(Q33732180)

29 July 2017

title

Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice (English)

1 reference

29 July 2017

1 reference

5

Wilfried Nietfeld

0 references

Denise Harhausen

1

Denise Harhausen

0 references

Ulrich Dirnagl

6

Ulrich Dirnagl

0 references

George Trendelenburg

7

George Trendelenburg

0 references

Uldus Khojasteh

2

Uldus Khojasteh

0 references

author name string

Denise Harhausen

1

1 reference

29 July 2017

Uldus Khojasteh

2

1 reference

29 July 2017

Philip F Stahel

3

1 reference

29 July 2017

B Paul Morgan

4

1 reference

29 July 2017

Wilfried Nietfeld

5

1 reference

29 July 2017

George Trendelenburg

7

1 reference

29 July 2017

publication date

4 March 2010

1 reference

Journal of Neuroinflammation

29 July 2017

published in

1 reference

29 July 2017

volume

7

1 reference

29 July 2017

page(s)

15

1 reference

The complement cascade as a therapeutic target in intracerebral hemorrhage

29 July 2017

cites work

1 reference

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Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice.

21 June 2018

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Complement regulator CD59 protects against atherosclerosis by restricting the formation of complement membrane attack complex.

21 June 2018

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Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice.

21 June 2018

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Neuroprotection in stroke by complement inhibition and immunoglobulin therapy

21 June 2018

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21 June 2018

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21 June 2018

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CD59 efficiently protects human NT2-N neurons against complement-mediated damage

21 June 2018

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Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice

21 June 2018

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ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury

21 June 2018

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Complement mediators in ischemia-reperfusion injury

21 June 2018

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Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation

21 June 2018

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Pathophysiology and therapy of experimental stroke

21 June 2018

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The role of inflammation in CNS injury and disease

21 June 2018

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Ischemic neuroprotection with selective kappa-opioid receptor agonist is gender specific

21 June 2018

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Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury.

21 June 2018

1 reference

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Steady-state serum concentrations of progesterone following continuous intravenous infusion in patients with acute moderate to severe traumatic brain injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

CD59a deficiency exacerbates ischemia-reperfusion injury in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Critical protection from renal ischemia reperfusion injury by CD55 and CD59.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Oestrogen as a neuroprotective hormone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Pathobiology of ischaemic stroke: an integrated view

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Blocking of classical complement pathway inhibits endothelial adhesion molecule expression and preserves ischemic myocardium from reperfusion injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

CD59: its role in complement regulation and potential for therapeutic use.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Progesterone protects against lipid peroxidation following traumatic brain injury in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Sublytic concentrations of the membrane attack complex of complement induce endothelial interleukin-8 and monocyte chemoattractant protein-1 through nuclear factor-kappa B activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

The membrane attack complex of complement induces interleukin-8 and monocyte chemoattractant protein-1 secretion from human umbilical vein endothelial cells

21 June 2018

1 reference

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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination

21 June 2018

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Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects

21 June 2018

1 reference

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The complement cascade: new avenues in stroke therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

In situ deposition of complement in human acute brain ischaemia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Deficiency of the complement regulator CD59a exacerbates Wallerian degeneration.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Strong complement activation after acute ischemic stroke is associated with unfavorable outcomes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Complement-dependent P-selectin expression and injury following ischemic stroke

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

The administration of cobra venom factor reduces post-ischemic cerebral injury in adult and neonatal rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

C1-inhibitor protects against brain ischemia-reperfusion injury via inhibition of cell recruitment and inflammation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

CD59a is the primary regulator of membrane attack complex assembly in the mouse.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Selective neuronal vulnerability following mild focal brain ischemia in the mouse.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Modulation of leukocyte recruitment and IL-8 expression by the membrane attack complex of complement (C5b-9) in a rabbit model of antigen-induced arthritis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

The administration of complement component C9 augments post-ischemic cerebral infarction volume in neonatal rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

In stroke, complement will get you nowhere

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Progesterone facilitates the acquisition of avoidance learning and protects against subcortical neuronal death following prefrontal cortex ablation in the rat.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Estrogen increases cGMP in selected brain regions and in cerebral microvessels

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Progesterone rapidly decreases brain edema: treatment delayed up to 24 hours is still effective.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839971

Progesterone is neuroprotective after acute experimental spinal cord trauma in rats

30 October 2018

1 reference

12 December 2020

Upregulating CD59: a new strategy for protection of neurons from complement-mediated degeneration

1 reference

12 December 2020

Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria

1 reference

12 December 2020

Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers

1 reference

12 December 2020

The differing roles of the classical and mannose-binding lectin complement pathways in the events following skeletal muscle ischemia-reperfusion

1 reference

12 December 2020

Expression of complement regulators and receptors on human NT2-N neurons--effect of hypoxia and reoxygenation

1 reference

12 December 2020

Identifiers

DOI

10.1186/1742-2094-7-15

1 reference

Dimensions Publication ID

29 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1742-2094-7-15

9 September 2019

1 reference

29 July 2017

1 reference