(Q27713462)

5

0 references

Yanxin Liu

object named as

Yanxin Liu

4

0 references

Shigeyuki Yokoyama

object named as

Shigeyuki Yokoyama

6

0 references

Akihiko Arakawa

3

object named as

Akihiko Arakawa

0 references

author name string

Kliment A Verba

1

0 references

Ray Yu-Ruei Wang

2

0 references

David A Agard

Glucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cycles

7

0 references

language of work or name

English

0 references

publication date

24 June 2016

0 references

published in

Science

0 references

volume

352

0 references

page(s)

1542-7

0 references

issue

6293

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Structural Asymmetry in the Closed State of Mitochondrial Hsp90 (TRAP1) Supports a Two-Step ATP Hydrolysis Mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Crystal structure of human CDK4 in complex with a D-type cyclin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

The structure of CDK4/cyclin D3 has implications for models of CDK activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice

7 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAF5023

EMAN2: an extensible image processing suite for electron microscopy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAF5023

UCSF Chimera--a visualization system for exploratory research and analysis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAF5023

Conventions and workflows for using Situs

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAF5023

Scalable molecular dynamics with NAMD

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAF5023

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAF5023

Features and development of Coot

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAF5023

Targeting cancer with small molecule kinase inhibitors

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

RELION: implementation of a Bayesian approach to cryo-EM structure determination

7 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics

7 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90.

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Single-Particle Cryo-EM at Crystallographic Resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Hsp90: breaking the symmetry.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Phosphorylated and unphosphorylated serine 13 of CDC37 stabilize distinct interactions between its client and HSP90 binding domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Hsp90 promotes kinase evolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Transitions to catalytically inactive conformations in EGFR kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Uncovering a region of heat shock protein 90 important for client binding in E. coli and chaperone function in yeast.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

The therapeutic target Hsp90 and cancer hallmarks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Evolution of the eukaryotic protein kinases as dynamic molecular switches

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

The structural basis for control of eukaryotic protein kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Conformational dynamics of the molecular chaperone Hsp90

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Structure of an Hsp90-Cdc37-Cdk4 complex.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This Complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Hsp90·Cdc37 Complexes with Protein Kinases Form Cooperatively with Multiple Distinct Interaction Sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Cdc37 (cell division cycle 37) restricts Hsp90 (heat shock protein 90) motility by interaction with N-terminal and middle domain binding sites

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5373496

Functional Dissection of Cdc37: Characterization of Domain Structure and Amino Acid Residues Critical for Protein Kinase Binding

2 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

CTFFIND4: Fast and accurate defocus estimation from electron micrographs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

Beam-induced motion correction for sub-megadalton cryo-EM particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

Sampling the conformational space of the catalytic subunit of human γ-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

CATH: comprehensive structural and functional annotations for genome sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

De novo protein structure determination from near-atomic-resolution cryo-EM maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

High-resolution comparative modeling with RosettaCM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF5023

Molybdate inhibits hsp90, induces structural changes in its C-terminal domain, and alters its interactions with substrates

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27339980