(Q33581891)

28 July 2017

title

Pin1 promotes transforming growth factor-beta-induced migration and invasion (English)

1 reference

28 July 2017

Takafumi Uchida

7

0 references

author name string

Isao Matsuura

1

1 reference

28 July 2017

Keng-Nan Chiang

2

1 reference

28 July 2017

Chen-Yu Lai

3

1 reference

28 July 2017

Dongming He

4

1 reference

28 July 2017

Guannan Wang

5

1 reference

28 July 2017

Romila Ramkumar

6

1 reference

28 July 2017

Akihide Ryo

8

1 reference

28 July 2017

Kunping Lu

9

1 reference

28 July 2017

Fang Liu

10

1 reference

28 July 2017

language of work or name

English

0 references

publication date

17 November 2009

1 reference

Journal of Biological Chemistry

28 July 2017

published in

1 reference

28 July 2017

volume

285

1 reference

28 July 2017

issue

3

1 reference

28 July 2017

page(s)

1754-1764

1 reference

Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer

28 July 2017

cites work

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21 June 2018

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The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

21 June 2018

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Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

21 June 2018

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Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability

21 June 2018

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21 June 2018

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21 June 2018

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Prolyl isomerase, Pin1: new findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer's disease

21 June 2018

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21 June 2018

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21 June 2018

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N-cadherin as a therapeutic target in cancer

21 June 2018

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Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel

21 June 2018

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PIN1 expression contributes to hepatic carcinogenesis.

21 June 2018

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Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2.

21 June 2018

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N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1.

21 June 2018

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Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction

21 June 2018

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Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

21 June 2018

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Smad3 phosphorylation by cyclin-dependent kinases

21 June 2018

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Stable suppression of tumorigenicity by Pin1-targeted RNA interference in prostate cancer

21 June 2018

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Specificity and versatility in tgf-beta signaling through Smads

21 June 2018

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Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3.

21 June 2018

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Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

21 June 2018

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Inhibition of Smad antiproliferative function by CDK phosphorylation

21 June 2018

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Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo

21 June 2018

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N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling

21 June 2018

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TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions

21 June 2018

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New insights into TGF-beta-Smad signalling

21 June 2018

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Prevalent overexpression of prolyl isomerase Pin1 in human cancers

21 June 2018

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Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 June 2018

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PIN1 overexpression and beta-catenin gene mutations are distinct oncogenic events in human hepatocellular carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Receptor-regulated Smads in TGF-beta signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

The two faces of transforming growth factor beta in carcinogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Regulation of TGF-beta signaling and its roles in progression of tumors

21 June 2018

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase

21 June 2018

1 reference

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Signal transduction by the TGF-beta superfamily

21 June 2018

1 reference

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Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes

21 June 2018

1 reference

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TGF-beta signaling in tumor suppression and cancer progression

21 June 2018

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Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

21 June 2018

1 reference

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Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation

21 June 2018

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Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 June 2018

1 reference

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TGFbeta signaling in growth control, cancer, and heritable disorders

21 June 2018

1 reference

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Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

21 June 2018

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Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 June 2018

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Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

21 June 2018

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Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Regulation of Smad7 promoter by direct association with Smad3 and Smad4.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer

21 June 2018

1 reference

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Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

21 June 2018

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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

The biochemistry of cancer dissemination

21 June 2018

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Cell adhesion: the molecular basis of tissue architecture and morphogenesis

21 June 2018

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A human peptidyl-prolyl isomerase essential for regulation of mitosis

21 June 2018

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The role of cell adhesion molecules in cancer invasion and metastasis

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 June 2018

1 reference

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Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.063826

Cyclin-dependent kinases regulate the antiproliferative function of Smads

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.063826

Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.

21 January 2018

1 reference

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PIN1, the cell cycle and cancer.

21 January 2018

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Overexpression of Pin1 in non-small cell lung cancer (NSCLC) and its correlation with lymph node metastases.

21 January 2018

1 reference

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Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.063826

Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804333

Integration of Smad and MAPK pathways: a link and a linker revisited

31 October 2018

1 reference

12 December 2020

The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta

1 reference

12 December 2020

Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription

1 reference

12 December 2020

Interaction and functional cooperation of NF-kappa B with Smads. Transcriptional regulation of the junB promoter

1 reference

12 December 2020

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.063826

1 reference

28 July 2017

1 reference

28 July 2017

1 reference