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mTOR inhibitors in cancer therapy
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
mTOR inhibitors in cancer therapy
(English)
1 reference
stated in
PubMed
author
Jianling Xie
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
Christopher G. Proud
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
author name string
Xuemin Wang
series ordinal
2
2 references
stated in
Crossref
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
language of work or name
English
1 reference
stated in
PubMed
publication date
25 August 2016
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PubMed
published in
F1000Research
2 references
stated in
Crossref
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
volume
5
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
copyright license
Creative Commons Attribution 4.0 International
start time
25 August 2016
1 reference
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April 2022 Public Data File from Crossref
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mTOR kinase inhibition causes feedback-dependent biphasic regulation of AKT signaling
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Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1
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29 September 2017
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29 September 2017
Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells
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29 September 2017
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29 September 2017
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.
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Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets
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29 September 2017
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29 September 2017
SDZ RAD, a new rapamycin derivative: pharmacological properties in vitro and in vivo
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29 September 2017
Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization
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29 September 2017
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity
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27 November 2018
Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007757
retrieved
27 November 2018
Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: the discovery of AZD8055 and AZD2014.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007757
retrieved
27 November 2018
Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007757
retrieved
27 November 2018
Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007757
retrieved
27 November 2018
The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007757
retrieved
27 November 2018
Rapamycin inhibits mTORC1, but not completely.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007757
retrieved
27 November 2018
Drosophila S6 kinase: a regulator of cell size
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007757
retrieved
27 November 2018
Sirolimus is associated with reduced islet engraftment and impaired beta-cell function
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27635236
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SDZ RAD, a new rapamycin derivative: synergism with cyclosporine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27635236
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tuberous sclerosis complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27635236
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.
1 reference
stated in
COCI
retrieved
12 April 2024
reference URL
https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.28.727
Identifiers
DOI
10.12688/F1000RESEARCH.9207.1
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3881345
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
OpenCitations bibliographic resource ID
3881345
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3881345
PMCID
5007757
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3881345
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
PubMed ID
27635236
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3881345
stated in
Europe PubMed Central
PMCID
5007757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27635236%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
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