(Q34437920)

2 August 2017

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title

Pharmacokinetic considerations in the treatment of inflammatory bowel disease (English)

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inflammatory bowel diseases

2 August 2017

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Schwab M

1

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2 August 2017

Klotz U

series ordinal

2

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2 August 2017

language of work or name

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1 January 2001

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Clinical Pharmacokinetics

2 August 2017

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2 August 2017

40

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2 August 2017

10

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2 August 2017

723-751

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https://scigraph.springernature.com/pub.10.2165/00003088-200140100-00003

2 August 2017

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cites work

Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease

1 reference

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https://api.crossref.org/works/10.2165%2F00003088-200140100-00003

The pharmacokinetics of methotrexate and its 7-hydroxy metabolite in patients with rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.2165%2F00003088-200140100-00003

The impact of immunosuppressive drugs on the analysis of T cell activation

21 January 2018

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Drug-drug interactions with antirheumatic agents: review of selected clinically important interactions

21 January 2018

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12 December 2020

Biological effects of cyclosporin A: A new antilymphocytic agent

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12 December 2020

Clinical pharmacokinetics of slow release mesalazine

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12 December 2020

Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6-mercaptopurine and azathioprine

1 reference

12 December 2020

Methylprednisolone versus prednisolone pharmacokinetics in relation to dose in adults

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12 December 2020

Impairment of prednisolone disposition in patients with Graves' disease taking methimazole

1 reference

12 December 2020

An experiment to determine the active therapeutic moiety of sulphasalazine

1 reference

12 December 2020

Effect of dose size on the pharmacokinetics of intravenous hydrocortisone during endogenous hydrocortisone suppression

1 reference

12 December 2020

Identification of factors regulating thiopurine methyltransferase activity in a Norwegian population

1 reference

12 December 2020

Concentrations of 5-ASA and Ac-5-ASA in human ileocolonic biopsy homogenates after oral 5-ASA preparations

1 reference

12 December 2020

Effect of dose size on bioavailability of ciprofloxacin

1 reference

12 December 2020

Mesalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in chronic inflammatory bowel disease

1 reference

12 December 2020

Alterations in the mucosal immune system in ulcerative colitis and Crohn's disease.

1 reference

12 December 2020

Alterations in prednisolone disposition as a result of time of administration, gender and dose

1 reference

12 December 2020

Metronidazole elimination is preserved in the elderly

1 reference

12 December 2020

Low-Dose Cyclosporine for the Treatment of Crohn's Disease

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12 December 2020

Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

1 reference

12 December 2020

Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers

1 reference

12 December 2020

Review article: the clinical role of anti-TNFalpha antibody treatment in Crohn's disease

1 reference

12 December 2020

Clinical pharmacokinetics of cyclosporin

1 reference

12 December 2020

Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy

1 reference

12 December 2020

Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol

1 reference

12 December 2020

Azathioprine for maintaining remission of Crohn's disease

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12 December 2020

Efficacy of low-dose methotrexate in rheumatoid arthritis

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12 December 2020

Immunobiology and immunotherapeutic implications of syngeneic/autologous graft-versus-host disease.

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12 December 2020

Urinary excretion of 6 beta-hydroxycortisol as an in vivo marker for CYP3A induction: applications and recommendations

1 reference

12 December 2020

Dose dependent pharmacokinetics of prednisolone

1 reference

12 December 2020

Oral mesalazine for the treatment of Crohn's disease: clinical efficacy with respect to pharmacokinetic properties.

1 reference

12 December 2020

Enhanced prednisolone elimination: a possible cause for failure of glucocorticoid therapy in Graves' ophthalmopathy

1 reference

12 December 2020

Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with ulcerative colitis

1 reference

12 December 2020

Oroileal transit of slow release 5-aminosalicylic acid

1 reference

12 December 2020

Cytokines (immunoinflammatory hormones) and their natural regulation in inflammatory bowel disease (Crohn's disease and ulcerative colitis): a review

1 reference

12 December 2020

Newer 5-aminosalicylic acid based drugs in chronic inflammatory bowel disease

1 reference

12 December 2020

Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis

1 reference

12 December 2020

Dose dependent pharmacokinetics of prednisone and prednisolone in man

1 reference

12 December 2020

Grapefruit juice can increase the plasma concentrations of oral methylprednisolone

1 reference

12 December 2020

Drug interactions with grapefruit juice

1 reference

12 December 2020

Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers.

