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Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention
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PubMed
title
Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention
(English)
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stated in
PubMed
main subject
Alzheimer's disease
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based on heuristic
inferred from title
author
Sandra M. Cardoso
object named as
Sandra M. Cardoso
series ordinal
5
0 references
Russell H Swerdlow
series ordinal
6
object named as
Russell H. Swerdlow
1 reference
stated in
Crossref
author name string
Diana F. Silva
series ordinal
1
1 reference
stated in
Crossref
J. Eva Selfridge
series ordinal
2
1 reference
stated in
Crossref
Jianghua Lu
series ordinal
3
1 reference
stated in
Crossref
Lezi E
series ordinal
4
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
2012
1 reference
stated in
PubMed
published in
Advances in Pharmacology
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stated in
PubMed
volume
64
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stated in
PubMed
page(s)
83-126
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stated in
PubMed
cites work
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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
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Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport
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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
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S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
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28 September 2017
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28 September 2017
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28 September 2017
Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death
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28 September 2017
Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease
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28 September 2017
Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons
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28 September 2017
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28 September 2017
Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
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28 September 2017
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients
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28 September 2017
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
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28 September 2017
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28 September 2017
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28 September 2017
The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?
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28 September 2017
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: implications for the role of nitration in the progression of Alzheimer's disease.
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28 September 2017
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28 September 2017
The thiazolidinedione pioglitazone alters mitochondrial function in human neuron-like cells
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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31 May 2018
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31 May 2018
Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis.
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31 May 2018
Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers
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31 May 2018
Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment
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31 May 2018
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.
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31 May 2018
Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease
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31 May 2018
Oxidative state in platelets and erythrocytes in aging and Alzheimer's disease
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31 May 2018
Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons.
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31 May 2018
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
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31 May 2018
Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer's disease
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31 May 2018
Relationship between DNA fragmentation, morphological changes and neuronal loss in Alzheimer's disease and dementia with Lewy bodies.
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31 May 2018
The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease
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31 May 2018
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31 May 2018
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
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31 May 2018
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31 May 2018
Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease
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31 May 2018
Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients
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31 May 2018
Elevated levels of the Kearns-Sayre syndrome mitochondrial DNA deletion in temporal cortex of Alzheimer's patients
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31 May 2018
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31 May 2018
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31 May 2018
Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease.
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31 May 2018
In situ labeling of dying cortical neurons in normal aging and in Alzheimer's disease: correlations with senile plaques and disease progression.
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31 May 2018
Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxidase deficiency.
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31 May 2018
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31 May 2018
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31 May 2018
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31 May 2018
Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias.
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31 May 2018
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type
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31 May 2018
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31 May 2018
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis
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28 November 2018
NAP prevents acute cerebral oxidative stress and protects against long-term brain injury and cognitive impairment in a model of neonatal hypoxia-ischemia.
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28 November 2018
Peripheral oxidative stress biomarkers in mild cognitive impairment and Alzheimer's disease.
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28 November 2018
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28 November 2018
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28 November 2018
Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer's disease: insights into memory loss in MCI.
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28 November 2018
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28 November 2018
Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease.
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28 November 2018
Effects of ageing and Alzheimer's disease on mitochondrial function of human platelets
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28 November 2018
Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer's disease from Mild Cognitive Impairment
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28 November 2018
NAP, a neuroprotective drug candidate in clinical trials, stimulates microtubule assembly in the living cell
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28 November 2018
A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer's Disease
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28 November 2018
Activity-dependent neuroprotective protein snippet NAP reduces tau hyperphosphorylation and enhances learning in a novel transgenic mouse model.
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28 November 2018
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28 November 2018
Correlations of disability and biologic alterations in Alzheimer brain and test of significance by a therapeutic trial in humans.
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28 November 2018
Caspase-3 cleaved spectrin colocalizes with neurofilament-immunoreactive neurons in Alzheimer's disease
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease
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28 November 2018
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28 November 2018
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28 November 2018
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28 November 2018
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Methylene blue improves brain oxidative metabolism and memory retention in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Cytochrome c oxidase is decreased in Alzheimer's disease platelets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Idebenone treatment fails to slow cognitive decline in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Quantitative assessment of DNA fragmentation and beta-amyloid deposition in insular cortex and midfrontal gyrus from patients with Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Impaired axonal transport of cortical neurons in Alzheimer's disease is associated with neuropathological changes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Activation of caspase-8 in the Alzheimer's disease brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Oxidative damage is the earliest event in Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Mitochondrial abnormalities in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Elevated levels of fragmented DNA nucleosomes in native and activated lymphocytes indicate an enhanced sensitivity to apoptosis in sporadic Alzheimer's disease. Specific differences to vascular dementia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
The frequency of point mutations in mitochondrial DNA is elevated in the Alzheimer's brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Abnormalities of mitochondrial enzymes in Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Increased nuclear DNA oxidation in the brain in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Oxidative damage to DNA in lymphocytes from AD patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
The lipid peroxidation product, 4-hydroxy-2-trans-nonenal, alters the conformation of cortical synaptosomal membrane proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
A controlled study of 2 doses of idebenone in the treatment of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde".
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Functional alterations in Alzheimer's disease: diminution of cytochrome oxidase in the hippocampal formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Immunohistochemical evidence for apoptosis in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Evidence for apoptotic cell death in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625400
retrieved
28 November 2018
Cytochrome oxidase deficiency in Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22840745
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Marked changes in mitochondrial DNA deletion levels in Alzheimer brains
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22840745
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22840745
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22840745
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22840745
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/B978-0-12-394816-8.00003-9
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2481746
OpenCitations bibliographic resource ID
2481746
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2481746
PMC publication ID
3625400
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2481746
PubMed publication ID
22840745
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2481746
ResearchGate publication ID
230575886
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