(Q34284968)

1 August 2017

title

Splice variants of SmgGDS control small GTPase prenylation and membrane localization (English)

1 reference

1 August 2017

Tracy J Berg

1

1 reference

1 August 2017

Adam J Gastonguay

2

1 reference

1 August 2017

Ellen L Lorimer

3

1 reference

1 August 2017

John R Kuhnmuench

4

1 reference

1 August 2017

Rongshan Li

5

1 reference

1 August 2017

Alan P Fields

6

1 reference

1 August 2017

Carol L Williams

7

1 reference

1 August 2017

language of work or name

English

0 references

publication date

13 August 2010

1 reference

Journal of Biological Chemistry

1 August 2017

published in

1 reference

1 August 2017

volume

285

1 reference

1 August 2017

issue

46

1 reference

1 August 2017

page(s)

35255-35266

1 reference

describes a project that uses

1 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2975149/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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6 July 2018

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TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

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Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators

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6 July 2018

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6 July 2018

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The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences

6 July 2018

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Ras proteins: different signals from different locations

6 July 2018

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6 July 2018

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6 July 2018

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Involvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signaling

6 July 2018

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Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Prenylation and palmitoylation analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism

6 July 2018

1 reference

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A repeating amino acid motif shared by proteins with diverse cellular roles

6 July 2018

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6 July 2018

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p21ras is modified by a farnesyl isoprenoid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

All ras proteins are polyisoprenylated but only some are palmitoylated

6 July 2018

1 reference

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6 July 2018

1 reference

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

In vitro identification of a soluble protein:geranylgeranyl transferase from rat tissues.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

The posttranslationally modified C-terminal structure of bovine aortic smooth muscle rhoA p21.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975149

Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.129916

Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.129916

The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.129916

Unique in vivo associations with SmgGDS and RhoGDI and different guanine nucleotide exchange activities exhibited by RhoA, dominant negative RhoA(Asn-19), and activated RhoA(Val-14).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.129916

betaPak-interacting exchange factor-mediated Rac1 activation requires smgGDS guanine nucleotide exchange factor in basic fibroblast growth factor-induced neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.129916

Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.129916

Farnesyltransferase inhibitors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20709748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Post-prenylation-processing enzymes as new targets in oncogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20709748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.129916

1 reference

1 August 2017

1 reference

1 August 2017

1 reference