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The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels
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Europe PubMed Central
PMC publication ID
3183054
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
title
The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels
(English)
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Europe PubMed Central
PMC publication ID
3183054
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
author
Mattias Vesterlund
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1
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PMC publication ID
3183054
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
Michael Lund Nielsen
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4
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3183054
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
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14 February 2020
Benedikt M. Kessler
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5
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14 February 2020
Gunnar Norstedt
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6
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14 February 2020
Amilcar Flores-Morales
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7
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Europe PubMed Central
PMC publication ID
3183054
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14 February 2020
Fahad Zadjali
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2
object named as
Fahad Zadjali
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Europe PubMed Central
PMC publication ID
3183054
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14 February 2020
author name string
Torbjörn Persson
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3
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Europe PubMed Central
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3183054
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
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14 February 2020
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publication date
29 September 2011
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Europe PubMed Central
PMC publication ID
3183054
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
published in
PLOS One
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Europe PubMed Central
PMC publication ID
3183054
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
volume
6
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Europe PubMed Central
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3183054
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14 February 2020
issue
9
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Europe PubMed Central
PMC publication ID
3183054
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
page(s)
e25358
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Europe PubMed Central
PMC publication ID
3183054
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
copyright license
Creative Commons Attribution 4.0 International
start time
29 September 2011
1 reference
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April 2022 Public Data File from Crossref
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0 references
cites work
Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase
1 reference
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SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation
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19 March 2017
The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin Ligase
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19 March 2017
Mammalian protein-protein interaction trap (MAPPIT) analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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19 March 2017
Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent
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19 March 2017
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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19 March 2017
SOCS2 negatively regulates growth hormone action in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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19 March 2017
Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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19 March 2017
Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene
1 reference
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19 March 2017
Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)
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PubMed Central
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19 March 2017
Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase
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19 March 2017
Gigantism in mice lacking suppressor of cytokine signalling-2
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19 March 2017
Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C
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PubMed Central
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19 March 2017
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
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PubMed Central
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19 March 2017
Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function
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PubMed Central
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19 March 2017
Socs2 and elf5 mediate prolactin-induced mammary gland development
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19 March 2017
Suppressor of cytokine signaling 2 regulates neuronal differentiation by inhibiting growth hormone signaling
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PubMed Central
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19 March 2017
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo
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PubMed Central
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19 March 2017
pEF-BOS, a powerful mammalian expression vector
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PubMed Central
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7 April 2017
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
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7 April 2017
The effect of GH and IGF1 on linear growth and skeletal development and their modulation by SOCS proteins.
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Suppressor of cytokine signaling 2 regulates IL-15-primed human NK cell function via control of phosphorylated Pyk2.
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29 September 2017
SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation.
1 reference
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29 September 2017
Growth hormone and bone
1 reference
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PubMed Central
reference URL
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29 September 2017
The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression
1 reference
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29 September 2017
Meta-analysis approach identifies candidate genes and associated molecular networks for type-2 diabetes mellitus
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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29 September 2017
Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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29 September 2017
Autocrine growth hormone: effects on growth hormone receptor trafficking and signaling
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PubMed Central
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29 September 2017
The ubiquitin ligase SCF(betaTrCP) regulates the degradation of the growth hormone receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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29 September 2017
Determinants of growth hormone receptor down-regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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29 September 2017
Suppressor of cytokine signaling (SOCS) 2, a protein with multiple functions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
In vivo transcript profiling and phylogenetic analysis identifies suppressor of cytokine signaling 2 as a direct signal transducer and activator of transcription 5b target in liver.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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29 September 2017
A complex interaction pattern of CIS and SOCS2 with the leptin receptor
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
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29 September 2017
Ubiquitin system-dependent regulation of growth hormone receptor signal transduction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
Suppressor of cytokine signaling-2 deficiency induces molecular and metabolic changes that partially overlap with growth hormone-dependent effects.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
Are SOCS suppressors, regulators, and degraders?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
29 September 2017
SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3183054
retrieved
27 November 2018
Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21980433
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Endocytosis and degradation of the growth hormone receptor are proteasome-dependent
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21980433
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PONE.0025358
1 reference
stated in
Europe PubMed Central
PMC publication ID
3183054
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
ADS bibcode
2011PLoSO...625358V
0 references
PMC publication ID
3183054
1 reference
stated in
Europe PubMed Central
PMC publication ID
3183054
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
PubMed publication ID
21980433
1 reference
stated in
Europe PubMed Central
PMC publication ID
3183054
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21980433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 February 2020
ResearchGate publication ID
51700098
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