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DNA helicases involved in DNA repair and their roles in cancer
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
title
DNA helicases involved in DNA repair and their roles in cancer
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
author name string
Robert M Brosh
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
language of work or name
English
0 references
publication date
11 July 2013
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stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
published in
Nature Reviews Cancer
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stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
volume
13
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
issue
8
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
page(s)
542-558
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
exact match
https://scigraph.springernature.com/pub.10.1038/nrc3560
0 references
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Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaks
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Human RTEL1 deficiency causes Hoyeraal-Hreidarsson syndrome with short telomeres and genome instability
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FANCJ couples replication past natural fork barriers with maintenance of chromatin structure
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2 October 2017
Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response
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Constitutional mutations in RTEL1 cause severe dyskeratosis congenita
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Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
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FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress
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2 October 2017
DNA quality control by a lesion sensor pocket of the xeroderma pigmentosum group D helicase subunit of TFIIH.
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A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells
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Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in Dyskeratosis congenita
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FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress
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2 October 2017
Alternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progression
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DNA repair dysregulation from cancer driver to therapeutic target
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Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response
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Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes
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Molecular pathogenesis and clinical management of Fanconi anemia
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RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures
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PubMed Central
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Identification and biochemical characterization of a novel mutation in DDX11 causing Warsaw breakage syndrome
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DNA secondary structures: stability and function of G-quadruplex structures
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2 October 2017
Human RECQL5 participates in the removal of endogenous DNA damage
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PubMed Central
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SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions
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Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents
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Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function
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2 October 2017
Playing the end game: DNA double-strand break repair pathway choice
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The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
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An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks
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Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells
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PubMed Central
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2 October 2017
MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination
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PubMed Central
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2 October 2017
Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
RecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical coupling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Recruitment and retention dynamics of RECQL5 at DNA double strand break sites.
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2 October 2017
The conflict between DNA replication and transcription
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2 October 2017
RTEL1 contributes to DNA replication and repair and telomere maintenance.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function
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PubMed Central
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2 October 2017
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity
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2 October 2017
RECQ1 plays a distinct role in cellular response to oxidative DNA damage.
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2 October 2017
R loops: from transcription byproducts to threats to genome stability
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2 October 2017
Replication fork reversal after replication-transcription collision.
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2 October 2017
DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase.
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2 October 2017
Searching drug-like anti-cancer compound(s) based on G-quadruplex ligands
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2 October 2017
Polarity and bypass of DNA heterology during branch migration of Holliday junctions by human RAD54, BLM, and RECQ1 proteins
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2 October 2017
The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δ
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2 October 2017
A genomewide screen for suppressors of Alu-mediated rearrangements reveals a role for PIF1
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2 October 2017
DNA charge transport as a first step in coordinating the detection of lesions by repair proteins
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2 October 2017
Efficient coupling of ATP hydrolysis to translocation by RecQ helicase
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2 October 2017
DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster
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2 October 2017
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication
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2 October 2017
Shining a light on xeroderma pigmentosum
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2 October 2017
Defects in mitochondrial DNA replication and human disease
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2 October 2017
Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation
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2 October 2017
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.
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2 October 2017
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.
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2 October 2017
RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression
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2 October 2017
Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression
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2 October 2017
ATP-induced helicase slippage reveals highly coordinated subunits.
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2 October 2017
G-quadruplex-induced instability during leading-strand replication
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2 October 2017
Is telomerase a viable target in cancer?
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2 October 2017
The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation
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2 October 2017
The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks
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2 October 2017
Cancer biology and NuRD: a multifaceted chromatin remodelling complex
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2 October 2017
Interhomolog recombination and loss of heterozygosity in wild-type and Bloom syndrome helicase (BLM)-deficient mammalian cells
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2 October 2017
Mechanism of RAD51-dependent DNA interstrand cross-link repair.
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2 October 2017
DNA interstrand crosslink repair and cancer
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2 October 2017
Suppression of apoptosis by PIF1 helicase in human tumor cells
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2 October 2017
A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor.
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2 October 2017
RECQL1 and WRN proteins are potential therapeutic targets in head and neck squamous cell carcinoma
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2 October 2017
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.
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2 October 2017
Genome-wide comprehensive analysis of human helicases
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2 October 2017
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
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2 October 2017
Helicases that underpin replication of protein-bound DNA in Escherichia coli.
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2 October 2017
Human HEL308 localizes to damaged replication forks and unwinds lagging strand structures
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
The Werner syndrome protein: linking the replication checkpoint response to genome stability
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PubMed Central
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2 October 2017
Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1.
