(Q34889802)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Identification of small molecule inhibitors of p27(Kip1) ubiquitination by high-throughput screening (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

main subject

protein ubiquitination

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Yushi Futamura

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

S F Sulaiman

4

1 reference

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6 March 2020

author name string

Li-Ching Ooi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Ibrahim Darah

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Hiroyuki Osada

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

publication date

6 September 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

104

1 reference

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6 March 2020

issue

11

1 reference

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6 March 2020

page(s)

1461-1467

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23910095%20AND%20SRC:MED&resulttype=core&format=json

Inhibitors of mammalian G1 cyclin-dependent kinases

6 March 2020

cites work

1 reference

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

21 January 2018

1 reference

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

21 January 2018

1 reference

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

21 January 2018

1 reference

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

1 reference

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation.

21 January 2018

1 reference

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

21 January 2018

1 reference

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

1 reference

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

1 reference

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

21 January 2018

1 reference

Skp2-mediated degradation of p27 regulates progression into mitosis

21 January 2018

1 reference

Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer

21 January 2018

1 reference

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

Role of the F-box protein Skp2 in lymphomagenesis

21 January 2018

1 reference

Gene therapy for human small-cell lung carcinoma by inactivation of Skp-2 with virally mediated RNA interference

21 January 2018

1 reference

Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells

21 January 2018

1 reference

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells.

21 January 2018

1 reference

Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

21 January 2018

1 reference

A green-emitting fluorescent protein from Galaxeidae coral and its monomeric version for use in fluorescent labeling

21 January 2018

1 reference

Screening of cell cycle inhibitors from microbial metabolites by a bioassay using a mouse cdc2 mutant cell line, tsFT210.

21 January 2018

1 reference

Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase

21 January 2018

1 reference

Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition

21 January 2018

1 reference

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

21 January 2018

1 reference

The metabolism and mode of action of gentian violet

21 January 2018

1 reference

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

21 January 2018

1 reference

21 January 2018

1 reference

Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.

21 January 2018

1 reference

12 December 2020

Isolation and analysis of a mammalian temperature-sensitive mutant defective in G2 functions

1 reference

12 December 2020

High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas

1 reference

12 December 2020

Expression of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate

1 reference

12 December 2020

Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas

1 reference

12 December 2020

Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma

1 reference

12 December 2020

Regulation of the cdk inhibitor p27 and its deregulation in cancer

1 reference

12 December 2020

A point mutation in C-terminal region of cdc2 kinase causes a G2-phase arrest in a mouse temperature-sensitive FM3A cell mutant

1 reference

12 December 2020

Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer

1 reference

12 December 2020

Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation

1 reference

12 December 2020