(Q35185164)

7 August 2017

title

Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to Analysis (English)

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7 August 2017

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2

Marylyn D Ritchie

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7 August 2017

Benjamin J Grady

1

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7 August 2017

language of work or name

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1 March 2011

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Current Pharmacogenomics and Personalized Medicine: the international journal for expert reviews in pharmacogenomics

7 August 2017

published in

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7 August 2017

volume

9

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7 August 2017

issue

1

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7 August 2017

page(s)

41-66

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Quality control procedures for genome-wide association studies

7 August 2017

cites work

1 reference

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The Archon Genomics X PRIZE for whole human genome sequencing

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Quality control and quality assurance in genotypic data for genome-wide association studies

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data

13 July 2018

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A new approach to long QT syndrome mutation detection by Sequenom MassARRAY system

13 July 2018

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The genetics of multiple sclerosis: an update 2010.

13 July 2018

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FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals

13 July 2018

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Clinical implementation of pharmacogenomics: overcoming genetic exceptionalism

13 July 2018

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Genetic heterogeneity in human disease

13 July 2018

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Role of warfarin pharmacogenetic testing in clinical practice

13 July 2018

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High content screening: seeing is believing.

13 July 2018

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Quality control for genome-wide association studies

13 July 2018

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ProbABEL package for genome-wide association analysis of imputed data

13 July 2018

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Methods for optimizing statistical analyses in pharmacogenomics research

13 July 2018

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The 1000 Genomes Project: new opportunities for research and social challenges

13 July 2018

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Laboratory methods for high-throughput genotyping.

13 July 2018

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13 July 2018

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GWAS analyzer: integrating genotype, phenotype and public annotation data for genome-wide association study analysis

13 July 2018

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Tag SNP selection using particle swarm optimization

13 July 2018

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Case-only gene-environment interaction studies: when does association imply mechanistic interaction?

13 July 2018

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Clinical pharmacology and pharmacogenetics in a genomics era: the DMET platform.

13 July 2018

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Expectations, validity, and reality in pharmacogenetics

13 July 2018

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Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox

13 July 2018

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Genome-wide association analyses of quantitative traits: the GAW16 experience

13 July 2018

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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

13 July 2018

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Finding unique filter sets in PLATO: a precursor to efficient interaction analysis in GWAS data

13 July 2018

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Genetic diagnosis by whole exome capture and massively parallel DNA sequencing

13 July 2018

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Finding the missing heritability of complex diseases

13 July 2018

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Spatially uniform relieff (SURF) for computationally-efficient filtering of gene-gene interactions

13 July 2018

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Bayesian statistical methods for genetic association studies

13 July 2018

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13 July 2018

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Targeted capture and massively parallel sequencing of 12 human exomes

13 July 2018

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Single-molecule sequencing of an individual human genome

13 July 2018

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Failure to replicate a genetic association may provide important clues about genetic architecture

13 July 2018

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Common vs. rare allele hypotheses for complex diseases

13 July 2018

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

13 July 2018

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13 July 2018

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Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm

13 July 2018

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Validating, augmenting and refining genome-wide association signals

13 July 2018

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Validation of clinical testing for warfarin sensitivity: comparison of CYP2C9-VKORC1 genotyping assays and warfarin-dosing algorithms.

13 July 2018

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13 July 2018

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A new wave in the genetics of psychiatric disorders: the copy number variant tsunami

13 July 2018

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Cytochrome p-450 polymorphisms and response to clopidogrel

13 July 2018

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The combined effect of SNP-marker and phenotype attributes in genome-wide association studies

13 July 2018

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SNP-guided microRNA maps (MirMaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways

13 July 2018

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Personal genomes: The case of the missing heritability

13 July 2018

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SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system

13 July 2018

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Economic methods for valuing the outcomes of genetic testing: beyond cost-effectiveness analysis

13 July 2018

1 reference

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Role of cytochrome P450 in drug interactions

13 July 2018

1 reference

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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

13 July 2018

1 reference

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Accounting for ancestry: population substructure and genome-wide association studies

13 July 2018

1 reference

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Next-generation DNA sequencing

