(Q35631836)

English

Up-regulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioural deficits in a putative mouse model of post-traumatic stress disorder

scientific article published on January 2012

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

Up-regulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioural deficits in a putative mouse model of post-traumatic stress disorder (English)

1 reference

Europe PubMed Central

9 August 2017

post-traumatic stress disorder

0 references

1

object named as

Graziano Pinna

1 reference

Europe PubMed Central

9 August 2017

Ann M. Rasmusson

2

object named as

Ann M Rasmusson

1 reference

Europe PubMed Central

9 August 2017

publication date

1 January 2012

1 reference

Europe PubMed Central

9 August 2017

Journal of Neuroendocrinology

1 reference

Europe PubMed Central

9 August 2017

24

1 reference

Europe PubMed Central

9 August 2017

1

1 reference

Europe PubMed Central

9 August 2017

102-116

1 reference

Europe PubMed Central

9 August 2017

Experience dictates stem cell fate in the adult hippocampus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Effects of gonadal steroids in women with a history of postpartum depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Neurosteroids: biosynthesis and function of these novel neuromodulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Running enhances neurogenesis, learning, and long-term potentiation in mice

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Treatment of recent trauma survivors with benzodiazepines: a prospective study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Effects of antidepressant treatment on neuroactive steroids in major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Closer to neurogenesis in adult humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Progesterone metabolite allopregnanolone in women with premenstrual syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Pharmacological management of post-traumatic stress disorder: clinical summary of a five-year retrospective study, 1990-1995.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Alprazolam dependence prevented by substituting with the beta-carboline abecarnil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Role of GABA-A and mitochondrial diazepam binding inhibitor receptors in the anti-stress activity of neurosteroids in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Benzodiazepines on trial: a research strategy for their rehabilitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Clozapine treatment for a veteran with comorbid psychosis and PTSD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Hippocampal atrophy in recurrent major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

GABAA receptor subunit gene expression in human prefrontal cortex: comparison of schizophrenics and controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Does neurosteroid modulatory efficacy depend on GABAA receptor subunit composition?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Neurosteroids act on recombinant human GABAA receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Pharmacologic significance of the structural heterogeneity of the GABAA receptor-chloride ion channel complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

12 July 2018

From GABAA receptor diversity emerges a unified vision of GABAergic inhibition.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Serum allopregnanolone in women with postpartum "blues".

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Neurosteroids: endogenous allosteric modulators of GABA(A) receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Dopamine is involved in the antidepressant-like effect of allopregnanolone in the forced swimming test in female rats.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Antidepressant effect and changes of GABAA receptor gamma2 subunit mRNA after hippocampal administration of allopregnanolone in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Allopregnanolone microinjected into the lateral septum or dorsal hippocampus reduces immobility in the forced swim test: participation of the GABAA receptor.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Long-term social isolation enhances picrotoxin seizure susceptibility in mice: up-regulatory role of endogenous brain allopregnanolone in GABAergic systems

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Behaviorally selective effects of neuroactive steroids on plus-maze anxiety in mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Infusions of 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) to the ventral tegmental area, but not the substantia nigra, enhance exploratory, anti-anxiety, social and sexual behaviours and concomitantly increase 3alpha,5alpha-THP concentrations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Neuropeptide Y Y1 receptors in the central nucleus of amygdala mediate the anxiolytic-like effect of allopregnanolone in mice: Behavioral and immunocytochemical evidences.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

The anxiolytic-like effects of allopregnanolone vary as a function of intracerebral microinfusion site: the amygdala, medial prefrontal cortex, or hippocampus.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Changes in serotonin2A and GABA(A) receptors in schizophrenia: studies on the human dorsolateral prefrontal cortex.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Role of allopregnanolone on cerebellar granule cells neurogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Neuroscience: Editing out fear.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Low posttrauma GABA plasma levels as a predictive factor in the development of acute posttraumatic stress disorder

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

GABA(A) receptor beta 3 subunit gene and psychiatric morbidity in a post-traumatic stress disorder population.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Elevated circulatory level of GABA(A)--antagonistic neurosteroids in patients with combat-related post-traumatic stress disorder.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Elevated blood levels of dehydroepiandrosterone sulphate vary with symptom load in posttraumatic stress disorder: findings from a longitudinal study of refugees in Sweden

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Alcohol-induced exacerbation of ischemic brain injury: role of NAD(P)H oxidase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Fluoxetine prevents LPS-induced degeneration of nigral dopaminergic neurons by inhibiting microglia-mediated oxidative stress

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Long-term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal women modulates endocrine parameters and synthesis of neuroactive steroids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Dehydroepiandrosterone monotherapy in midlife-onset major and minor depression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Olanzapine treatment for post-traumatic stress disorder: an open-label study

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

A radical adventure: the quest for specific functions and inhibitors of vascular NAPDH oxidases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

Progesterone promotes the survival of newborn neurons in the dentate gyrus of adult male mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

25 September 2018

Paroxetine in the treatment of chronic posttraumatic stress disorder: results of a placebo-controlled, flexible-dosage trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

25 September 2018

Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABAA receptor activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02234.X

21 January 2018

3 alpha-hydroxysteroid dehydrogenase: three dimensional structure and gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245370

15 November 2018

Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The uniqueness of the DSM definition of post-traumatic stress disorder: implications for research

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dexamethasone regulation of the rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic mechanisms of hormone metabolism. I. Oxidation-reduction of the steroid nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAA receptor gamma subunits in the prefrontal cortex of patients with schizophrenia and bipolar disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The thalamic reticular nucleus: structure, function and concept

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ?isolation syndrome? in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychopharmacology of Aggression: an Overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desipramine enhances isolation-induced aggressive behavior in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticonvulsant action of allopregnanolone in immature rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21981145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2826.2011.02234.X

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

ResearchGate publication ID

0 references

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