(Q30753875)

English

Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 June 2017

Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

apoptotic process

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1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

3

object named as

Colin Adrain

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Europe PubMed Central

PubMed publication ID

26 June 2017

Seamus J. Martin

object named as

Seamus J Martin

5

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6

object named as

Gerald M Cohen

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

author name string

Davina Twiddy

1

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

David G Brown

2

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Rebekah Jukes

4

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Marion MacFarlane

7

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Kelvin Cain

8

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Europe PubMed Central

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26 June 2017

language of work or name

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publication date

1 March 2004

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Europe PubMed Central

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26 June 2017

Journal of Biological Chemistry

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Europe PubMed Central

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26 June 2017

279

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Europe PubMed Central

PubMed publication ID

26 June 2017

19

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Europe PubMed Central

PubMed publication ID

26 June 2017

19665-19682

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Europe PubMed Central

PubMed publication ID

26 June 2017

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

The mitochondrial apoptosome: a killer unleashed by the cytochrome seas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

The Apaf-1 apoptosome: a large caspase-activating complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Physiological concentrations of K+ inhibit cytochrome c-dependent formation of the apoptosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Caspase-9 and APAF-1 form an active holoenzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Mechanism of XIAP-mediated inhibition of caspase-9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Structural basis for the inhibition of caspase-3 by XIAP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Structural basis of caspase-7 inhibition by XIAP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

IAP proteins: blocking the road to death's door

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Caspase-9 can be activated without proteolytic processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Real-time single cell analysis of Smac/DIABLO release during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Negative regulation of the Apaf-1 apoptosome by Hsp70

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Cytochrome c binding to Apaf-1: the effects of dATP and ionic strength

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311388200

21 January 2018

Identifiers

10.1074/JBC.M311388200

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

ResearchGate publication ID

0 references

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