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Organs-on-chips at the frontiers of drug discovery
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
Organs-on-chips at the frontiers of drug discovery
(English)
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stated in
PubMed
main subject
drug discovery
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author name string
Eric W. Esch
series ordinal
1
1 reference
stated in
Crossref
Anthony Bahinski
series ordinal
2
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stated in
Crossref
Dongeun Huh
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
April 2015
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stated in
PubMed
published in
Nature Reviews Drug Discovery
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stated in
PubMed
volume
14
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stated in
PubMed
issue
4
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stated in
PubMed
page(s)
248-60
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PubMed
cites work
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Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells.
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The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline
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Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and Its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips
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Building and manipulating neural pathways with microfluidics
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Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human
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27 November 2018
Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro.
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Astrocyte-neuron co-culture on microchips based on the model of SOD mutation to mimic ALS.
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27 November 2018
Characterization of drug permeability in Caco-2 monolayers by mass spectrometry on a membrane-based microfluidic device
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Human genetic variation of CYP450 superfamily: analysis of functional diversity in worldwide populations.
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27 November 2018
Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips.
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Advances in the preclinical testing of cancer therapeutic hypotheses.
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27 November 2018
A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip
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Micro total bioassay system for oral drugs: evaluation of gastrointestinal degradation, intestinal absorption, hepatic metabolism, and bioactivity
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Rare diseases and orphan drugs
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Comparison of Biocompatibility and Adsorption Properties of Different Plastics for Advanced Microfluidic Cell and Tissue Culture Models
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Identifiers
DOI
10.1038/NRD4539
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
202036
OpenCitations bibliographic resource ID
202036
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
202036
PMC publication ID
4826389
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
202036
PubMed publication ID
25792263
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
202036
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