(Q27678084)

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Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design

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scholarly article

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Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design (English)

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crystal structure

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Plasmodium falciparum

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tryptophan--tRNA ligase

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11 September 2018

tryptophan--tRNA ligase

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11 September 2018

tryptophan--tRNA ligase, putative

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25 September 2018

tryptophan--tRNA ligase, putative

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25 September 2018

tryptophan--tRNA ligase, putative

1 reference

15 December 2018

tryptophan--tRNA ligase, putative

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15 December 2018

tryptophan--tRNA ligase, putative

1 reference

19 December 2018

tryptophan--tRNA ligase, putative

1 reference

19 December 2018

tryptophan--tRNA ligase, putative

1 reference

19 December 2018

tryptophan--tRNA ligase, putative

1 reference

19 December 2018

tryptophan--tRNA ligase, putative

1 reference

20 December 2018

tryptophan--tRNA ligase, putative

1 reference

20 December 2018

tryptophan--tRNA ligase, putative

1 reference

20 December 2018

tryptophan--tRNA ligase, putative

1 reference

21 December 2018

tryptophan--tRNA ligase, putative

1 reference

21 December 2018

tryptophan--tRNA ligase, putative

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tryptophan--tRNA ligase, putative

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Wesley C Van Voorhis

7

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object named as

Cho Yeow Koh

1

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Frederick S Buckner

6

object named as

Frederick S Buckner

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8

object named as

Wim G J Hol

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author name string

Jessica E Kim

2

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Alberto J Napoli

3

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Christophe L M J Verlinde

4

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Erkang Fan

5

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publication date

May 2013

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Molecular and Biochemical Parasitology

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189

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1-2

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26-32

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Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design

1 reference

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1 reference

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Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

1 reference

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20 March 2017

Structure of the prolyl-tRNA synthetase from the eukaryotic pathogenGiardia lamblia

1 reference

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Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection

1 reference

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Global malaria mortality between 1980 and 2010: a systematic analysis

1 reference

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The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer

1 reference

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20 March 2017

Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase

1 reference

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20 March 2017

Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate

1 reference

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20 March 2017

The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs

1 reference

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20 March 2017

Artemisinin resistance: current status and scenarios for containment

1 reference

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20 March 2017

Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs

1 reference

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20 March 2017

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

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20 March 2017

Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica

1 reference

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20 March 2017

Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680109

20 March 2017

Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680109

20 March 2017

Functional and Crystal Structure Analysis of Active Site Adaptations of a Potent Anti-Angiogenic Human tRNA Synthetase

1 reference

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20 March 2017

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

1 reference

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20 March 2017

Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains

1 reference

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20 March 2017

Crystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680109

20 March 2017

Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations

1 reference

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20 March 2017

Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography

1 reference

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20 March 2017

2.9 Å crystal structure of ligand-free tryptophanyl-tRNA synthetase: Domain movements fragment the adenine nucleotide binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680109

20 March 2017

Dali server: conservation mapping in 3D

1 reference

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20 March 2017

1 reference

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20 March 2017

Phasercrystallographic software

1 reference

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20 March 2017

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

1 reference

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20 March 2017

Inference of macromolecular assemblies from crystalline state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680109

20 March 2017

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues

1 reference

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20 March 2017

Coot: model-building tools for molecular graphics

1 reference

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20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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20 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

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20 March 2017

ESPript/ENDscript: Extracting and rendering sequence and 3D information from atomic structures of proteins

1 reference

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20 March 2017

Aminoacyl-tRNA synthesis

1 reference

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7 April 2017

Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization.

1 reference

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29 September 2017

Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin

1 reference

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1 reference

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Protein translation in Plasmodium parasites.

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29 September 2017

Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice

1 reference

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29 September 2017

Structure of human tryptophanyl-tRNA synthetase in complex with tRNATrp reveals the molecular basis of tRNA recognition and specificity.

1 reference

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29 September 2017

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1 reference

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1 reference

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Global health. Disappointing results blunt hopes for malaria vaccine

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27 November 2018

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1 reference

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Allosteric inhibition of protein tyrosine phosphatase 1B.

1 reference

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27 November 2018

Identifiers

10.1016/J.MOLBIOPARA.2013.04.007

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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