13 July 2018

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Efficient association study design via power-optimized tag SNP selection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Pharmacogenetics of immunosuppressive drugs: prospect of individual therapy for transplant patients

13 July 2018

1 reference

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A HapMap harvest of insights into the genetics of common disease

13 July 2018

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Linkage disequilibrium--understanding the evolutionary past and mapping the medical future

13 July 2018

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Genome-wide association studies for complex traits: consensus, uncertainty and challenges

13 July 2018

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Methods for handling multiple testing

13 July 2018

1 reference

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Prioritize and select SNPs for association studies with multi-stage designs

13 July 2018

1 reference

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HLA-B*5701 screening for hypersensitivity to abacavir

13 July 2018

1 reference

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A second generation human haplotype map of over 3.1 million SNPs

13 July 2018

1 reference

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Novel methods for detecting epistasis in pharmacogenomics studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Mendelian proportions in a mixed population

13 July 2018

1 reference

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PLINK: a tool set for whole-genome association and population-based linkage analyses

13 July 2018

1 reference

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A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Limitations of the randomized controlled trial in evaluating population-based health interventions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Case-control association testing with related individuals: a more powerful quasi-likelihood score test

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Appearances can be deceiving: phenotypes of knockout mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Replicating genotype-phenotype associations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Non-replication and inconsistency in the genome-wide association setting

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Systematic prediction and validation of breakpoints associated with copy-number variants in the human genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

A simple and improved correction for population stratification in case-control studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

GenABEL: an R library for genome-wide association analysis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Anticipating the 1,000 dollar genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Genes, environment and the value of prospective cohort studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

A tutorial on statistical methods for population association studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Principal components analysis corrects for stratification in genome-wide association studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Human genetic variability and HIV treatment response

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Multifactor dimensionality reduction: an analysis strategy for modelling and detecting gene-gene interactions in human genetics and pharmacogenomics studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

GPNN: power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease

13 July 2018

1 reference

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Using linkage genome scans to improve power of association in genome scans

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Confounding from cryptic relatedness in case-control association studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Mapping quantitative trait loci in humans: achievements and limitations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Complement factor H polymorphism in age-related macular degeneration

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Complement factor H polymorphism and age-related macular degeneration

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Complement factor H variant increases the risk of age-related macular degeneration

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The epidemiologic approach to pharmacogenomics

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Pharmacogenetics and enzyme induction/inhibition properties of antiepileptic drugs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Randomized controlled trials

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Finishing the euchromatic sequence of the human genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Statistical tests for admixture mapping with case-control and cases-only data

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Large-scale copy number polymorphism in the human genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Preventing and managing antiretroviral drug resistance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Mapping complex disease loci in whole-genome association studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Capn5 is expressed in a subset of T cells and is dispensable for development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Reporting of model validation procedures in human studies of genetic interactions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The International HapMap Project

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Patterns of Human Genetic Diversity: Implications for Human Evolutionary History and Disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

A SYSTEM FOR PHENOTYPING HYPERLIPOPROTEINEMIA.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Control of confounding of genetic associations in stratified populations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The Human Genome Project: Lessons from Large-Scale Biology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Modeling medical prognosis: survival analysis techniques

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Functional profiling of the Saccharomyces cerevisiae genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

A perspective on epistasis: limits of models displaying no main effect

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Replication validity of genetic association studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Genomic control for association studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Initial sequencing and analysis of the human genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Arabidopsis gene knockout: phenotypes wanted

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The protein-protein interaction map of Helicobacter pylori

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The pharmacokinetics and metabolic disposition of tacrolimus: a comparison across ethnic groups

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Accounting for unmeasured population substructure in case-control studies of genetic association using a novel latent-class model

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Inference of population structure using multilocus genotype data

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Association mapping in structured populations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Molecular genetics of Alzheimer's disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Use of unlinked genetic markers to detect population stratification in association studies.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

PCR-based DNA amplification and presumptive detection of Escherichia coli O157:H7 with an internal fluorogenic probe and the 5' nuclease (TaqMan) assay

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Functional analysis of the genes of yeast chromosome V by genetic footprinting

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Defining the clinical course of multiple sclerosis: Results of an international survey

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Nontraditional epidemiologic approaches in the analysis of gene-environment interaction: case-control studies with no controls!