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PubMed Central
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2 October 2017
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Cancer susceptibility variants and the risk of adult glioma in a US case-control study.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Epigenetic instability due to defective replication of structured DNA.
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PubMed Central
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2 October 2017
The RecQ DNA helicases in DNA repair
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Human RecQL4 helicase plays critical roles in prostate carcinogenesis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Regulation of homologous recombination in eukaryotes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
G-quadruplex nucleic acids and human disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Components of the secondary pathway stimulate the primary pathway of eukaryotic Okazaki fragment processing
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Mechanistic and biological aspects of helicase action on damaged DNA.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Does a helicase activity help mismatch repair in eukaryotes?
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
RecQL1 DNA repair helicase: A potential tumor marker and therapeutic target against hepatocellular carcinoma.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Mismatch repair deficient colorectal cancer in the era of personalized treatment
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11/ChlR1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Roles of Werner syndrome protein in protection of genome integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
FANCC suppresses short telomere-initiated telomere sister chromatid exchange
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
DNA polymerase POLN participates in cross-link repair and homologous recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
RecQ helicases: multifunctional genome caretakers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Genome-wide association study identifies five susceptibility loci for glioma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Human Dna2 is a nuclear and mitochondrial DNA maintenance protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Hitting the bull's eye: novel directed cancer therapy through helicase-targeted synthetic lethality
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Structure of the human RECQ1 helicase reveals a putative strand-separation pin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Purification of proteins associated with specific genomic Loci
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
A role for monoubiquitinated FANCD2 at telomeres in ALT cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Making copies of chromatin: the challenge of nucleosomal organization and epigenetic information
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
HARP is an ATP-driven annealing helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
RTEL1 maintains genomic stability by suppressing homologous recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Remodeling of DNA replication structures by the branch point translocase FANCM
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
The mutation spectrum in RECQL4 diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Flap endonuclease 1 contributes to telomere stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Amplifying tumour-specific replication lesions by DNA repair inhibitors - a new era in targeted cancer therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
RecBCD enzyme switches lead motor subunits in response to chi recognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Human premature aging, DNA repair and RecQ helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Activation of BRCA1/BRCA2-associated helicase BACH1 is required for timely progression through S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Werner syndrome protein interacts functionally with translesion DNA polymerases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
Structure and mechanism of helicases and nucleic acid translocases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
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2 October 2017
The Werner and Bloom syndrome proteins catalyze regression of a model replication fork
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The Rothmund-Thomson gene product RECQL4 localizes to the nucleolus in response to oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: role of a highly conserved aromatic-rich sequence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Nucleotide excision repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Polymorphisms in the human XPD (ERCC2) gene, DNA repair capacity and cancer susceptibility: an appraisal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Essential role of limiting telomeres in the pathogenesis of Werner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The Werner syndrome protein has separable recombination and survival functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Stimulation of flap endonuclease-1 by the Bloom's syndrome protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Cancer predisposition caused by elevated mitotic recombination in Bloom mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Differential regulation of human RecQ family helicases in cell transformation and cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Structure and function of hexameric helicases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Ku complex interacts with and stimulates the Werner protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
A survey of telomerase activity in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Positional cloning of the Werner's syndrome gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The Bloom's syndrome gene product is homologous to RecQ helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
DNA mismatch correction in a defined system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Molecular cloning and biological characterization of the human excision repair gene ERCC-3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Correction of xeroderma pigmentosum complementation group D mutant cell phenotypes by chromosome and gene transfer: involvement of the human ERCC2 DNA repair gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
Enzymic Unwinding of DNA. 1. Purification and Characterization of a DNA-Dependent ATPase from Escherichia coli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
2 October 2017
The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
11 July 2018
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
11 July 2018
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
11 July 2018
Spring-loaded mechanism of DNA unwinding by hepatitis C virus NS3 helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
11 July 2018
Characterization of a complex chromosomal rearrangement maps the locus for in vitro complementation of xeroderma pigmentosum group D to human chromosome band 19q13
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
11 July 2018
The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
The Bloom's syndrome helicase can promote the regression of a model replication fork.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
Repetitive shuttling of a motor protein on DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538698
retrieved
24 September 2018
Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRC3560
retrieved
31 March 2020
Allosteric effects of nucleotide cofactors on Escherichia coli Rep helicase-DNA binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRC3560
retrieved
31 March 2020
BACH1 is a DNA repair protein supporting BRCA1 damage response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRC3560
retrieved
31 March 2020
Identifiers
DOI
10.1038/NRC3560
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
PMCID
4538698
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
PubMed ID
23842644
1 reference
stated in
Europe PubMed Central
PMCID
4538698
retrieved
11 August 2017
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