(Q35062461)

6 August 2017

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title

Chemotherapy response and resistance (English)

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6 August 2017

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Soyoung Lee

1

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6 August 2017

Clemens A Schmitt

series ordinal

2

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6 August 2017

publication date

1 February 2003

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Current Opinion in Genetics & Development

6 August 2017

published in

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6 August 2017

volume

13

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6 August 2017

issue

1

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6 August 2017

page(s)

90-96

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Apoptosis: a link between cancer genetics and chemotherapy

6 August 2017

cites work

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7 January 2021

A unified view of the DNA-damage checkpoint

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7 January 2021

Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

1 reference

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7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

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7 January 2021

Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

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7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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7 January 2021

The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

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7 January 2021

Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

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7 January 2021

p16INK4A participates in a G1 arrest checkpoint in response to DNA damage

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7 January 2021

Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shortening

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7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021

Oncogenic ras and p53 cooperate to induce cellular senescence

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7 January 2021

Microarray analysis of replicative senescence

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7 January 2021

Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts

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7 January 2021

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

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7 January 2021

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

1 reference

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7 January 2021

Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

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7 January 2021

p19ARF links the tumour suppressor p53 to Ras

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7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

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7 January 2021

Oncogene-dependent apoptosis in extracts from drug-resistant cells

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7 January 2021

Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death

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7 January 2021

Apaf-1 is a transcriptional target for E2F and p53

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7 January 2021

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

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7 January 2021

Direct coupling of the cell cycle and cell death machinery by E2F.

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7 January 2021

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest

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7 January 2021

Genetic analysis of chemoresistance in primary murine lymphomas.

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7 January 2021

DNA damage responses and chemosensitivity in the E mu-myc mouse lymphoma model.

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7 January 2021

Apoptosis and chemoresistance in transgenic cancer models

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7 January 2021

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

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7 January 2021

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

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7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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7 January 2021

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

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7 January 2021

Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

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7 January 2021

Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes

1 reference

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7 January 2021

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

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7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

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7 January 2021

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

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7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

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7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

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7 January 2021

Dissecting p53 tumor suppressor functions in vivo

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7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

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7 January 2021

Hemizygous p16(INK4A) deletion in pediatric acute lymphoblastic leukemia predicts independent risk of relapse

1 reference

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7 January 2021

Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.

1 reference

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7 January 2021

Pharmacological rescue of mutant p53 conformation and function

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7 January 2021

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

1 reference

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7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

1 reference

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7 January 2021

Pifithrin-alpha, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP16) in human lymphoblastoid cells treated in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900014-X

7 January 2021

10.1016/S0959-437X(02)00014-X

Identifiers

DOI

1 reference

6 August 2017

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