1 reference

12 December 2020

Topical and systemic availability of 5-aminosalicylate: comparisons of three controlled release preparations in man.

1 reference

12 December 2020

Medical therapy for ulcerative colitis

1 reference

12 December 2020

Studies on the mechanism of formation of 5-mercapto-1-methyl-4-nitroimidazole, a metabolite of the immunosuppressive drug azathioprine

1 reference

12 December 2020

Cyclosporine in severe ulcerative colitis refractory to steroid therapy

1 reference

12 December 2020

Gastrointestinal spread of oral prolonged-release mesalazine microgranules (Pentasa) dosed as either tablets or sachet

1 reference

12 December 2020

Medical therapy for inflammatory bowel disease

1 reference

12 December 2020

Disposition of pulse dose methylprednisolone in adult and paediatric patients with the nephrotic syndrome

1 reference

12 December 2020

1 reference

12 December 2020

Clinical pharmacokinetics of prednisone and prednisolone

1 reference

12 December 2020

Pharmacokinetics of 5-aminosalicylic acid in man following administration of intravenous bolus andper os slow-release formulation

1 reference

12 December 2020

Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid

1 reference

12 December 2020

Oral contraceptive effects on methylprednisolone pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

Intravenous cyclosporine in attacks of ulcerative colitis: short-term and long-term responses

1 reference

12 December 2020

Prolonged-release mesalazine: a review of its therapeutic potential in ulcerative colitis and Crohn's disease

1 reference

12 December 2020

Pharmacokinetics of metronidazole in patients with enteric disease compared to normal volunteers

1 reference

12 December 2020

Use of cytotoxic agents and cyclosporine in the treatment of autoimmune disease. Part 2: Inflammatory bowel disease, systemic vasculitis, and therapeutic toxicity.

1 reference

12 December 2020

Intestinal metabolism and transport of 5-aminosalicylate

1 reference

12 December 2020

Effect of route of administration and effusions on methotrexate pharmacokinetics.

1 reference

12 December 2020

Marked alterations in dose-dependent prednisolone kinetics in women taking oral contraceptives

1 reference

12 December 2020

Randomised controlled trial of azathioprine withdrawal in ulcerative colitis

1 reference

12 December 2020

Combination ciprofloxacin and metronidazole for active Crohn's disease

1 reference

12 December 2020

Reduced inter- and intraindividual variability in cyclosporine pharmacokinetics from a microemulsion formulation

1 reference

12 December 2020

Controlled trial of azathioprine in Crohn's disease

1 reference

12 December 2020

Azathioprine combined with prednisolone or monotherapy with prednisolone in active Crohn's disease

1 reference

12 December 2020

Steady-state pharmacokinetics of a new 4-gram 5-aminosalicylic acid retention enema in patients with ulcerative colitis in remission.

1 reference

12 December 2020

Pancytopenia associated with low dose methotrexate therapy. A regional survey

1 reference

12 December 2020

Aspirin is not associated with more toxicity than other nonsteroidal antiinflammatory drugs in patients with rheumatoid arthritis treated with methotrexate

1 reference

12 December 2020

Availability of mesalazine (5-aminosalicylic acid) from enemas and suppositories during steady-state conditions

1 reference

12 December 2020

Pharmacokinetics of Ciprofloxacin in the Elderly

1 reference

12 December 2020

Methotrexate for the Treatment of Crohn's Disease

1 reference

12 December 2020

Antibacterial therapy for Crohn's disease: a review emphasizing therapy directed against mycobacteria

1 reference

12 December 2020

Methotrexate in chronic active Crohn's disease: a double-blind, randomized, Israeli multicenter trial

1 reference

12 December 2020

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Pharmacokinetics of budesonide enema in patients with distal ulcerative colitis or proctitis.

1 reference

12 December 2020

Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus

1 reference

12 December 2020

Distribution of mesalazine enemas in active and quiescent ulcerative colitis

1 reference

12 December 2020

Effect of oral prophylactic broad spectrum nonabsorbable antibiotics on the gastrointestinal absorption of nutrients and methotrexate in small cell bronchogenic carcinoma patients

1 reference

12 December 2020

Long-term 6-mercaptopurine treatment in adolescents with Crohn's disease.

