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Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents.

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28 January 2020

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Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents (English)

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Europe PubMed Central

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28 January 2020

Boris Krasnikov

2

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28 January 2020

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Arthur J L Cooper

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28 January 2020

Zoya V Niatsetskaya

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28 January 2020

John T Pinto

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28 January 2020

Patrick S Callery

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28 January 2020

Maria T Villar

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28 January 2020

Antonio Artigues

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28 January 2020

Sam A Bruschi

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28 January 2020

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22 March 2010

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28 January 2020

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28 January 2020

41

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28 January 2020

1

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28 January 2020

7-27

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28 January 2020

Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds

1 reference

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Studies of a novel cysteine sulfoxide lyase from Petiveria alliacea: the first heteromeric alliinase

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Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells

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Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells

1 reference

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Biological properties of garlic and garlic-derived organosulfur compounds

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Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells

1 reference

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Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity

1 reference

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Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1.

1 reference

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The sequential action of a dipeptidase and a beta-lyase is required for the release of the human body odorant 3-methyl-3-sulfanylhexan-1-ol from a secreted Cys-Gly-(S) conjugate by Corynebacteria

1 reference

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5 July 2018

Metabolism of the cysteine S-conjugate of busulfan involves a beta-lyase reaction

1 reference

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Cancer chemoprevention by garlic and its organosulfur compounds-panacea or promise?

1 reference

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5 July 2018

Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase

1 reference

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5 July 2018

Cisplatin nephrotoxicity: molecular mechanisms.

1 reference

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5 July 2018

Selenium in chemistry and biochemistry in comparison to sulfur

1 reference

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5 July 2018

Chemical toxicology of reactive intermediates formed by the glutathione-dependent bioactivation of halogen-containing compounds

1 reference

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5 July 2018

Identification of the precursor of (S)-3-methyl-3-sulfanylhexan-1-ol, the sulfury malodour of human axilla sweat

1 reference

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Trichloroethylene cancer epidemiology: a consideration of select issues

1 reference

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5 July 2018

Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells

1 reference

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5 July 2018

Cytosolic heat shock proteins and heme oxygenase-1 are preferentially induced in response to specific and localized intramitochondrial damage by tetrafluoroethylcysteine

1 reference

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5 July 2018

Identification of Hsc70 binding sites in mitochondrial aspartate aminotransferase

1 reference

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5 July 2018

Redox-sensitive proteins are potential targets of garlic-derived mercaptocysteine derivatives.

1 reference

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5 July 2018

Cysteine S-conjugate beta-lyases

1 reference

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5 July 2018

Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60.

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5 July 2018

BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death.

1 reference

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5 July 2018

Glutathione-dependent bioactivation of haloalkanes and haloalkenes

1 reference

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5 July 2018

Crystal structure of human kynurenine aminotransferase I

1 reference

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5 July 2018

DNA intrastrand cross-link at the 5'-GA-3' sequence formed by busulfan and its role in the cytotoxic effect

1 reference

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5 July 2018

Biosynthesis of toxic glutathione conjugates from halogenated alkenes

1 reference

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5 July 2018

Role of CysteineS-Conjugate β-Lyase in the Metabolism of Cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898922

5 July 2018

New concepts in selenium chemoprevention

1 reference

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5 July 2018

Overexpression of glutathione S-transferase A1-1 in ECV 304 cells protects against busulfan mediated G2-arrest and induces tissue factor expression

1 reference

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5 July 2018

Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism

1 reference

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5 July 2018

Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions

1 reference

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5 July 2018

Chemistry and biological activity of novel selenium-containing compounds

1 reference

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5 July 2018

Antiproliferative effects of garlic-derived and other allium related compounds

1 reference

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5 July 2018

Cysteine conjugate of methazolamide is metabolized by beta-lyase

1 reference

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5 July 2018

Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate beta-lyase/glutamine transaminase K

1 reference

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5 July 2018

In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention

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5 July 2018

Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method

1 reference

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Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death

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Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study

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5 July 2018

Intranephron distribution of cysteine S-conjugate beta-lyase activity and its implication for hexachloro-1,3-butadiene-induced nephrotoxicity in rats

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5 July 2018

Cloning and expression of a rat kidney cytosolic glutamine transaminase K that has strong sequence homology to kynurenine pyruvate aminotransferase

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5 July 2018

Busulfan conjugation by glutathione S-transferases alpha, mu, and pi.

