(Q34459061)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609585%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors (English)

1 reference

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28 February 2020

1

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28 February 2020

Phil F Cheng

6

1 reference

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28 February 2020

Natalia Arenas-Ramirez

7

1 reference

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28 February 2020

Onur Boyman

14

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28 February 2020

Lukas Sommer

18

1 reference

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28 February 2020

17

Reinhard Dummer

1 reference

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28 February 2020

author name string

Julien Debbache

2

1 reference

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28 February 2020

Simon M Schaefer

3

1 reference

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28 February 2020

Eylul Tuncer

4

1 reference

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28 February 2020

Sandra C Frommel

5

1 reference

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28 February 2020

Jessica Haeusel

8

1 reference

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28 February 2020

Yudong Zhang

9

1 reference

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28 February 2020

Mario Bonalli

10

1 reference

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28 February 2020

Michael T McCabe

11

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28 February 2020

Caretha L Creasy

12

1 reference

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28 February 2020

Mitchell P Levesque

13

1 reference

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28 February 2020

Raffaella Santoro

15

1 reference

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28 February 2020

Olga Shakhova

16

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28 February 2020

language of work or name

English

0 references

publication date

22 January 2015

1 reference

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28 February 2020

published in

Nature Communications

1 reference

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28 February 2020

volume

6

1 reference

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28 February 2020

page(s)

6051

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https://scigraph.springernature.com/pub.10.1038/ncomms7051

28 February 2020

exact match

0 references

cites work

Cancer statistics, 2014

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Why is melanoma so metastatic?

21 January 2018

1 reference

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Tumor adaptation and resistance to RAF inhibitors

21 January 2018

1 reference

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BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling

21 January 2018

1 reference

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Neural crest stem cells in melanoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migration

21 January 2018

1 reference

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A perspective on cancer cell metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Neural crest progenitors and stem cells: from early development to adulthood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

A landscape of driver mutations in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

SOX10 Maintains Multipotency and Inhibits Neuronal Differentiation of Neural Crest Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Stability and flexibility of epigenetic gene regulation in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

21 January 2018

Epigenetics in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

The Polycomb complex PRC2 and its mark in life

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Molecular architecture of human polycomb repressive complex 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Ezh2 is required for neural crest-derived cartilage and bone formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Expression of polycomb group protein EZH2 in nevi and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

EZH2 expands breast stem cells through activation of NOTCH1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

MiR-101 inhibits melanoma cell invasion and proliferation by targeting MITF and EZH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Expression of melan-A (MART1) in benign melanocytic nevi and primary cutaneous malignant melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Epigenetic alterations in hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Signatures of mutational processes in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7051

A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7051

Melanoma invasion - current knowledge and future directions

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7051

Directed phenotype switching as an effective antimelanoma strategy.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7051

A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7051

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia.

21 January 2018

1 reference

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An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB

21 January 2018

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Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming

21 January 2018

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Testing the cancer stem cell hypothesis in melanoma: the clinics will tell

21 January 2018

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β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas

21 January 2018

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Functional significance of eIF5A and its hypusine modification in eukaryotes

21 January 2018

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A tumour suppressor network relying on the polyamine-hypusine axis

21 January 2018

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Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a component of the intraflagellar transport machinery in sensory cilia

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7051

WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence

21 January 2018

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Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition

21 January 2018

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Chromatin proteins and modifications as drug targets

21 January 2018

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Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

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Simplified mammalian DNA isolation procedure

21 January 2018

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A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth

21 January 2018

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

21 January 2018

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Analysis of chromatin composition of repetitive sequences: the ChIP-Chop assay.

21 January 2018

1 reference

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MethPrimer: designing primers for methylation PCRs

21 January 2018

1 reference

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ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

21 January 2018

1 reference

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edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

21 January 2018

1 reference

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Dominant role of the niche in melanocyte stem-cell fate determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

Metastasizing Melanoma Formation Caused by Expression of Activated N-RasQ61Kon an INK4a-Deficient Background

21 January 2018

1 reference

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Characterization of melanocyte-specific inducible Cre recombinase transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7051

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS7051

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609585%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 February 2020

ADS bibcode

2015NatCo...6.6051Z

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609585%20AND%20SRC:MED&resulttype=core&format=json