(Q35205434)

7 August 2017

title

Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1. (English)

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7 August 2017

2

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7 August 2017

3

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7 August 2017

Si-Cai Zhang

1

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7 August 2017

Petra Janning

4

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7 August 2017

Aliaksei Shymanets

5

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7 August 2017

Ion C Cirstea

6

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7 August 2017

Eberhard Krause

7

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7 August 2017

Bernd Nürnberg

8

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7 August 2017

Mohammad Reza Ahmadian

9

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7 August 2017

language of work or name

English

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publication date

11 July 2014

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7 August 2017

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7 August 2017

volume

9

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7 August 2017

issue

7

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7 August 2017

page(s)

e102425

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Creative Commons Attribution 4.0 International

7 August 2017

copyright license

start time

11 July 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI

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A palmitoylation switch mechanism regulates Rac1 function and membrane organization.

13 July 2018

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Chemical biology of lipidated proteins

13 July 2018

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The p101 subunit of PI3Kγ restores activation by Gβ mutants deficient in stimulating p110γ.

13 July 2018

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Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

13 July 2018

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The 'invisible hand': regulation of RHO GTPases by RHOGDIs

13 July 2018

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Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size

13 July 2018

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Membrane binding of lipidated Ras peptides and proteins--the structural point of view

13 July 2018

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Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation

13 July 2018

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Mammalian Rho GTPases: new insights into their functions from in vivo studies

13 July 2018

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Crucial structural role for the PH and C1 domains of the Vav1 exchange factor

13 July 2018

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Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.

13 July 2018

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Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane

13 July 2018

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Membrane-dependent signal integration by the Ras activator Son of sevenless

13 July 2018

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Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Assembly and trafficking of heterotrimeric G proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Geranylgeranyltransferase I as a target for anti-cancer drugs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Current knowledge of the large RhoGAP family of proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

In vivo dynamics of Rac-membrane interactions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Spatiotemporal regulation of the Pak1 kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

GDIs: central regulatory molecules in Rho GTPase activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Always look on the bright site of Rho: structural implications for a conserved intermolecular interface

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Rho-family GTPases: it's not only Rac and Rho (and I like it).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Rho and Rac take center stage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Regulation of Tiam1-Rac signalling.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Rho GTPases in cell biology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Crystal structure of the Rac1-RhoGDI complex involved in nadph oxidase activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Rho GTPases and their effector proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Structure of Cdc42 bound to the GTPase binding domain of PAK

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

A novel role for RhoGDI as an inhibitor of GAP proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Identification of a novel mouse Dbl proto-oncogene splice variant: evidence that SEC14 domain is involved in GEF activity regulation.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Interaction characteristics of Plexin-B1 with Rho family proteins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Mapping the isoprenoid binding pocket of PDEdelta by a semisynthetic, photoactivatable N-Ras lipoprotein

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Comparative functional analysis of the Rac GTPases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Titration of non-occluded baculovirus using a cell viability assay

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Role of prenylation in the interaction of Rho-family small GTPases with GTPase activating proteins.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Activation of the O2(-)-generating NADPH oxidase in a semi-recombinant cell-free system. Assessment of the function of Rac in the activation process

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094549

Rho GTPases and their effector proteins

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102425

Dissociation of the K-Ras4B/PDEδ Complex upon Contact with Lipid Membranes: Membrane Delivery Instead of Extraction

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102425

Phosphoinositide-dependent activation of Rho A involves partial opening of the RhoA/Rho-GDI complex

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102425

An electrostatic steering mechanism of Cdc42 recognition by Wiskott-Aldrich syndrome proteins

21 January 2018

1 reference

12 December 2020

p190-RhoGAP as an integral component of the Tiam1/Rac1-induced downregulation of Rho

1 reference

12 December 2020

Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly

1 reference

12 December 2020

Phospholipid-binding properties of bovine factor V and factor Va

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12 December 2020

Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer

1 reference

12 December 2020

New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0102425

Identifiers

DOI

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7 August 2017

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7 August 2017

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