(Q35053727)

6 August 2017

title

Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy (English)

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6 August 2017

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Tara L Spires-Jones

8

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Bradley Hyman

series ordinal

7

object named as

Bradley T Hyman

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6 August 2017

6

Rebecca A Betensky

1 reference

6 August 2017

2

Susanne Wegmann

1 reference

6 August 2017

Katherine J Kopeikina

series ordinal

1

object named as

Katherine J Kopeikina

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6 August 2017

3

Rose Pitstick

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6 August 2017

4

George A Carlson

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6 August 2017

5

Brian J Bacskai

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6 August 2017

language of work or name

English

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publication date

20 November 2013

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6 August 2017

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6 August 2017

volume

8

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6 August 2017

issue

11

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6 August 2017

page(s)

e80834

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Creative Commons Attribution 3.0 Unported

6 August 2017

copyright license

start time

20 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3835324/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Electrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathy

8 July 2018

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8 July 2018

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8 July 2018

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Early calcium dysregulation in Alzheimer's disease: setting the stage for synaptic dysfunction

8 July 2018

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Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

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Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

8 July 2018

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8 July 2018

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A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.

8 July 2018

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Caspase activation precedes and leads to tangles

8 July 2018

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Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

8 July 2018

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Is abnormal axonal transport a cause, a contributing factor or a consequence of the neuronal pathology in Alzheimer's disease?

8 July 2018

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8 July 2018

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Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs

8 July 2018

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8 July 2018

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Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease

8 July 2018

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The role of tau in neurodegeneration

8 July 2018

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Tau pathophysiology in neurodegeneration: a tangled issue

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells

8 July 2018

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Differential regulation of dynein and kinesin motor proteins by tau

8 July 2018

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Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: neurofilaments attenuate tau-mediated neurite instability

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).

8 July 2018

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Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

8 July 2018

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Tau suppression in a neurodegenerative mouse model improves memory function

8 July 2018

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Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins.

8 July 2018

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Synaptic slaughter in Alzheimer's disease

8 July 2018

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Alteration in calcium channel properties is responsible for the neurotoxic action of a familial frontotemporal dementia tau mutation

8 July 2018

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Neuronal and glial calcium signaling in Alzheimer's disease

8 July 2018

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Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Imaging amyloid-beta deposits in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Ca(2+) signaling in dendritic spines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Structural correlates of cognition in dementia: quantification and assessment of synapse change.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

The 3'-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Calcium hypothesis of Alzheimer's disease and brain aging.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Quantitative assessment of cortical synaptic density in Alzheimer's disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3835324

Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0080834

Aβ Oligomers Cause Localized Ca2+Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0080834

Calcium signalling and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0080834

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0080834

Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0080834

A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0080834

Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0080834

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24278327

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0080834

1 reference

6 August 2017

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1 reference

6 August 2017

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