(Q27004080)

Xiao Wen Lee

series ordinal

2

1 reference

Xueying Wang

series ordinal

3

1 reference

language of work or name

1 reference

July 2013

1 reference

1 reference

280

1 reference

PubMed

issue

14

1 reference

PubMed

page(s)

3180-93

1 reference

DNA damage response at functional and dysfunctional telomeres

PubMed

cites work

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Protection of mammalian telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

X-linked dyskeratosis congenita is predominantly caused by missense mutations in the DKC1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomerase and idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere shortening in familial and sporadic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomerase mutations in families with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Accelerated telomere shortening in Fanconi anemia fibroblasts--a longitudinal study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

FANCC suppresses short telomere-initiated telomere sister chromatid exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Abnormal telomere metabolism in Fanconi's anaemia correlates with genomic instability and the probability of developing severe aplastic anaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere dynamics in Fancg-deficient mouse and human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

A role for monoubiquitinated FANCD2 at telomeres in ALT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Accelerated in vivo epidermal telomere loss in Werner syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere dysfunction as a cause of genomic instability in Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Hyper telomere recombination accelerates replicative senescence and may promote premature aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Essential role of limiting telomeres in the pathogenesis of Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Clinical features of Bloom syndrome and function of the causative gene, BLM helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The Bloom's syndrome gene product promotes branch migration of holliday junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Binding and melting of D-loops by the Bloom syndrome helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Atm-deficient mice: a paradigm of ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Influence of ATM function on interactions between telomeres and nuclear matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

A murine model of Nijmegen breakage syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The Nijmegen breakage syndrome gene and its role in genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The mre11 complex and the response to dysfunctional telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Multiple roles for MRE11 at uncapped telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Mre11 modulates the fidelity of fusion between short telomeres in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Differential regulation of MRN (Mre11–Rad50–Nbs1) complex subunits and telomerase activity in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Leukocyte telomere length and mortality in the Cardiovascular Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The role of DNA damage response proteins at telomeres--an "integrative" model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere attrition and Chk2 activation in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Chromosomal instability in ulcerative colitis is related to telomere shortening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

GERD is associated with shortened telomeres in the squamous epithelium of the distal esophagus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Association of shorter leukocyte telomere repeat length with dementia and mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere length is age-dependent and reduced in monocytes of Alzheimer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere shortening in T cells correlates with Alzheimer's disease status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4+ T Cell Turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Cytomegalovirus infection reduces telomere length of the circulating T cell pool.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere length in Hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

The flow cytometric analysis of telomere length in antigen-specific CD8+ T cells during acute Epstein-Barr virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

In situ analyses of genome instability in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326

Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12326