1 reference

12 December 2020

Pharmacokinetics of oral ciprofloxacin, 100 mg single dose, in volunteers and elderly patients

1 reference

12 December 2020

Methotrexate in chronic active ulcerative colitis: a double-blind, randomized, Israeli multicenter trial

1 reference

12 December 2020

Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis

1 reference

12 December 2020

Effects of ketoconazole on methylprednisolone pharmacokinetics and cortisol secretion

1 reference

12 December 2020

Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis

1 reference

12 December 2020

Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease

1 reference

12 December 2020

New therapeutic approaches to Crohn's disease

1 reference

12 December 2020

Medical therapy for induction and maintenance of remission in pouchitis: a systematic review

1 reference

12 December 2020

Ketoconazole effects on methylprednisolone disposition and their joint suppression of endogenous cortisol

1 reference

12 December 2020

Pharmacokinetics of oral methotrexate in children.

1 reference

12 December 2020

Bioavailability of low-dose vs high-dose 6-mercaptopurine

1 reference

12 December 2020

Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism

1 reference

12 December 2020

Clarithromycin clinical pharmacokinetics

1 reference

12 December 2020

Balsalazide and azathiprine or 6-mercaptopurine: evidence for a potentially serious drug interaction

1 reference

12 December 2020

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

1 reference

12 December 2020

A Controlled Trial of Azathioprine in the Management of Chronic Ulcerative Colitis

1 reference

12 December 2020

Azathioprine pharmacokinetics after intravenous, oral, delayed release oral and rectal foam administration

1 reference

12 December 2020

Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations

1 reference

12 December 2020

Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease

1 reference

12 December 2020

The therapeutic efficacy of 6-mercaptopurine in refractory ulcerative colitis.

1 reference

12 December 2020

Randomized, double-blind, placebo controlled trial of low-dose pulse methotrexate in psoriatic arthritis

1 reference

12 December 2020

Spread and distribution of 5-ASA colonic foam and 5-ASA enema in patients with ulcerative colitis

1 reference

12 December 2020

Isolation, characterization and in vitro activity of human cyclosporin A metabolites

1 reference

12 December 2020

Pharmacokinetics and protein binding of prednisolone after oral and intravenous administration

1 reference

12 December 2020

Intravenous cyclosporine for steroid-refractory attacks of Crohn's disease. Short- and long-term results.

1 reference

12 December 2020

Pharmacokinetic data for different 5-aminosalicylic acid and budesonide preparations

1 reference

12 December 2020

Pancytopenia from using trimethoprim and methotrexate

1 reference

12 December 2020

St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature.

1 reference

12 December 2020

Modified elimination of prednisolone in epileptic patients on carbamazepine monotherapy, and in women using low-dose oral contraceptives

1 reference

12 December 2020

Efficacy of intravenous cyclosporine for steroid refractory attacks of ulcerative colitis.

1 reference

12 December 2020

Oral delayed-release mesalazine: a review of its use in ulcerative colitis and Crohn's disease

1 reference

12 December 2020

Secretion imbalance between tumour necrosis factor and its inhibitor in inflammatory bowel disease

1 reference

12 December 2020

Inflammatory bowel disease

1 reference

12 December 2020

Comparative pharmacokinetics of methylprednisolone phosphate and hemisuccinate in high doses

1 reference

12 December 2020

Bioavailability of single and multiple doses of a new oral formulation of 5-ASA in patients with inflammatory bowel disease and healthy volunteers

1 reference

12 December 2020

Systemic and intestinal pharmacokinetics of methotrexate in patients with inflammatory bowel disease

1 reference

12 December 2020

Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide

1 reference

12 December 2020

Cyclosporin. A review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (Neoral).

1 reference

12 December 2020

Cyclosporine therapy for autoimmune disease.

1 reference

12 December 2020

Clinical outcome following treatment of refractory inflammatory and fistulizing Crohn's disease with intravenous cyclosporine

1 reference

12 December 2020

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

1 reference

12 December 2020

Metronidazole kinetics in patients with acute renal failure on dialysis: a cumulative study

1 reference

12 December 2020

Azathioprine: state of the art in inflammatory bowel disease

1 reference

12 December 2020

Plasma concentrations and effects of oral methylprednisolone are considerably increased by itraconazole

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of prednisolone after intravenous and oral administration

1 reference

12 December 2020

Review article: Drug development in inflammatory bowel disease: budesonide--a model of targeted therapy.

1 reference

12 December 2020

Disposition of 5-aminosalicylic acid from 5-aminosalicylic acid-delivering drugs during accelerated intestinal transit in healthy volunteers

1 reference

12 December 2020

Colonic N-acetylation of 5-aminosalicylic acid in inflammatory bowel disease

1 reference

12 December 2020

Final report on a placebo-controlled, double-blind, randomized, multicentre trial of cyclosporin treatment in active chronic Crohn's disease

1 reference

12 December 2020

Delivery and fate of oral mesalamine microgranules within the human small intestine

1 reference

12 December 2020

A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine

1 reference

12 December 2020

A review of immune modifier therapy for inflammatory bowel disease: azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate.

1 reference

12 December 2020

Methotrexate kinetics in rheumatoid arthritis: is there an interaction with nonsteroidal antiinflammatory drugs?

1 reference

12 December 2020

The pharmacokinetics of ciprofloxacin in patients with impaired renal function

1 reference

12 December 2020

Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine

1 reference

12 December 2020

Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction

1 reference

12 December 2020

Mercaptopurine metabolism and risk of relapse in childhood lymphoblastic leukaemia

1 reference

12 December 2020

Budesonide in the treatment of Crohn's disease: a meta-analysis

1 reference

12 December 2020

Methotrexate for the treatment of refractory Crohn's disease

1 reference

12 December 2020

The systemic load and efficient delivery of active 5-aminosalicylic acid in patients with ulcerative colitis on treatment with olsalazine or mesalazine

1 reference

12 December 2020

Prandial and diurnal effects on the absorption of orally administered enteric coated 5-aminosalicylic acid (5-ASA)

1 reference

12 December 2020

The clinical pharmacology of 6-mercaptopurine

1 reference

12 December 2020

Reduction of the inhibitory effect of ketoconazole on budesonide pharmacokinetics by separation of their time of administration.

1 reference

12 December 2020

Absorption of oral mesalazine-containing preparations and the influence of famotidine on the absorption

1 reference

12 December 2020

Mechanisms of action of cyclosporine.

1 reference

12 December 2020

Ciprofloxacin pharmacokinetics in patients with normal and impaired renal function

1 reference

12 December 2020

How to do without steroids in inflammatory bowel disease

1 reference

12 December 2020

Ulcerative colitis practice guidelines in adults. American College of Gastroenterology, Practice Parameters Committee.

1 reference

12 December 2020

Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers

1 reference

12 December 2020

Inflammatory bowel disease approaching the 3rd millennium: pathogenesis and therapeutic implications?

1 reference

12 December 2020

Clinical Pharmacokinetics of Methotrexate1

1 reference

12 December 2020

Distribution and concentrations of 5-aminosalicylic acid in rectosigmoid biopsy specimens after rectal administration.

1 reference

12 December 2020

Methotrexate in rheumatoid arthritis. An update

1 reference

12 December 2020

Methylprednisolone pharmacokinetics after intravenous and oral administration

1 reference

12 December 2020

Cyclosporin pharmacokinetics in the elderly

1 reference

12 December 2020

Diet and cyclosporin A--pharmacokinetic comparison between Neoral and Sandimmune gelatin capsules.

1 reference

12 December 2020

Metabolism and urinary excretion of 5-amino salicylic acid in healthy volunteers when given intravenously or released for absorption at different sites in the gastrointestinal tract

1 reference

12 December 2020

Evaluation of dose-related pharmacokinetics and pharmacodynamics of prednisolone in man

1 reference

12 December 2020

Pharmacology and pharmacokinetics of 5-aminosalicylic acid

1 reference

12 December 2020

Budesonide. A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease

1 reference

12 December 2020

Long-term treatment of ulcerative colitis with ciprofloxacin: a prospective, double-blind, placebo-controlled study

1 reference

12 December 2020

Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

1 reference

12 December 2020

Anastomotic configuration and mucosal 5-aminosalicyclic acid (5-ASA) concentrations in patients with Crohn's disease: a GISC study. Gruppo Italiano per lo Studio del Colon e del Retto

1 reference

12 December 2020

High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy

1 reference

12 December 2020

Negligible excretion of 5-aminosalicylic acid in breast milk

1 reference

12 December 2020

The pharmacokinetics and colonic tissue concentrations of cyclosporine after i.v., oral, and enema administration

1 reference

12 December 2020

Steady-state pharmacokinetics of enteric coated 5-amino-salicylic acid tablets in healthy volunteers and in patients with Crohn's disease or ulcerative colitis

1 reference

12 December 2020

Immunopharmacology of 5-aminosalicylic acid and of glucocorticoids in the therapy of inflammatory bowel disease.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of the nitroimidazole antimicrobials

1 reference

12 December 2020

Double blind, placebo controlled trial of metronidazole in Crohn's disease

1 reference

12 December 2020

6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity

1 reference

12 December 2020

Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study

1 reference

12 December 2020

Pharmacokinetic drug interactions with cyclosporin (Part I).

1 reference

12 December 2020

A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators

1 reference

12 December 2020

Pharmacokinetics of ciprofloxacin after intravenous and increasing oral doses

1 reference

12 December 2020

Mechanism of antimicrobial action of metronidazole

1 reference

12 December 2020

Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.

1 reference

12 December 2020

Pharmacokinetics and Rectal Bioavailability of Hydrocortisone Acetate

1 reference

12 December 2020

Dose loading with delayed-release mesalazine: a study of tissue drug concentrations and standard pharmacokinetic parameters

1 reference

12 December 2020

An intravenous loading dose of azathioprine decreases the time to response in patients with Crohn's disease

1 reference

12 December 2020

Review article: new developments in the use of 5-aminosalicylic acid in patients with inflammatory bowel disease

1 reference

12 December 2020

6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity

1 reference

12 December 2020

Dose-dependent prednisolone kinetics

1 reference

12 December 2020

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine

1 reference

12 December 2020

Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient

1 reference

12 December 2020

Pharmacokinetic drug interactions with cyclosporin (Part II).

1 reference

12 December 2020

Mycobacterium paratuberculosis cervical lymphadenitis, followed five years later by terminal ileitis similar to Crohn's disease

1 reference

12 December 2020

Pharmacology of cyclosporine (sandimmune). III. Immunochemistry and monitoring

1 reference

12 December 2020

Therapeutic Efficacy of Sulfasalazine and Its Metabolites in Patients with Ulcerative Colitis and Crohn's Disease

1 reference

12 December 2020

Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives

1 reference

12 December 2020

Update: clinically significant cytochrome P-450 drug interactions

1 reference

12 December 2020

The optimal use of cyclosporin A in autoimmune diseases

1 reference

12 December 2020

Clinically significant drug interactions with cyclosporin. An update

1 reference

12 December 2020

Is N-acetylation of 5-aminosalicylic acid reversible in man?

1 reference

12 December 2020

A placebo-controlled, double-blind, randomized trial of cyclosporine therapy in active chronic Crohn's disease.

1 reference

12 December 2020

An antibiotic regimen for the treatment of active Crohn's disease: a randomized, controlled clinical trial of metronidazole plus ciprofloxacin.

1 reference

12 December 2020

Thiol S-methylation in uremia: erythrocyte enzyme activities and plasma inhibitors

1 reference

12 December 2020

Immunosuppressive strategies in transplantation

1 reference

12 December 2020

Pharmacokinetics of ciprofloxacin after oral and parenteral administration

1 reference

12 December 2020

Requirements for intracellular accumulation and release of clarithromycin and azithromycin by human phagocytes

1 reference

12 December 2020

Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis

1 reference

12 December 2020

Dose- and time-related effect of troleandomycin on methylprednisolone elimination

1 reference

12 December 2020

Prevention of post-operative recurrence of Crohn's disease requires adequate mucosal concentration of mesalazine. Gruppo Italiano per lo Studio del Colon e del Retto

1 reference

12 December 2020

Historical origins of medical and surgical therapy of inflammatory bowel disease

1 reference

12 December 2020

Alterations in prednisolone disposition as a result of oral contraceptive use and dose

1 reference

12 December 2020

Double-blind, placebo-controlled evaluation of 5-ASA suppositories in active distal proctitis and measurement of extent of spread using 99mTc-labeled 5-ASA suppositories

1 reference

12 December 2020

Antimycobacterial therapy in Crohn's disease: results of a controlled, double-blind trial with a multiple antibiotic regimen.

