(Q34412599)

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Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease

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scholarly article

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Europe PubMed Central

2 August 2017

Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease (English)

1 reference

Europe PubMed Central

2 August 2017

cystic fibrosis

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pulmonary emphysema

1 reference

based on heuristic

inferred from title

2

1 reference

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12 June 2020

Simon Y Graeber

5

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12 June 2020

Carsten Schultz

10

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12 June 2020

Alexander Dalpke

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object named as

Alexander H Dalpke

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12 June 2020

author name string

Stefanie Gehrig

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12 June 2020

Michael Weitnauer

3

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12 June 2020

Claudius J Wagner

4

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12 June 2020

Jolanthe Schatterny

6

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12 June 2020

Stephanie Hirtz

7

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12 June 2020

Abderrazzaq Belaaouaj

8

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12 June 2020

Marcus A Mall

11

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12 June 2020

language of work or name

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publication date

1 May 2014

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2 August 2017

American Journal of Respiratory and Critical Care Medicine

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12 June 2020

189

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12 June 2020

9

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12 June 2020

1082-1092

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12 June 2020

Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Risk Factors for Bronchiectasis in Children with Cystic Fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Early lung disease in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Sputum biomarkers of inflammation and lung function decline in children with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Proteases and cystic fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Neutrophil serine proteases: specific regulators of inflammation

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Leukocyte elastase: physiological functions and role in acute lung injury

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Airway mucus function and dysfunction

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Elastolytic proteases: inflammation resolution and dysregulation in chronic infective lung disease.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Role of the amiloride-sensitive epithelial Na+ channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Neutrophil Elastase Mediates Innate Host Protection against Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Airway surface dehydration in cystic fibrosis: pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Development of chronic bronchitis and emphysema in beta-epithelial Na+ channel-overexpressing mice.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

FRET-based and other fluorescent proteinase probes.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Allergic airway inflammation induces a pro-secretory epithelial ion transport phenotype in mice

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Novel method to process cystic fibrosis sputum for determination of oxidative state

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Increased DNA levels in bronchoalveolar lavage fluid obtained from infants with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Neutrophil elastase induces mucus cell metaplasia in mouse lung.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Association between pulmonary function and sputum biomarkers in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Deficiency in Neutrophil Elastase Does Not Impair Neutrophil Recruitment to Inflamed Sites

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Subunit composition determines the single channel kinetics of the epithelial sodium channel

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Pharmacological therapy for cystic fibrosis: from bench to bedside

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

The innate immune system in cystic fibrosis lung disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Inhibition of airway proteases in cystic fibrosis lung disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Efficacy, safety and effect on biomarkers of AZD9668 in cystic fibrosis.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Neutrophil elastase inhibitors

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Proteases and emphysema

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Animal models for COPD.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Magnetic Resonance Imaging Detects Changes in Structure and Perfusion, and Response to Therapy in Early Cystic Fibrosis Lung Disease

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Competition between elastase and related proteases from human neutrophil for binding to alpha1-protease inhibitor.

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Detection of Anaerobic Bacteria in High Numbers in Sputum from Patients with Cystic Fibrosis

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Spatially Resolved Monitoring of Neutrophil Elastase Activity with Ratiometric Fluorescent Reporters

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201311-1932OC

21 January 2018

Identifiers

10.1164/RCCM.201311-1932OC

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24678594%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24678594%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

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