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Autophagy and neurodegeneration
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2 references
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PubMed
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Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
review article
1 reference
stated in
Europe PubMed Central
title
Autophagy and neurodegeneration
(English)
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
main subject
autophagy
0 references
author
Rebecca A Frake
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
author name string
Thomas Ricketts
series ordinal
2
2 references
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Crossref
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Fiona M Menzies
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
David C Rubinsztein
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4
1 reference
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Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
language of work or name
English
1 reference
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PubMed
publication date
2 January 2015
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Europe PubMed Central
PMCID
4382230
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
published in
Journal of Clinical Investigation
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
volume
125
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
issue
1
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
page(s)
65-74
2 references
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PubMed
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
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21 March 2017
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21 March 2017
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21 March 2017
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21 March 2017
Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration
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21 March 2017
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
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21 March 2017
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
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21 March 2017
Identification of a candidate therapeutic autophagy-inducing peptide
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21 March 2017
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice
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7 April 2017
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
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7 April 2017
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
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7 April 2017
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
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7 April 2017
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.
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28 September 2017
Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy
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28 September 2017
Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease
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28 September 2017
MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis.
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28 September 2017
Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP
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28 September 2017
Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance
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28 September 2017
Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy
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28 September 2017
Defective autophagy in spastizin mutated patients with hereditary spastic paraparesis type 15
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28 September 2017
Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease
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28 September 2017
IGF-1 receptor antagonism inhibits autophagy
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28 September 2017
Induction of autophagy by a novel small molecule improves aβ pathology and ameliorates cognitive deficits
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28 September 2017
Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation
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28 September 2017
mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.
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28 September 2017
The genetics of Parkinson's disease: progress and therapeutic implications
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28 September 2017
Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson's disease
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28 September 2017
Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy.
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28 September 2017
Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
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PubMed Central
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28 September 2017
Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis
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PubMed Central
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28 September 2017
Exome sequencing reveals de novo WDR45 mutations causing a phenotypically distinct, X-linked dominant form of NBIA.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382230
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28 September 2017
Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382230
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28 September 2017
Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382230
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28 September 2017
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43
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28 September 2017
Mitophagy and Parkinson's disease: be eaten to stay healthy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382230
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28 September 2017
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28 September 2017
Deciphering the role of malin in the lafora progressive myoclonus epilepsy
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28 September 2017
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
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28 September 2017
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28 September 2017
A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway
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28 September 2017
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
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28 September 2017
Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy
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28 September 2017
Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.
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28 September 2017
AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.
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28 September 2017
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
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28 September 2017
TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease
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28 September 2017
Hyperphosphorylation and aggregation of Tau in laforin-deficient mice, an animal model for Lafora disease.
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28 September 2017
The effects of dynein inhibition on the autophagic pathway in glioma cells
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28 September 2017
DCTN1 mutations in Perry syndrome
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28 September 2017
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
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28 September 2017
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
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28 September 2017
Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
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28 September 2017
Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes
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28 September 2017
Autophagy plays a protective role during zVAD-induced necrotic cell death.
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28 September 2017
Earliest stages of tau conformational changes are related to the appearance of a sequence of specific phospho-dependent tau epitopes in Alzheimer's disease.
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28 September 2017
The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes
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28 September 2017
Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo.
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28 September 2017
Small molecule regulators of autophagy identified by an image-based high-throughput screen
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28 September 2017
Advances in lafora progressive myoclonus epilepsy
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28 September 2017
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
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28 September 2017
Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases.
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28 September 2017
Deleterious and protective properties of an aggregate-prone protein with a polyalanine expansion
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28 September 2017
Model-guided microarray implicates the retromer complex in Alzheimer's disease
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28 September 2017
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
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28 September 2017
Lithium induces autophagy by inhibiting inositol monophosphatase
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28 September 2017
Dynein mutations impair autophagic clearance of aggregate-prone proteins
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28 September 2017
Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone
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28 September 2017
TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.
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28 September 2017
Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy
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28 September 2017
Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models
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31 May 2018
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
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31 May 2018
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo.
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31 May 2018
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.
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31 May 2018
Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation
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31 May 2018
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
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31 May 2018
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
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31 May 2018
Autophagosome-like vacuole formation in Huntington's disease lymphoblasts
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31 May 2018
Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease.
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28 November 2018
Advances in motor neurone disease.
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28 November 2018
Aβ secretion and plaque formation depend on autophagy
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28 November 2018
Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance
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28 November 2018
Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons
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28 November 2018
Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology
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28 November 2018
Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease.
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28 November 2018
Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington's, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease
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28 November 2018
Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.
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28 November 2018
Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: implications of autophagy promotion
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28 November 2018
Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy
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28 November 2018
Autophagic degradation of tau in primary neurons and its enhancement by trehalose.
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28 November 2018
Optineurin in Huntington's disease intranuclear inclusions
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28 November 2018
Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.
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28 November 2018
The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes.
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28 November 2018
Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7.
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28 November 2018
A comparison of huntington disease and huntington disease-like 2 neuropathology
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28 November 2018
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.
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28 November 2018
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
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28 November 2018
AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis
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28 November 2018
Rapamycin pre-treatment protects against apoptosis
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28 November 2018
Rapamycin alleviates toxicity of different aggregate-prone proteins
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28 November 2018
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.
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28 November 2018
Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology.
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28 November 2018
α-Synuclein Is Degraded by Both Autophagy and the Proteasome
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382230
retrieved
28 November 2018
Mutant dynactin in motor neuron disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382230
retrieved
28 November 2018
Mutations in the gene encoding p62 in Japanese patients with amyotrophic lateral sclerosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25654552
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25654552
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI73944
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913838
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Fatcat ID
release_kol6r32acnchxdlm3g5hokrq2y
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/kol6r32acnchxdlm3g5hokrq2y
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
913838
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913838
PMCID
4382230
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913838
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed ID
25654552
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913838
stated in
Europe PubMed Central
PMCID
4382230
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25654552%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
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