(Q28564949)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Egr-1 transactivates Bim gene expression to promote neuronal apoptosis (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

Bo Xie

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Chong Wang

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Bin Song

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Chi Ma

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Gerald Thiel

6

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Mingtao Li

7

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

language of work or name

English

0 references

publication date

1 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

published in

Journal of Neuroscience

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

volume

31

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

issue

13

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

page(s)

5032-5044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

B-MYB transactivates its own promoter through SP1-binding sites

27 January 2020

cites work

1 reference

12 December 2020

Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription

1 reference

12 December 2020

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

12 December 2020

An enhanced expression of the immediate early gene, Egr-1, is associated with neuronal apoptosis in culture

1 reference

12 December 2020

Cellular survival: a play in three Akts

1 reference

12 December 2020

Inhibitory interaction of c-Myb and GATA-1 via transcriptional co-activator CBP

1 reference

12 December 2020

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

12 December 2020

Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta.

1 reference

12 December 2020

Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim

1 reference

12 December 2020

Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons

1 reference

12 December 2020

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

12 December 2020

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

12 December 2020

A dominant negative inhibitor of the Egr family of transcription regulatory factors suppresses cerebellar granule cell apoptosis by blocking c-Jun activation.

1 reference

12 December 2020

BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons

1 reference

12 December 2020

Myocyte enhancer factor 2A and 2D undergo phosphorylation and caspase-mediated degradation during apoptosis of rat cerebellar granule neurons.

1 reference

12 December 2020

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression

1 reference

12 December 2020

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

1 reference

12 December 2020

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

12 December 2020

Regulation of life and death by the zinc finger transcription factor Egr-1.

1 reference

12 December 2020

Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons.

1 reference

12 December 2020

The many forks in FOXO's road

1 reference

12 December 2020

Amyloid Peptide-Induced Cytokine and Chemokine Expression in THP-1 Monocytes Is Blocked by Small Inhibitory RNA Duplexes for Early Growth Response-1 Messenger RNA

1 reference

12 December 2020

Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons

1 reference

12 December 2020

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

1 reference

12 December 2020

Cerebellar granule cells as a model to study mechanisms of neuronal apoptosis or survival in vivo and in vitro

1 reference

12 December 2020

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

1 reference

12 December 2020

Specific interaction of Egr1 and c/EBPbeta leads to the transcriptional activation of the human low density lipoprotein receptor gene

1 reference

12 December 2020

Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

1 reference

12 December 2020

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

1 reference

12 December 2020

Indirubin-3'-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons

1 reference

12 December 2020

The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia

1 reference

12 December 2020

Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis.

1 reference

12 December 2020

Specificity of transcriptional regulation by the zinc finger transcription factors Sp1, Sp3, and Egr-1.

1 reference

12 December 2020

Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease

1 reference

12 December 2020

Temperature-dependent modification and activation of B-MYB: implications for cell survival.

1 reference

12 December 2020

Activity deprivation-dependent induction of the proapoptotic BH3-only protein Bim is independent of JNK/c-Jun activation during apoptosis in cerebellar granule neurons

1 reference

12 December 2020

Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway

1 reference

12 December 2020

BH3-only proteins: key regulators of neuronal apoptosis

1 reference

12 December 2020

BimEL up-regulation potentiates AIF translocation and cell death in response to MPTP.

1 reference

12 December 2020

Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors

1 reference

12 December 2020

Evidence for increased complexity in the regulation of Bim expression in sympathetic neurons: involvement of novel transcriptional and translational mechanisms

1 reference

12 December 2020

Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.

1 reference

12 December 2020

Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function

1 reference

12 December 2020

N-methyl-D-aspartate blocks activation of JNK and mitochondrial apoptotic pathway induced by potassium deprivation in cerebellar granule cells.

1 reference

12 December 2020

Neuroprotection by histone deacetylase-related protein

1 reference

12 December 2020

The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives

1 reference

12 December 2020

Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

1 reference

12 December 2020

Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death.

1 reference

12 December 2020

dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons

1 reference

12 December 2020

Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

1 reference

12 December 2020

Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis.

1 reference

12 December 2020

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

1 reference

12 December 2020

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

12 December 2020

The Wnt pool of glycogen synthase kinase 3beta is critical for trophic-deprivation-induced neuronal death

1 reference

12 December 2020

Transcription factor early growth response-1 induction mediates inflammatory gene expression and brain damage following transient focal ischemia

1 reference

12 December 2020

Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons

1 reference

12 December 2020

Multisite phosphorylation regulates Bim stability and apoptotic activity

1 reference

12 December 2020

Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis

1 reference

12 December 2020

The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons

1 reference

12 December 2020

Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons.

1 reference

12 December 2020

Mithramycin protects against dopaminergic neurotoxicity in the mouse brain after administration of methamphetamine

1 reference

12 December 2020

Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma

1 reference

12 December 2020

Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation

1 reference

12 December 2020

Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival

1 reference

12 December 2020

Mithramycin blocks protein binding and function of the SV40 early promoter

1 reference

12 December 2020

Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6.

1 reference

12 December 2020

Regulation of synapsin I gene expression by the zinc finger transcription factor zif268/egr-1

1 reference

12 December 2020

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

12 December 2020

Role of zinc-finger proteins Sp1 and zif268/egr-1 in transcriptional regulation of the human synaptobrevin II gene

1 reference

12 December 2020

Effect of DNA-binding drugs on early growth response factor-1 and TATA box-binding protein complex formation with the herpes simplex virus latency promoter

1 reference

12 December 2020

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells

1 reference

12 December 2020

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

12 December 2020

Mitochondrial toxins in models of neurodegenerative diseases. II: Elevated zif268 transcription and independent temporal regulation of striatal D1 and D2 receptor mRNAs and D1 and D2 receptor-binding sites in C57BL/6 mice during MPTP treatment

1 reference

12 December 2020

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

12 December 2020

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

12 December 2020

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

12 December 2020

10.1523/JNEUROSCI.5504-10.2011

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451041%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

2 references

31 January 2017