1 reference

12 December 2020

Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease

1 reference

12 December 2020

Absolute oral bioavailability of ciprofloxacin

1 reference

12 December 2020

Clinical pharmacology of inflammatory bowel disease therapies

1 reference

12 December 2020

Tumour necrosis factor and Crohn's disease

1 reference

12 December 2020

Chimeric anti-tumor necrosis factor-alpha monoclonal antibody treatment of patients with rheumatoid arthritis receiving methotrexate therapy.

1 reference

12 December 2020

Update in medical therapy in inflammatory bowel disease: a clinician's view

1 reference

12 December 2020

Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver

1 reference

12 December 2020

Differences in P-glycoprotein-170 expression and activity between Crohn's disease and ulcerative colitis

1 reference

12 December 2020

A controlled double blind study of azathioprine in the management of Crohn's disease

1 reference

12 December 2020

Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders

1 reference

12 December 2020

Pharmacokinetics and dose linearity testing of methylprednisolone phosphate

1 reference

12 December 2020

Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety

1 reference

12 December 2020

Review article: older systemic and newer topical glucocorticosteroids and the gastrointestinal tract

1 reference

12 December 2020

Therapy of inflammatory bowel disease.

1 reference

12 December 2020

Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia

1 reference

12 December 2020

Thiopurine methyltransferase. Aromatic thiol substrates and inhibition by benzoic acid derivatives.

1 reference

12 December 2020

Infliximab: a review of its use in the management of rheumatoid arthritis

1 reference

12 December 2020

The absorption of low-dose methotrexate in patients with inflammatory bowel disease

1 reference

12 December 2020

Kinetics of methylprednisolone and its hemisuccinate ester

1 reference

12 December 2020

Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man

1 reference

12 December 2020

Disposition of mesalazine from mesalazine-delivering drugs in patients with inflammatory bowel disease, with and without diarrhoea

1 reference

12 December 2020

A randomized dose-response and pharmacokinetic study of methotrexate for refractory inflammatory Crohn's disease and ulcerative colitis

1 reference

12 December 2020

Methotrexate therapy in rheumatoid arthritis. Current status

1 reference

12 December 2020

Inflammatory bowel disease: etiology and pathogenesis.

1 reference

12 December 2020

Cyclosporin clinical pharmacokinetics

1 reference

12 December 2020

Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability

1 reference

12 December 2020

Frequency of glucocorticoid resistance and dependency in Crohn's disease

1 reference

12 December 2020

A dose-ranging study of azathioprine pharmacokinetics after single-dose administration of a delayed-release oral formulation

1 reference

12 December 2020

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

1 reference

12 December 2020

The role of antibiotics in Crohn's disease

1 reference

12 December 2020

Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion

1 reference

12 December 2020

Kinetics of the epimeric glucocorticoid budesonide

1 reference

12 December 2020

Clinical Pharmacokinetics of Prednisone and Prednisolone

1 reference

12 December 2020

Pharmacokinetics and oral bioavailability of hydrocortisone

1 reference

12 December 2020

Disposition of metronidazole and its effects on sulphasalazine metabolism in patients with inflammatory bowel disease

1 reference

12 December 2020

A new microemulsion formulation of cyclosporin: pharmacokinetic and clinical features

1 reference

12 December 2020

Enhanced bioavailability of azathioprine compared to 6-mercaptopurine therapy in inflammatory bowel disease: correlation with treatment efficacy

1 reference

12 December 2020

Pharmacokinetics of methylprednisolone hemisuccinate and methylprednisolone in chronic liver disease

1 reference

12 December 2020

Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia

1 reference

12 December 2020

Is there an interaction between low doses of corticosteroids and methotrexate in patients with rheumatoid arthritis? A pharmacokinetic study in 33 patients

1 reference

12 December 2020

Open label trial of oral clarithromycin in active Crohn's disease.

1 reference

12 December 2020

Comparison of high-pressure liquid chromatography and bioassay for determination of ciprofloxacin in serum and urine

1 reference

12 December 2020

Cyclosporin pharmacokinetics after intravenous and oral administration in patients with Crohn's disease

1 reference

12 December 2020

Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

1 reference

12 December 2020

A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. II. Result

1 reference

12 December 2020

Clinical pharmacokinetics of clarithromycin

1 reference

12 December 2020

10.2165/00003088-200140100-00003

Identifiers

DOI

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Dimensions Publication ID

2 August 2017

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1 reference