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The genetics of the E2F family of transcription factors: shared functions and unique roles
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
The genetics of the E2F family of transcription factors: shared functions and unique roles
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
author name string
James DeGregori
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
language of work or name
English
0 references
publication date
1 June 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
volume
1602
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
page(s)
131-150
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
cites work
Identification of a cellular transcription factor involved in E1A trans-activation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E2F transcription factor is a cellular target for the RB protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F target genes and cell-cycle checkpoint control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a growth suppression domain within the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rb/E2F pathway and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of E2F by pRB-family proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-6, a member of the E2F family that can behave as a transcriptional repressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An E2F-like repressor of transcription.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-5, a new E2F family member that interacts with p130 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of cdk2 Kinase with the Transcription Factor E2F During S Phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F activity is regulated by cell cycle-dependent changes in subcellular localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The subcellular localization of E2F-4 is cell-cycle dependent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex transcriptional regulatory mechanisms control expression of the E2F3 locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of E2F1 activity by acetylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F Family Members Are Differentially Regulated by Reversible Acetylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific regulation of E2F family members by cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of E2F: a family of transcription factors involved in proliferation control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F is required to prevent inappropriate S-phase entry of mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for E2F proteins in cell growth control and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple members of the E2F transcription factor family are the products of oncogenes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic capacity of the E2F1 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and E2F-1 cooperate to mediate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in fibroblasts by c-myc protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blocking the transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in SCID mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle regulation of E2F site occupation in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional antagonism between E2F family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma protein recruits histone deacetylase to repress transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma protein switches the E2F site from positive to negative element
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rb interacts with histone deacetylase to repress transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 and E1A(12S) have a homologous activation domain regulated by RB and CBP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interplay between p53 and E2F through co-activator p300.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A rough guide to a smooth brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linking the Rb and polycomb pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian chromodomain proteins: their role in genome organisation and expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rb targets histone H3 methylation and HP1 to promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active repression and E2F inhibition by pRB are biochemically distinguishable
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rb-mediated chromatin structure regulation and transcriptional repression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rb/E2F pathway: expanding roles and emerging paradigms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Target gene specificity of E2F and pocket protein family members in living cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle-dependent recruitment of HDAC-1 correlates with deacetylation of histone H4 on an Rb-E2F target promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factor E2F is required for S phase during Drosophila embryogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1 is a transcriptional target for E2F and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pocket protein-independent repression of urokinase-type plasminogen activator and plasminogen activator inhibitor 1 gene expression by E2F1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional program in the response of human fibroblasts to serum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation and function during the human cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression analysis using DNA microarrays demonstrates that E2F-1 up-regulates expression of DNA replication genes including replication protein A2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid analysis of gene expression (RAGE) facilitates universal expression profiling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Xenopus embryonic E2F is required for the formation of ventral and posterior cell fates during early embryogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA replication control through interaction of E2F-RB and the origin recognition complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear organization of DNA replication in primary mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C. elegans E2F- and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor induction and tissue atrophy in mice lacking E2F-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 functions in mice to promote apoptosis and suppress proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F4 is essential for normal erythrocyte maturation and neonatal viability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of E2F4 activity leads to abnormal development of multiple cellular lineages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunology: improving on nature in the twenty-first century
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human ARF binds E2F1 and inhibits its transcriptional activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p19ARF targets certain E2F species for degradation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for the p53 homologue p73 in E2F-1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the p53-homologue p73 in E2F1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E2F1-3 transcription factors are essential for cellular proliferation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p14ARF links the tumour suppressors RB and p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirements for cell cycle arrest by p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein is linked to the activation of Ras.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent apoptosis suppresses tumor growth and progression in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for a functional Rb-1 gene in murine development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of an Rb mutation in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of retinoblastoma protein family function by human papillomavirus type 16 E7 oncoprotein inhibits lens development in part through E2F-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc requires distinct E2F activities to induce S phase and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The paradox of E2F1: oncogene and tumor suppressor gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pRb and E2f-1 in mouse development and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of BRCA1 expression by the Rb-E2F pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 down-regulates CHK1 through p21 and the retinoblastoma protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900051-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0304-419X(02)00051-3
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
PubMed ID
12020800
1 reference
stated in
Europe PubMed Central
PubMed ID
12020800
retrieved
3 August 2017
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