(Q28571864)

2

1 reference

31 January 2017

Tatiana V. Bykova

3

1 reference

31 January 2017

Svetlana G. Zubova

4

1 reference

31 January 2017

Valery A. Pospelov

Extension of life-span by introduction of telomerase into normal human cells

5

1 reference

31 January 2017

15 June 2012

1 reference

31 January 2017

1 reference

31 January 2017

11

1 reference

31 January 2017

12

1 reference

31 January 2017

2402–2407

1 reference

31 January 2017

1 reference

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 April 2017

1 reference

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 April 2017

1 reference

Upstream and downstream of mTOR

21 April 2017

1 reference

TOR signaling in growth and metabolism

21 April 2017

1 reference

Pseudo-DNA damage response in senescent cells

21 April 2017

1 reference

Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin

21 April 2017

1 reference

Extension of chronological life span in yeast by decreased TOR pathway signaling

21 April 2017

1 reference

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

21 April 2017

1 reference

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

21 April 2017

1 reference

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

21 April 2017

1 reference

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

21 April 2017

1 reference

Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression

21 April 2017

1 reference

Increased life span due to calorie restriction in respiratory-deficient yeast

21 April 2017

1 reference

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

21 April 2017

1 reference

Regulation of mTOR and cell growth in response to energy stress by REDD1.

21 April 2017

1 reference

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

21 April 2017

1 reference

Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

21 April 2017

1 reference

Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling

21 April 2017

1 reference

Molecular mechanisms of mTOR-mediated translational control

21 April 2017

1 reference

Genetics: influence of TOR kinase on lifespan in C. elegans

21 April 2017

1 reference

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

21 April 2017

1 reference

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

21 April 2017

1 reference

Hayflick, his limit, and cellular ageing.

21 April 2017

1 reference

Cellular senescence, cancer and aging: the telomere connection

21 January 2018

1 reference

A telomere-independent senescence mechanism is the sole barrier to Syrian hamster cell immortalization

21 January 2018

1 reference

Mechanisms of cellular senescence in human and mouse cells.

21 January 2018

1 reference

Putting the stress on senescence

21 January 2018

1 reference

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

21 January 2018

1 reference

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

21 January 2018

1 reference

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence

21 January 2018

1 reference

Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

21 January 2018

1 reference

PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR

21 January 2018

1 reference

Dysregulation of the TSC-mTOR pathway in human disease

21 January 2018

1 reference

mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer

21 January 2018

1 reference

mTOR signaling in disease

21 January 2018

1 reference

mTOR signaling in protein homeostasis: less is more?

21 January 2018

1 reference

Growth stimulation leads to cellular senescence when the cell cycle is blocked

21 January 2018

1 reference

Rapamycin decelerates cellular senescence

21 January 2018

1 reference

Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence

21 January 2018

1 reference

At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence.

21 January 2018

1 reference

Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential

21 January 2018

1 reference

p21(Waf1) is required for cellular senescence but not for cell cycle arrest induced by the HDAC inhibitor sodium butyrate

21 January 2018

1 reference

Paradoxical suppression of cellular senescence by p53

21 January 2018

1 reference

DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence

21 January 2018

1 reference

Weak p53 permits senescence during cell cycle arrest

21 January 2018

1 reference

Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells

21 January 2018

1 reference

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

21 January 2018

1 reference

mTORC1 signaling governs hematopoietic stem cell quiescence

21 January 2018

1 reference

mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.

21 January 2018

1 reference

Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster.

21 January 2018

1 reference

Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

21 January 2018

1 reference

Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.

21 January 2018

1 reference

Autophagy is required for extension of yeast chronological life span by rapamycin

21 January 2018

1 reference

Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

21 January 2018

1 reference

Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling

21 January 2018

1 reference

Conserved role of medium acidification in chronological senescence of yeast and mammalian cells

21 January 2018

1 reference

A new chronological survival assay in mammalian cell culture

21 January 2018

1 reference

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

21 January 2018

1 reference

Replicative aging in yeast: the means to the end

21 January 2018

1 reference

The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae

21 January 2018

1 reference

Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling

21 January 2018

1 reference

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

21 January 2018

1 reference

Hypoxia-induced energy stress regulates mRNA translation and cell growth

21 January 2018

1 reference

mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.

21 January 2018

1 reference

Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia

21 January 2018

1 reference

Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.

21 January 2018

1 reference

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

21 January 2018

1 reference