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Why we need observational studies to evaluate the effectiveness of health care

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Construction of a genetic linkage map in man using restriction fragment length polymorphisms

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Multiple linear regression is a useful alternative to traditional analyses of variance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Factors affecting the maintenance dose of warfarin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

SNP selection in genome-wide and candidate gene studies via penalized logistic regression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

ATHENA: A knowledge-based hybrid backpropagation-grammatical evolution neural network algorithm for discovering epistasis among quantitative trait Loci

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The long and winding road to warfarin pharmacogenetic testing.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Envisioning the future of early anticancer drug development.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

VEGF -460T → C polymorphism and its association with VEGF expression and outcome to FOLFOX-4 treatment in patients with colorectal carcinoma

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo Warfarin Effectiveness study).

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

DMET microarray technology for pharmacogenomics-based personalized medicine

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Genetic and clinical predictors of warfarin dose requirements in African Americans

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Impact of CYP3A5 and CYP3A4 gene polymorphisms on dose requirement of calcineurin inhibitors, cyclosporine and tacrolimus, in renal allograft recipients of North India

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Validation of VKORC1 and CYP2C9 genotypes on interindividual warfarin maintenance dose: a prospective study in Chinese patients

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Factors responsible for inter-individual variations in dosage/concentration of tacrolimus in renal transplant recipients

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

A comparison of analytical methods for genetic association studies

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Examining population stratification via individual ancestry estimates versus self-reported race

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Rational inferences about departures from Hardy-Weinberg equilibrium

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Genome-wide strategies for detecting multiple loci that influence complex diseases.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The impact of pharmacogenomic factors on steroid dependency in pediatric heart transplant patients using logistic regression analysis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Hox transcription factor ultrabithorax Ib physically and genetically interacts with disconnected interacting protein 1, a double-stranded RNA-binding protein.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

CYP2D6*10 alleles do not determine plasma fluvoxamine concentration/dose ratio in Japanese subjects

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Candidate-gene approaches for studying complex genetic traits: practical considerations

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Sequence analysis using logic regression.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Tumor necrosis factor-alpha promoter variant 2 (TNF2) is associated with pre-term delivery, infant mortality, and malaria morbidity in western Kenya: Asembo Bay Cohort Project IX.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Reevaluation of the confounding effect of cigarette smoking on the relationship between alcohol use and lung cancer risk, with larynx cancer used as a positive control

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

The design of case-control studies: the influence of confounding and interaction effects.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Understanding the Evolutionary Process of Grammatical Evolution Neural Networks for Feature Selection in Genetic Epidemiology

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163263

Variations on a theme: cataloging human DNA sequence variation

25 October 2018

1 reference

12 December 2020

Whole-genome sequencing breaks the cost barrier

1 reference

12 December 2020

Cytochrome P-450 polymorphisms and response to clopidogrel

1 reference

12 December 2020

Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice

1 reference

12 December 2020

A complete enumeration and classification of two-locus disease models

1 reference

12 December 2020

1 reference

12 December 2020

Pharmacogenomic associations in ABCB1 and CYP3A5 with acute kidney injury and chronic kidney disease after myeloablative hematopoietic cell transplantation

1 reference

12 December 2020

Cystic fibrosis in Chilean patients: Analysis of 36 common CFTR gene mutations

1 reference

12 December 2020

The new genomics: global views of biology

1 reference

12 December 2020

Plasma levels of antiepileptic drugs in children on the ketogenic diet

1 reference

12 December 2020

Editorial expression of concern

1 reference

12 December 2020

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

1 reference

12 December 2020

The P-value illusion: how to improve (psychiatric) genetic studies

1 reference

12 December 2020

Identifying interacting SNPs using Monte Carlo logic regression

1 reference

12 December 2020

10.2174/187569211794728805

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference