(Q35278303)

7 August 2017

title

Diversity-oriented synthesis of drug-like macrocyclic scaffolds using an orthogonal organo- and metal catalysis strategy (English)

1 reference

7 August 2017

Sean Bartlett

2

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David R. Spring

object named as

David R Spring

series ordinal

5

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James T Hodgkinson

object named as

James T Hodgkinson

series ordinal

4

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Matej Janecek

series ordinal

3

object named as

Matej Janecek

1 reference

7 August 2017

André Grossmann

1

1 reference

7 August 2017

language of work or name

English

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publication date

26 September 2014

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Angewandte Chemie International Edition

7 August 2017

published in

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volume

53

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7 August 2017

issue

48

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7 August 2017

page(s)

13093-13097

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Biology-inspired synthesis of compound libraries

7 August 2017

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A small molecule that binds Hedgehog and blocks its signaling in human cells

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Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

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Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

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Diversity-oriented synthesis as a tool for identifying new modulators of mitosis.

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Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles

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A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds

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A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling

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Macrocycles in new drug discovery

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Exploiting Acyl and Enol Azolium Intermediates via NHeterocyclic Carbene Catalyzed Reactions of Alpha-Reducible Aldehydes

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21 January 2018

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Asymmetric intermolecular Stetter reactions catalyzed by a novel triazolium derived N-heterocyclic carbene.

21 January 2018

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Enantio- and diastereoselective intermolecular Stetter reaction of glyoxamide and alkylidene ketoamides

21 January 2018

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Catalytic asymmetric intermolecular stetter reaction of heterocyclic aldehydes with nitroalkenes: backbone fluorination improves selectivity

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to gamma-lactams

21 January 2018

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Multicatalytic, asymmetric Michael/Stetter reaction of salicylaldehydes and activated alkynes

21 January 2018

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Lewis acid activated synthesis of highly substituted cyclopentanes by the N-heterocyclic carbene catalyzed addition of homoenolate equivalents to unsaturated ketoesters

21 January 2018

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N-heterocyclic-carbene-catalyzed one-pot synthesis of hydroxamic esters

21 January 2018

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A simple recipe for sophisticated cocktails: organocatalytic one-pot reactions--concept, nomenclature, and future perspectives

21 January 2018

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Cooperative Lewis acid/N-heterocyclic carbene catalysis

21 January 2018

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Metal and carbene organocatalytic relay activation of alkynes for stereoselective reactions.

21 January 2018

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Natural product–inspired cascade synthesis yields modulators of centrosome integrity

21 January 2018

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21 January 2018

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Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

21 January 2018

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Hoch enantioselektive Synthese von α-Aminosäurederivaten durch NHC-katalysierte intermolekulare Stetter-Reaktion

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANIE.201406865

1 reference

7 August 2017

1 reference