(Q28590806)

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Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage

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scholarly article

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31 January 2017

Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage (English)

1 reference

31 January 2017

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

13

object named as

Mark P. Mattson

1 reference

31 January 2017

13

object named as

Mark P Mattson

1 reference

Europe PubMed Central

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16 May 2020

author name string

Aiwu Cheng

1

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Kazuo Shin-ya

2

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Ruiqian Wan

3

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Sung-chun Tang

4

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Takumi Miura

5

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Hongyang Tang

6

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Rina Khatri

7

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Marc Gleichman

8

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Xin Ouyang

9

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Dong Liu

10

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Hae-Rong Park

11

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

Jeffrey Y Chiang

12

1 reference

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16 May 2020

language of work or name

0 references

publication date

4 April 2007

1 reference

31 January 2017

Journal of Neuroscience

2 references

31 January 2017

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16 May 2020

27

2 references

31 January 2017

Europe PubMed Central

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16 May 2020

3722-3733

1 reference

Europe PubMed Central

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16 May 2020

14

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672411&resulttype=core&format=json

16 May 2020

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-apoptotic role of telomerase in pheochromocytoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian telomeres end in a large duplex loop

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress induces caspase-independent retinal apoptosis in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-induced neuronal death is bax-dependent but caspase-independent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of programmed cell death in the developing brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase-1 in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of a caspase-3 dependent cell death in NT4- and p75-deficient embryonic sensory neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomeres and their control

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurogenesis in the adult brain: death of a dogma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal life and death: an essential role for the p53 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of telomerase activity and TERT expression during brain development in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of apoptosis to responses in the comet assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Switching and signaling at the telomere

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senescence Induced by Altered Telomere State, Not Telomere Loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-independent photoreceptor apoptosis in vivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive telomere loss is an early event of DNA damage-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of a fetal multipotent neural stem cell (NEP cell).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of telomeric DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase activity in the subventricular zone of adult mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage foci at dysfunctional telomeres

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinguishing features of progenitor cells in the late embryonic and adult hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal death after trophic factor deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The generation of cellular diversity in the cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane properties of rat embryonic multipotent neural stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRF2 is in neuroglial cytoplasm and induces neurite-like processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurogenesis in the adult brain: new strategies for central nervous system diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle activation linked to neuronal cell death initiated by DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomeres and telomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of telomerase by telomeric proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gap junctional communication is required to maintain mouse cortical neural progenitor cells in a proliferative state.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H2AX: the histone guardian of the genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of quadruplex DNA structures in human telomeres by a fluorescent carbazole derivative

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divide and die: cell cycle events as triggers of nerve cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase inhibition by siRNA causes senescence and apoptosis in Barrett's adenocarcinoma cells: mechanism and therapeutic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNS stem cells express a new class of intermediate filament protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constructing the cerebral cortex: neurogenesis and fate determination

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) synthetase activation: an early indicator of neurotoxic DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere reduction and telomerase inactivation during neuronal cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology of the neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomeric localization of TRF2, a novel human telobox protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bax involvement in p53-mediated neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 prevents caspase-independent cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17409236

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0590-07.2007

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672411&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672411&resulttype=core&format=json

16 May 2020

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672411&resulttype=core&format=json

16 May 2020

ResearchGate publication ID

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