

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Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment

21 January 2018

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Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis

21 January 2018

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Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity

21 January 2018

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E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors

21 January 2018

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Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation

21 January 2018

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Autophagy controls p38 activation to promote cell survival under genotoxic stress

21 January 2018

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Cell proliferation of cultured human cancer cells are affected by the elevated tumor pressures that exist in vivo

21 January 2018

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Micro-environmental mechanical stress controls tumor spheroid size and morphology by suppressing proliferation and inducing apoptosis in cancer cells

21 January 2018

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Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.

21 January 2018

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p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death.

21 January 2018

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Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma

21 January 2018

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

21 January 2018

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Autophagy is a protective mechanism for human melanoma cells under acidic stress

21 January 2018

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

21 January 2018

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Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

21 January 2018

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The Hedgehog signalling pathway regulates autophagy.

21 January 2018

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AMP-activated protein kinase inhibits TGF-β-, angiotensin II-, aldosterone-, high glucose-, and albumin-induced epithelial-mesenchymal transition

21 January 2018

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Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells

21 January 2018

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The dawn of hedgehog inhibitors: Vismodegib

21 January 2018

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The landscape of somatic copy-number alteration across human cancers

21 January 2018

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Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis

21 January 2018

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A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs

21 January 2018

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

21 January 2018

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

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Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors.

21 January 2018

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PI3 kinase/Akt/HIF-1α pathway is associated with hypoxia-induced epithelial-mesenchymal transition in fibroblast-like synoviocytes of rheumatoid arthritis.

21 January 2018

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Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation

21 January 2018

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Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein

21 January 2018

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Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress

21 January 2018

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Oncostatin m modulates the mesenchymal-epithelial transition of lung adenocarcinoma cells by a mesenchymal stem cell-mediated paracrine effect

21 January 2018

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A cell-based small molecule screening method for identifying inhibitors of epithelial-mesenchymal transition in carcinoma

21 January 2018

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Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids

21 January 2018

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Elevated expression of vacuolar proton pump genes and cellular PH in cisplatin resistance

21 January 2018

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7 January 2021

Mesenchymal stem cells enhance growth and metastasis of colon cancer

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7 January 2021

Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells

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7 January 2021

Solid stress inhibits the growth of multicellular tumor spheroids

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7 January 2021

Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

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7 January 2021

Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion

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7 January 2021

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7 January 2021

Hypoxia-inducible factor–dependent breastcancer–mesenchymal stem cell bidirectional signaling promotesmetastasis.

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7 January 2021

HMGB1 induces the overexpression of miR-222 and miR-221 and increases growth and motility in papillary thyroid cancer cells

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7 January 2021

Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo

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7 January 2021