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5 July 2018

Isolation and expression of a cDNA coding for rat kidney cytosolic cysteine conjugate beta-lyase

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5 July 2018

Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process

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5 July 2018

Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway

1 reference

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5 July 2018

Molecular cloning of rat kynurenine aminotransferase: identity with glutamine transaminase K.

1 reference

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5 July 2018

Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity

1 reference

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Isolation from rat kidney of a cytosolic high molecular weight cysteine-S-conjugate beta-lyase with activity toward leukotriene E4.

1 reference

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Chemistry of the inactivation of cytosolic aspartate aminotransferase by serine O-sulfate

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Cysteine conjugate beta-lyase in the gastrointestinal bacterium Fusobacterium necrophorum

1 reference

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The metabolism of acetamidothiazoles in the rat. 2-acetamido-4-chloromethylthiazole

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5 July 2018

A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.

1 reference

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5 July 2018

Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites

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5 July 2018

Metabolism of leukotriene E4 to 5-hydroxy-6-mercapto7,9-trans-11,14-cis-eicosatetraenoic acid by microfloral cysteine-conjugate beta-lyase and rat cecum contents

1 reference

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5 July 2018

Complexes of sequential metabolic enzymes

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5 July 2018

Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria

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Covalent and noncovalent interactions in acute lethal cell injury caused by chemicals

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5 July 2018

Bioactivation of xenobiotics by formation of toxic glutathione conjugates

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In vivo metabolites of S-(2-benzothiazolyl)-L-cysteine as markers of in vivo cysteine conjugate beta-lyase and thiol glucuronosyl transferase activities

1 reference

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5 July 2018

Nephrotoxicity of halogenated alkenyl cysteine-S-conjugates

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5 July 2018

Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts

1 reference

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5 July 2018

Glutamine transaminase K and cysteine S-conjugate β-lyase activity stains

1 reference

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5 July 2018

Cysteine conjugate beta-lyase in rat liver. A novel enzyme catalyzing formation of thiol-containing metabolites of drugs

1 reference

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5 July 2018

The metabolism of bromazepam in the rat—identification of mercapturic acid and its conversion in vitro to methylthio-bromazepam

1 reference

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Stereochemistry of reactions of the inhibitor/substrates L- and D-beta-chloroalanine with beta-mercaptoethanol catalysed by L-aspartate aminotransferase and D-amino acid aminotransferase respectively

1 reference

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21 January 2018

Binding to chaperones allows import of a purified mitochondrial precursor into mitochondria

1 reference

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21 January 2018

Aminotransferase, L-amino acid oxidase and beta-lyase reactions involving L-cysteine S-conjugates found in allium extracts. Relevance to biological activity?

1 reference

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21 January 2018

Co-purification of mitochondrial HSP70 and mature protein disulfide isomerase with a functional rat kidney high-M(r) cysteine S-conjugate beta-lyase

1 reference

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21 January 2018

Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation

1 reference

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21 January 2018

Variable expression of glutathione S-transferase isoenzymes in the fungus, Mucor circinelloides.

1 reference

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21 January 2018

A fast SEQUEST cross correlation algorithm

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21 January 2018

Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

1 reference

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21 January 2018

Metabolism of mercapturic acid-pathway metabolites of 2-chloro-N-isopropylacetanilide (propachlor) by gastrointestinal bacteria

1 reference

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21 January 2018

Identification of odoriferous sulfanylalkanols in human axilla secretions and their formation through cleavage of cysteine precursors by a C-S lyase isolated from axilla bacteria.

1 reference

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21 January 2018

Methylation and demethylation of intermediates selenide and methylselenol in the metabolism of selenium

1 reference

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21 January 2018

Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human.

1 reference

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21 January 2018

Comparative study on the bioactivation mechanisms and cytotoxicity of Te-phenyl-L-tellurocysteine, Se-phenyl-L-selenocysteine, and S-phenyl-L-cysteine

1 reference

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21 January 2018

Bioactivation of selenocysteine derivatives by beta-lyases present in common gastrointestinal bacterial species

1 reference

https://api.crossref.org/works/10.1007%2FS00726-010-0552-0

21 January 2018

Comparison of volatile constituents of Persicaria odorata(Lour.) Soják (Polygonum odoratum Lour.) and Persicaria hydropiper L. Spach (Polygonum hydropiper L.).

