(Q34476981)

2 August 2017

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title

Pathways of apoptosis and the modulation of cell death in cancer (English)

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2 August 2017

Fisher DE

1

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2 August 2017

publication date

1 October 2001

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Hematology / Oncology Clinics of North America

2 August 2017

published in

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2 August 2017

volume

15

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2 August 2017

issue

5

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2 August 2017

page(s)

931-56, ix

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The Bcl-2 protein family: arbiters of cell survival

2 August 2017

cites work

1 reference

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7 January 2021

Human ICE/CED-3 protease nomenclature

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7 January 2021

Oncogenic activity of the c-Myc protein requires dimerization with Max.

1 reference

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7 January 2021

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

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7 January 2021

Inhibition of Bax channel-forming activity by Bcl-2

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7 January 2021

Variant Max protein, derived by alternative splicing, associates with c-Myc in vivo and inhibits transactivation

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https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Death receptors: signaling and modulation

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7 January 2021

Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

1 reference

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7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The ornithine decarboxylase gene is a transcriptional target of c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Sequence-specific DNA binding by the c-Myc protein

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Perforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

An essential domain of the c-myc protein interacts with a nuclear factor that is also required for E1A-mediated transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

BCL-2 family: regulators of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bax-independent inhibition of apoptosis by Bcl-XL.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Role of CED-4 in the activation of CED-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Regulation of lymphocyte survival by the bcl-2 gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Enhanced cell survival and tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

An intact zinc ring finger is required for tumor necrosis factor receptor-associated factor-mediated nuclear factor-kappaB activation but is dispensable for c-Jun N-terminal kinase signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

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https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Prothymosin alpha binds histones in vitro and shows activity in nucleosome assembly assay

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Essential role for caspase-8 in transcription-independent apoptosis triggered by p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Mechanisms of p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Definition of a consensus binding site for p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Genetic control of programmed cell death in the nematode C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 associates with the ras-related protein R-ras p23

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Presence of a potent transcription activating sequence in the p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Apoptosis in cancer therapy: crossing the threshold

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

High affinity DNA-binding Myc analogs: recognition by an alpha helix

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cdc25 cell-cycle phosphatase as a target of c-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Transcriptional activation by Myc is under negative control by the transcription factor AP-2

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Binding and suppression of the Myc transcriptional activation domain by p107.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Identification of a large Myc-binding protein that contains RCC1-like repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Sin3 corepressor function in Myc-induced transcription and transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Oncogenes and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Clinical implications of the p53 tumor-suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Interleukin-6- and leukemia inhibitory factor-induced terminal differentiation of myeloid leukemia cells is blocked at an intermediate stage by constitutive c-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Two cellular proteins that bind to wild-type but not mutant p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 and Bax function independently to regulate cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The cellular prion protein (PrP) selectively binds to Bcl-2 in the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Regulation of Bcl-xl channel activity by calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Solution structure of the tetrameric minimum transforming domain of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Alternative forms of Max as enhancers or suppressors of Myc-ras cotransformation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Fas-induced caspase denitrosylation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Release of cytochrome c and decrease of cytochrome c oxidase in Bax-expressing yeast cells, and prevention of these effects by coexpression of Bcl-xL

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Myc represses the growth arrest gene gadd45

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Actin cleavage by CPP-32/apopain during the development of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

p53 and cancer therapy: a double-edged sword

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caspases: killer proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caspases: the proteases of the apoptotic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Apoptosis and expression of cytotoxic T lymphocyte effector molecules in renal allografts

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Checkpoints of dueling dimers foil death wishes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

An alternative pathway for gene regulation by Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Mechanisms of apoptosis by c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Differential patterns of DNA binding by myc and max proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 and the regulation of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Direct role for Myc in transcription initiation mediated by interactions with TFII-I

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

An alternative pathway for transcription initiation involving TFII-I

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Analysis of a protein-binding domain of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

New Myc-interacting proteins: a second Myc network emerges

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Channel formation by antiapoptotic protein Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A unique glucose-dependent apoptotic pathway induced by c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bak can accelerate chemotherapy-induced cell death independently of its heterodimerization with Bcl-XL and Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Repression of p15INK4b expression by Myc through association with Miz-1

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Definition of regions in human c-myc that are involved in transformation and nuclear localization

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Substrate specificities of caspase family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Modulation of cell death in yeast by the Bcl-2 family of proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The many roles of c-Myc in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Structure and mechanism of interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

A role for c-myc in chemically induced renal-cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970258-6

7 January 2021

10.1016/S0889-8588(05)70258-6

Identifiers

DOI

1 reference

2 August 2017

1 reference