(Q33381199)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Characterization, chemical optimization and anti-tumour activity of a tubulin poison identified by a p53-based phenotypic screen (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

Alexandra Martha Zoya Slawin

25 December 2019

11

object named as

Alexandra M Z Slawin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Oliver D Staples

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Jonathan J Hollick

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Johanna Campbell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Maureen Higgins

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Anna R McCarthy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Virginia Appleyard

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Karen E Murray

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Lee Baker

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Alastair Thompson

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Sebastien Ronseaux

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Nicholas J Westwood

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Sonia Lain

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

publication date

15 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

number of pages

11

1 reference

inferred from page(s)

published in

Cell Cycle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

3417-3427

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

25 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Docking and hydropathic scoring of polysubstituted pyrrole compounds with antitubulin activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

The p53 tumor suppressor participates in multiple cell cycle checkpoints

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Update on tubulin-binding agents.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Genetic and genomic approaches to identify and study the targets of bioactive small molecules.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

The role of human papillomavirus oncoproteins E6 and E7 in apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Cyclin A in cell cycle control and cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Immunochemical analysis of the p53 oncoprotein in matched primary and metastatic human tumours.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Histone Phosphorylation and Chromatin Structure during Mitosis in Chinese Hamster Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Prolonged mitosis versus tetraploid checkpoint: how p53 measures the duration of mitosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709220

The use of esters as prodrugs for oral delivery of beta-lactam antibiotics

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18971638

12 December 2020

inferred from PubMed ID database lookup

DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18971638

12 December 2020

inferred from PubMed ID database lookup

The assessment of proliferating cell nuclear antigen (PCNA) immunostaining in primary gastrointestinal lymphomas and its relationship to histological grade, S+G2+M phase fraction (flow cytometric analysis) and prognosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18971638

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4161/CC.7.21.6982

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971638%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference