(Q28546877)

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Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers

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scholarly article

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Europe PubMed Central

21 June 2017

Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers (English)

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Europe PubMed Central

21 June 2017

high-throughput screening

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Alzheimer's disease

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based on heuristic

inferred from title

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based on heuristic

inferred from title

6

object named as

Michael T Marty

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Europe PubMed Central

21 June 2017

Benjamin D Kuhns

object named as

Benjamin D Kuhns

5

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William L. Klein

10

object named as

William L Klein

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Europe PubMed Central

21 June 2017

author name string

Kyle C Wilcox

1

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Europe PubMed Central

21 June 2017

Matthew R Marunde

2

1 reference

Europe PubMed Central

21 June 2017

Aditi Das

3

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Europe PubMed Central

21 June 2017

Pauline T Velasco

4

1 reference

Europe PubMed Central

21 June 2017

Haoming Jiang

7

1 reference

Europe PubMed Central

21 June 2017

Chi-Hao Luan

8

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Europe PubMed Central

21 June 2017

Stephen G Sligar

9

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Europe PubMed Central

21 June 2017

language of work or name

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publication date

30 April 2015

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Europe PubMed Central

21 June 2017

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Europe PubMed Central

21 June 2017

10

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Europe PubMed Central

21 June 2017

4

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Europe PubMed Central

21 June 2017

e0125263

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Europe PubMed Central

21 June 2017

copyright license

Creative Commons Attribution 4.0 International

30 April 2015

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4415972/fullTextXML

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Cell Profiler

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein

1 reference

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Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

1 reference

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Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

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Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

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A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

1 reference

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1 reference

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1 reference

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1 reference

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29 September 2017

Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model

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29 September 2017

Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease

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1 reference

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P53 mdm2 inhibitors

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Modes of Aβ toxicity in Alzheimer's disease

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Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding

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Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity

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Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

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21 January 2018

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Monoclonal antibodies that target pathological assemblies of Abeta.

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21 January 2018

Self-assembly of Abeta(1-42) into globular neurotoxins.

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

10.1371/JOURNAL.PONE.0125263

1 reference

Europe PubMed Central

21 June 2017

2015PLoSO..1025263W

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1 reference

Europe PubMed Central

21 June 2017

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