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Mitochondrial p32 is a critical mediator of ARF-induced apoptosis
scientific article published in June 2008
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
title
Mitochondrial p32 is a critical mediator of ARF-induced apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
main subject
apoptotic process
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based on heuristic
inferred from title
author
Koji Itahana
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
author name string
Yanping Zhang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
publication date
1 June 2008
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stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
published in
Cancer Cell
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stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
volume
13
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
page(s)
542-553
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
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The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein
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PubMed Central
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Divorcing ARF and p53: an unsettled case
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11 July 2018
Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells
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PubMed Central
reference URL
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A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death
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PubMed Central
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Essential role of the B23/NPM core domain in regulating ARF binding and B23 stability
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Interactions between rubella virus capsid and host protein p32 are important for virus replication
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Apoptosis induced by adenovirus-mediated p14ARF expression in U2OS osteosarcoma cells is associated with increased Fas expression
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Cytochrome C-mediated apoptosis
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Receptor for the globular heads of C1q (gC1q-R, p33, hyaluronan-binding protein) is preferentially expressed by adenocarcinoma cells
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11 July 2018
Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32
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Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.
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p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice
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The Herpesvirus Saimiri open reading frame 73 gene product interacts with the cellular protein p32.
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Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
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11 July 2018
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An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo
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PubMed Central
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Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.
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PubMed Central
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11 July 2018
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
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11 July 2018
Differential detergent fractionation of eukaryotic cells. Analysis by two-dimensional gel electrophoresis
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11 July 2018
The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation
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PubMed Central
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11 July 2018
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
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11 July 2018
E1A signaling to p53 involves the p19(ARF) tumor suppressor
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PubMed Central
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11 July 2018
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
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PubMed Central
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11 July 2018
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11 July 2018
The multiligand-binding protein gC1qR, putative C1q receptor, is a mitochondrial protein.
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11 July 2018
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
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11 July 2018
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
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PubMed Central
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11 July 2018
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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11 July 2018
p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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11 July 2018
P32/TAP, a cellular protein that interacts with EBNA-1 of Epstein-Barr virus.
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PubMed Central
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11 July 2018
Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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11 July 2018
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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11 July 2018
Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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11 July 2018
Cellular protein modulates effects of human immunodeficiency virus type 1 Rev
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11 July 2018
A cell cycle regulator potentially involved in genesis of many tumor types
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11 July 2018
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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11 July 2018
Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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11 July 2018
Upregulation of hyaluronan binding protein 1 (HABP1/p32/gC1qR) is associated with Cisplatin induced apoptosis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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24 September 2018
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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24 September 2018
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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24 September 2018
The p16INK4a/CDKN2A tumor suppressor and its relatives.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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24 September 2018
Tumor surveillance via the ARF-p53 pathway.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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24 September 2018
Role of the INK4a locus in tumor suppression and cell mortality.
1 reference
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PubMed Central
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24 September 2018
Detailed computational study of p53 and p16: using evolutionary sequence analysis and disease-associated mutations to predict the functional consequences of allelic variants
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504427
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24 September 2018
Effects of Oligomycin on Respiration and Swelling of Isolated Liver Mitochondria
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18538737
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Human tumor suppressor ARF impedes S-phase progression independent of p53
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/18538737
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A nuclear envelope-associated kinase phosphorylates arginine-serine motifs and modulates interactions between the lamin B receptor and other nuclear proteins
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/18538737
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18538737
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18538737
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CCR.2008.04.002
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
PMC publication ID
4504427
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
PubMed publication ID
18538737
1 reference
stated in
Europe PubMed Central
PMC publication ID
4504427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18538737%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
ResearchGate publication ID
5318242
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