1 reference

https://api.crossref.org/works/10.1007%2FS00726-010-0552-0

21 January 2018

Olfactory perception of cysteine-S-conjugates from fruits and vegetables

1 reference

https://api.crossref.org/works/10.1007%2FS00726-010-0552-0

21 January 2018

Selenocysteine beta-lyase and methylselenol demethylase in the metabolism of Se-methylated selenocompounds into selenide.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-010-0552-0

21 January 2018

Stereochemical course of the generation of 3-mercaptohexanal and 3-mercaptohexanol by beta-lyase-catalyzed cleavage of cysteine conjugates

1 reference

https://api.crossref.org/works/10.1007%2FS00726-010-0552-0

21 January 2018

Selenium metabolism in rats with long-term ingestion of Se-methylselenocysteine using enriched stable isotopes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898922

29 October 2018

Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898922

29 October 2018

Evaluation of the kinetics of beta-elimination reactions of selenocysteine Se-conjugates in human renal cytosol: possible implications for the use as kidney selective prodrugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898922

29 October 2018

Glutamine transaminase K is not a major cysteine S-conjugate beta-lyase of rat kidney mitochondria: evidence that a high-molecular weight enzyme fulfills this role.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898922

29 October 2018

Cysteine conjugate beta-lyase activity in three species of parasitic helminth

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acylase-catalyzed deacetylation of haloalkene-derived mercapturates

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of mammary cancer with Se-allylselenocysteine and other selenoamino acids in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterisation of a novel cysteine conjugate beta-lyase from the tapeworm Moniezia expansa

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro effects of Se-allylselenocysteine and Se-propylselenocysteine on cell growth, DNA integrity, and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic pathways of beta elimination of chemopreventive selenocysteine Se conjugates

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CLEAVAGE OF S-(1,2-DICHLOROVINYL)-L-CYSTEINE BY ESCHERICHIA COLI B

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

THE BIOTRANSFORMATION OF A SULFONAMIDE TO A MERCAPTAN AND TO MERCAPTURIC ACID AND GLUCURONIDE CONJUGATES

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo detection and characterization of protein adducts resulting from bioactivation of haloethene cysteine S-conjugates by 19F NMR: chlorotrifluoroethene and tetrafluoroethene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of 76Se-methylselenocysteine compared with that of 77Se-selenomethionine and 82Se-selenite

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinatorial synthesis by nature: volatile organic sulfur-containing constituents of Ruta chalepensis L

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Volatile organic sulfur-containing constituents in Poncirus trifoliata (L.) Raf. (Rutaceae)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine-conjugate β-Lyase from Mucor javanicus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporation of radiolabelled amino acids into the sulphur-containing metabolites of paracetamol by the hamster

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine conjugate beta-lyase in the gastrointestinal bacterium Eubacterium limosum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of a rat liver enzyme with both cysteine conjugate beta-lyase and kynureninase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formate-induced labeling of the active site of aspartate aminotransferase by beta-chloro-L-alanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Protective Effect of Thiosulfate upon the Inactivation of Aspartate. Aminotransferase by Aminoacrylic-Acid-Producing Substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of S-(1,2-dichlorovinyl)-l-cysteine by an enzyme of bovine origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of C-S lyase from Fusobacterium varium. A C-S cleavage enzyme of cysteine conjugates and some S-containing amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine conjugate beta-lyase and the thiomethyl shunt

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of 2,4',5-trichlorobiphenyl by the mercapturic acid pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A C-S bond cleavage enzyme of cysteine conjugates in intestinal microorganisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting 6-thioguanine to the kidney with S-(guanin-6-yl)-L-cysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homologous proteins with different affinities for groEL. The refolding of the aspartate aminotransferase isozymes at varying temperatures

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of 6-mercaptopurine to the kidneys. Metabolism and kidney-selectivity of S-(6-purinyl)-L-cysteine analogs in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation, characterization, and immunoreactivity of lysine thioamide adducts from fluorinated nephrotoxic cysteine conjugates in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of beta-elimination reactions in rat renal cytosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Busulfan-glutathione conjugation catalyzed by human liver cytosolic glutathione S-transferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative cytotoxicity of 14 novel selenocysteine se-conjugates in rat renal proximal tubular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20306345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00726-010-0552-0

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20306345%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20306345%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20306345%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

ResearchGate publication ID

0 references

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