(Q34752964)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Crucial role of nonspecific interactions in amyloid nucleation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Anđela Šarić

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Yassmine Chebaro

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Tuomas Knowles

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Tuomas P J Knowles

3

1 reference

PubMed ID

25453085

4 August 2017

language of work or name

English

0 references

publication date

1 December 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

17869-17874

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

Effect of the English familial disease mutation (H6R) on the monomers and dimers of Aβ40 and Aβ42

23 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

The amyloid state and its association with protein misfolding diseases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

The case for soluble Aβ oligomers as a drug target in Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Atomic structure and hierarchical assembly of a cross- amyloid fibril

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Molecular structures of amyloid and prion fibrils: consensus versus controversy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Connecting macroscopic observables and microscopic assembly events in amyloid formation using coarse grained simulations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Aggregation pathways of the amyloid β(1-42) peptide depend on its colloidal stability and ordered β-sheet stacking

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid-β forms fibrils by nucleated conformational conversion of oligomers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

A diversity of assembly mechanisms of a generic amyloid fold

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Recent progress in understanding Alzheimer's β-amyloid structures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Coarse-grained models for protein aggregation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Ion mobility-mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Nanoimaging for protein misfolding diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Direct observation of nucleation and growth in amyloid self-assembly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Determination of the free energy landscape of alpha-synuclein using spin label nuclear magnetic resonance measurements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Structure-neurotoxicity relationships of amyloid beta-protein oligomers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Effect of beta-sheet propensity on peptide aggregation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Mutations enhance the aggregation propensity of the Alzheimer's A beta peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Two-step mechanism of homogeneous nucleation of sickle cell hemoglobin polymers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

A century-old debate on protein aggregation and neurodegeneration enters the clinic

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Nanoimaging for protein misfolding and related diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Protein misfolding, functional amyloid, and human disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Structure of the cross-beta spine of amyloid-like fibrils

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Folding proteins in fatal ways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Protein folding and misfolding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Mixtures of wild-type and a pathogenic (E22G) form of Abeta40 in vitro accumulate protofibrils, including amyloid pores.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Exploring protein aggregation and self-propagation using lattice models: phase diagram and kinetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Structure determination of micelle-like intermediates in amyloid beta -protein fibril assembly by using small angle neutron scattering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Hierarchical self-assembly of chiral rod-like molecules as a model for peptide beta -sheet tapes, ribbons, fibrils, and fibers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Amyloid fibrils from muscle myoglobin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Nucleated conformational conversion and the replication of conformational information by a prion determinant

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Kinetic theory of fibrillogenesis of amyloid beta-protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Kinetics and Mechanism of Deoxyhemoglobin S Gelation: A New Approach to Understanding Sickle Cell Disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273401

Two-step nucleation of amyloid fibrils: omnipresent or not?

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Soluble amyloid Abeta-(1-40) exists as a stable dimer at low concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Amyloid beta-protein: monomer structure and early aggregation states of Abeta42 and its Pro19 alloform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Elucidation of amyloid beta-protein oligomerization mechanisms: discrete molecular dynamics study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

pH changes the aggregation propensity of amyloid-β without altering the monomer conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Alternate aggregation pathways of the Alzheimer beta-amyloid peptide: Abeta association kinetics at endosomal pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

pH-Dependent Amyloid and Protofibril Formation by the ABri Peptide of Familial British Dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Dissecting the assembly of Abeta16-22 amyloid peptides into antiparallel beta sheets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Structural and Thermodynamic Characteristics That Seed Aggregation of Amyloid-β Protein in Water.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Enhancement of Protein Crystal Nucleation by Critical Density Fluctuations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

From Molecular to Supramolecular Amyloid Structures: Contributions from Fiber Diffraction and Electron Microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Factors Governing Fibrillogenesis of Polypeptide Chains Revealed by Lattice Models

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1410159111

Evidence of the existence of micelles in the fibrillogenesis of beta-amyloid peptide

21 January 2018

1 reference

12 December 2020

Pathways and intermediates of amyloid fibril formation

1 reference

12 December 2020

Charge alterations of E22 enhance the pathogenic properties of the amyloid beta-protein

1 reference

12 December 2020

Pathogenic effects of D23N Iowa mutant amyloid beta -protein

1 reference

12 December 2020

A theory of linear and helical aggregations of macromolecules

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1410159111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

0 references

1 reference

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453085%20AND%20SRC:MED&resulttype=core&format=json