(Q27308125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

A Cell Biologist's Field Guide to Aurora Kinase Inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Christian O de Groot

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Judy E Hsia

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

John V Anzola

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Amir Motamedi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Michelle Yoon

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

David Jenkins

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Hyun J Lee

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Mallory B Martinez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Robert L Davis

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Timothy C Gahman

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Arshad Desai

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Andrew K Shiau

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

English

0 references

publication date

21 December 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

published in

Frontiers in Oncology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

4 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4685510/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Drugging MYCN through an allosteric transition in Aurora kinase A

21 March 2017

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Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2

21 March 2017

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21 March 2017

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Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors

21 March 2017

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Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells

21 March 2017

1 reference

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Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma

21 March 2017

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Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

21 March 2017

1 reference

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Selective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity Screen

21 March 2017

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Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2

21 March 2017

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Phthalazinone pyrazoles as potent, selective, and orally bioavailable inhibitors of Aurora-A kinase

21 March 2017

1 reference

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Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Drug-resistant aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237

21 March 2017

1 reference

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 March 2017

1 reference

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Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design

21 March 2017

1 reference

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A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B

21 March 2017

1 reference

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Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Modulation of kinase-inhibitor interactions by auxiliary protein binding: crystallography studies on Aurora A interactions with VX-680 and with TPX2

21 March 2017

1 reference

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Molecular basis of drug resistance in aurora kinases

21 March 2017

1 reference

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Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

21 March 2017

1 reference

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Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

21 March 2017

1 reference

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Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography

21 March 2017

1 reference

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Crystal structure of aurora-2, an oncogenic serine/threonine kinase

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Human TPX2 is required for targeting Aurora-A kinase to the spindle

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 March 2017

1 reference

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Phasercrystallographic software

21 March 2017

1 reference

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 March 2017

1 reference

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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Processing of X-ray diffraction data collected in oscillation mode

21 March 2017

1 reference

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Chromosomal passengers: conducting cell division

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The promise and peril of chemical probes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The ABC of protein kinase conformations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora kinase A inhibitors: promising agents in antitumoral therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The aurora kinases in cell cycle and leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The structural mechanisms that underpin mitotic kinase activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora A kinase (AURKA) in normal and pathological cell division

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Cell division control by the Chromosomal Passenger Complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora kinase inhibitors: progress towards the clinic

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Activation of Aurora-A kinase by protein partner binding and phosphorylation are independent and synergistic

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

A novel cell-based, high-content assay for phosphorylation of Lats2 by Aurora A.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Probing the probes: fitness factors for small molecule tools

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Phase 1 study of MLN8054, a selective inhibitor of Aurora A kinase in patients with advanced solid tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

3-Cyano-6-(5-methyl-3-pyrazoloamino)pyridines: selective Aurora A kinase inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora-C kinase deficiency causes cytokinesis failure in meiosis I and production of large polyploid oocytes in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

MLN8054, an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The challenge of selecting protein kinase assays for lead discovery optimization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The discovery of the potent aurora inhibitor MK-0457 (VX-680).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Discovery and development of aurora kinase inhibitors as anticancer agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Quantitative analysis of cell cycle phase durations and PC12 differentiation using fluorescent biosensors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The catalytic role of INCENP in Aurora B activation and the kinetic mechanism of Aurora B/INCENP.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Polo and Aurora kinases: lessons derived from chemical biology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora A, mitotic entry, and spindle bipolarity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora-A site specificity: a study with synthetic peptide substrates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Features of selective kinase inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Mechanism of Aurora B activation by INCENP and inhibition by hesperadin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Dynamics of DNA replication factories in living cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Monoclonal antibodies to mitotic cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Evaluation of methods for estimating the dissociation constant of tight binding enzyme inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Phase I assessment of new mechanism-based pharmacodynamic biomarkers for MLN8054, a small-molecule inhibitor of Aurora A kinase

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Tight-binding inhibitors-II. Non-steady state nature of inhibition of milk xanthine oxidase by allopurinol and alloxanthine and of human erythrocytic adenosine deaminase by coformycin

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685510

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

31 May 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Gene expression profiles of the aurora family kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

A kinetic test characterizes kinase intramolecular and intermolecular autophosphorylation mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Phase I study of aurora A kinase inhibitor MLN8237 in advanced solid tumors: safety, pharmacokinetics, pharmacodynamics, and bioavailability of two oral formulations

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Studies on cholinesterase. 7. Determination of the molar concentration of pseudo-cholinesterase in serum

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Long residence times revealed by Aurora A kinase-targeting fluorescent probes derived from inhibitors MLN8237 and VX-689.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Phosphorylation of maskin by Aurora-A participates in the control of sequential protein synthesis during Xenopus laevis oocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Erratum: Corrigendum: The promise and peril of chemical probes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants for the analysis of mitotic networks

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2015.00285

Mitotic kinase expression and colorectal cancer progression

21 January 2018

1 reference

12 December 2020

A novel mechanism for activation of the protein kinase Aurora A

1 reference

12 December 2020

Regulation ofXenopusAurora A Activation by TPX2

1 reference

12 December 2020

Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies

1 reference

12 December 2020

Differential Functions of the Aurora-B and Aurora-C Kinases in Mammalian Spermatogenesis

1 reference

12 December 2020

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

1 reference

12 December 2020

Binding of TPX2 to Aurora A alters substrate and inhibitor interactions

1 reference

12 December 2020

Identifiers

DOI

10.3389/FONC.2015.00285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

26732741

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732741%20AND%20SRC:MED&resulttype=core&format=json