(Q35136164)

6 August 2017

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title

The mammalian XRCC genes: their roles in DNA repair and genetic stability (English)

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6 August 2017

author

Małgorzata Z Zdzienicka

series ordinal

2

object named as

Małgorzata Z Zdzienicka

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6 August 2017

John Thacker

1

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6 August 2017

publication date

1 June 2003

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6 August 2017

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6 August 2017

volume

2

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6 August 2017

issue

6

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6 August 2017

page(s)

655-672

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A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange

6 August 2017

cites work

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7 January 2021

Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

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7 January 2021

Mutagen-sensitive cell lines are obtained with a high frequency in V79 Chinese hamster cells.

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7 January 2021

An ionizing radiation-sensitive mutant of CHO cells: irs-20. I. Isolation and initial characterization.

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7 January 2021

A novel type of X-ray-sensitive Chinese hamster cell mutant with radioresistant DNA synthesis and hampered DNA double-strand break repair

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7 January 2021

A CHO mutant, UV40, that is sensitive to diverse mutagens and represents a new complementation group of mitomycin C sensitivity.

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7 January 2021

The genetic basis of resistance to ionising radiation damage in cultured mammalian cells.

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7 January 2021

Genetic analysis of ionising radiation sensitive mutants of cultured mammalian cell lines

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7 January 2021

Functional Complementation Studies with X-ray-sensitive Mutants of Chinese Hamster Cells Closely Resembling Ataxia-telangiectasia Cells.

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7 January 2021

Interspecific complementation between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation

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7 January 2021

Nomenclature of human genes involved in ionizing radiation sensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Methyl methanesulfonate-induced hprt mutation spectra in the Chinese hamster cell line CHO9 and its xrcc1-deficient derivative EM-C11.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Requirement for the Xrcc1 DNA base excision repair gene during early mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Altered DNA ligase III activity in the CHO EM9 mutant

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Solution structure of the single-strand break repair protein XRCC1 N-terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC1 keeps DNA from getting stranded

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Cytogenetic characterization of the ionizing radiation-sensitive Chinese hamster mutant irs1.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Increased frequency of formation of interphase ring-chromosomes in radiosensitive irs-1 cells exposed to X-rays

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Gene mutation and V(D)J recombination in the radiosensitive irs lines

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The XRCC2 DNA repair gene: identification of a positional candidate

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A surfeit of RAD51-like genes?

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Biochemical and genetic analysis of the Chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC3 is required for efficient repair of chromosome breaks by homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Identification of a novel human RAD51 homolog, RAD51B

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Identification and purification of two distinct complexes containing the five RAD51 paralogs

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Xrcc3 is required for assembly of Rad51 complexes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Evidence for simultaneous protein interactions between human Rad51 paralogs

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XRCC3 controls the fidelity of homologous recombination: roles for XRCC3 in late stages of recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Cell cycle-dependent repair of double-strand DNA breaks in a gamma-ray-sensitive Chinese hamster cell

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Increased sensitivity to killing by restriction enzymes in the XR-1 DNA double-strand break repair-deficient mutant

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Functional complementation of the radiation-sensitive mutant M10 cell line by human chromosome 5.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Molecular characterization of ionizing radiation-hypersensitive mutant M10 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A novel mutant of mouse lymphoma cells sensitive to alkylating agents and caffeine

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

X-ray-sensitive mutant mouse cells with various sensitivities to chemical mutagens

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A mouse-cell mutant sensitive to ionizing radiation is hypermutable by low doses of γ-radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Characteristics of gamma-ray-induced chromosomal aberrations in mutagen-sensitive mutants of L5178Y cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Reparability of DNA Double-strand Breaks and Radiation Sensitivity in Five Mammalian Cell Lines

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Identification of a mutated DNA ligase IV gene in the X-ray-hypersensitive mutant SX10 of mouse FM3A cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Gene recombination in X-ray-sensitive hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Isolation of mammalian cell mutants that are X-ray sensitive, impaired in DNA double-strand break repair and defective for V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Molecular and biochemical characterization of new X-ray-sensitive hamster cell mutants defective in Ku80.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Molecular and biochemical characterization of xrs mutants defective in Ku80.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The scid mutation in mice causes a general defect in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A link between double-strand break-related repair and V(D)J recombination: the scid mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Cell cycle responses of two X-ray sensitive mutants defective in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A new X-ray sensitive CHO cell mutant of ionizing radiation group 7,XR-C2, that is defective in DSB repair but has only a mild defect in V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

DNA-PKcs mutations in dogs and horses: allele frequency and association with neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

SCID in Jack Russell terriers: a new animal model of DNA-PKcs deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku autoantigen: a multifunctional DNA-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku recruits the XRCC4-ligase IV complex to DNA ends

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Non-homologous end-joining: bacteria join the chromosome breakdance

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku acts in a unique way at the mammalian telomere to prevent end joining

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Deletion of Ku86 causes early onset of senescence in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

A human severe combined immunodeficiency (SCID) condition with increased sensitivity to ionizing radiations and impaired V(D)J rearrangements defines a new DNA recombination/repair deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Signal joint formation is also impaired in DNA-dependent protein kinase catalytic subunit knockout cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Coding end sequence can markedly affect the initiation of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The joining of non-complementary DNA double-strand breaks by mammalian extracts

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Ku86 is essential in human somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia mutated-dependent fashion

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Cellular characteristics of Chinese hamster cell mutants resembling ataxia telangiectasia cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The defect in the AT-like hamster cell mutants is complemented by mouse chromosome 9 but not by any of the human chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Human chromosome 11 complements ataxia-telangiectasia cells but does not complement the defect in AT-like Chinese hamster cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Isolation of camptothecin-sensitive chinese hamster cell mutants: phenotypic heterogeneity within the ataxia telangiectasia-like XRCC8 (irs2) complementation group

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

DNA damaging and cell cycle effects of the topoisomerase I poison camptothecin in irradiated human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The Fanconi anaemia group G gene FANCG is identical with XRCC9

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

1 reference

7 January 2021

The emerging genetic and molecular basis of Fanconi anaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

The Fanconi anaemia/BRCA pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Breast cancer and Fanconi anemia: what are the connections?

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Impaired DNA damage-induced nuclear Rad51 foci formation uniquely characterizes Fanconi anemia group D1

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Attenuation of the formation of DNA-repair foci containing RAD51 in Fanconi anaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Biallelic inactivation of BRCA2 in Fanconi anemia

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Chromosome stability, DNA recombination and the BRCA2 tumour suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Involvement of Brca2 in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

On the nature of hereditable variation in cultured somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Nucleotide excision repair. II: From yeast to mammals

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

How nucleotide excision repair protects against cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Variants in DNA double-strand break repair genes and breast cancer susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

Genetic analysis of mitomycin C-hypersensitive Chinese hamster cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900062-4

7 January 2021

10.1016/S1568-7864(03)00062-4

Identifiers

DOI

1 reference

6 August 2017

1 reference