(Q34441561)

2 August 2017

Tracking cancer drugs in living cells by thermal profiling of the proteome (English)

1 reference

2 August 2017

10

Susan Klaeger

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Rozbeh Jafari

Rozbeh Jafari

8

0 references

Gerard Drewes

Gerard Drewes

14

0 references

Bernhard Kuster

Bernhard Kuster

11

0 references

Marcus Bantscheff

13

Marcus Bantscheff

1 reference

2 August 2017

6

Dirk Eberhard

1 reference

2 August 2017

1

Mikhail M Savitski

1 reference

2 August 2017

5

Maria Fälth Savitski

1 reference

2 August 2017

3

Holger Franken

1 reference

2 August 2017

4

Thilo Werner

1 reference

2 August 2017

Friedrich B M Reinhard

2

1 reference

2 August 2017

Daniel Martinez Molina

7

1 reference

2 August 2017

Rebecca Bakszt Dovega

9

1 reference

2 August 2017

Pär Nordlund

12

1 reference

2 August 2017

language of work or name

English

0 references

publication date

2 October 2014

1 reference

2 August 2017

1 reference

2 August 2017

346

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2 August 2017

6205

1 reference

2 August 2017

1255784

1 reference

Mass-spectrometry-based draft of the human proteome

2 August 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Quantitative, high-resolution proteomics for data-driven systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Mass spectrometry-based proteomics and network biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Direct identification of ligand-receptor interactions on living cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Determining target engagement in living systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Ion coalescence of neutron encoded TMT 10-plex reporter ions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Kinetics of protein aggregation. Quantitative estimation of the chaperone-like activity in test-systems based on suppression of protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Protein folding stability and dynamics imaged in a living cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

High-resolution enabled TMT 8-plexing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Structure and Allostery of the PKA RII Tetrameric Holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Erythroid heme biosynthesis and its disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Vemurafenib: an unusual UVA-induced photosensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Overcoming the resistance to crizotinib in patients with non-small cell lung cancer harboring EML4/ALK translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Overriding imatinib resistance with a novel ABL kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

BCR-ABL activity and its response to drugs can be determined in CD34+ CML stem cells by CrkL phosphorylation status using flow cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Comparison of imatinib, dasatinib, nilotinib and INNO-406 in imatinib-resistant cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Targeted data acquisition for improved reproducibility and robustness of proteomic mass spectrometry assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

Measuring and managing ratio compression for accurate iTRAQ/TMT quantification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

The thermodynamics of solvent exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1255784

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1255784

1 reference

2 August 2017

1 reference